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Geraniol is a potent inducer of apoptosis-like cell death in the cultured shoot primordia of Matricaria chamomilla.

Abstract：

:We screened various isoprenoids to search for inducers of apoptosis-like cell death ("apoptosis") in the shoot primordia of Matricaria chamomilla and found that geraniol has the most potent apoptosis-inducing activity among terpenoids, as judged from DNA fragmentation in the cells. The apoptosis-inducing activity of geraniol is concentration and time dependent. Morphologically, the nuclei of the cells treated with 5 mM geraniol were condensed and fragmented.

journal_name

Biochem Biophys Res Commun

journal_title

Biochemical and biophysical research communications

authors

Izumi S,Takashima O,Hirata T

doi

10.1006/bbrc.1999.0813

subject

Has Abstract

pub_date

1999-06-16 00:00:00

pages

519-22

issue

3

eissn

0006-291X

issn

1090-2104

pii

S0006-291X(99)90813-6

journal_volume

259

pub_type

杂志文章

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