Abstract:
:A histopathological study of coronary arteries in patients with acute coronary syndromes was carried out. The results of this study are as follows: 1. A high incidence of thrombus formation, corresponding to the site of the infarction, was observed in cases with acute myocardial infarction. 2. Coronary thrombi containing plaque components such as foam cells, cholesterol clefts, and fractured intimal collagen fibers were detected. 3. Patients who succumbed suddenly after coronary attack had ruptured atheromatous plaque only, but not a thrombus. As these patients showed severe stenosis with recanalization in 2 of the 3 main coronary arteries, the rupture of the plaque caused significant occlusion of the remaining coronary artery. 4. Increase of intra-plaque pressure resulting from a honeycomb-like accumulation of foam cells, cholesterin clefts, and blood infiltration from lumen to plaque through the injured endothelial cells is the cause of rupture of the atheromatous plaque. This rupture into the lumen might precede, and be responsible for formation of the thrombus and onset of acute coronary syndromes.
journal_name
J Cardioljournal_title
Journal of cardiologyauthors
Horie Tsubject
Has Abstractpub_date
1999-03-01 00:00:00pages
3-8eissn
0914-5087issn
1876-4738journal_volume
33 Suppl 1pub_type
杂志文章,评审abstract::A 71-year-old woman was admitted to our department because of acute myocarditis. She was ameliorated with conventional heart failure treatment, however she developed left ventricular dilatation and cardiac troponin T (cTnT) was elevated again to >1.0 ng/ml 6 month after the first admission. She was re-admitted because...
journal_title:Journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.jjcc.2008.05.002
更新日期:2008-10-01 00:00:00
abstract::In the early stages of arterial hypertension, increased contractility, demonstrated by calibrated and differentiated apexcardiography is present. Already in this early phase of the disease the criteria of diastolic function, as during isovolumetric period (calibrated and differentiated apexcardiography, M-mode echocar...
journal_title:Journal of cardiology
pub_type: 杂志文章
doi:
更新日期:2001-01-01 00:00:00
abstract:BACKGROUND:Missense mutations in KCNH2, a gene encoding the Kv11.1 channel, cause long QT syndrome (LQTS) type 2 primarily by disrupting the intracellular transport of Kv11.1 to the plasma membrane. The present study aimed to clarify the functional changes by two novel KCNH2 missense mutations. METHODS:We performed ge...
journal_title:Journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.jjcc.2017.10.004
更新日期:2018-04-01 00:00:00
abstract::Chronic aortic regurgitation (AR) is a disease incorporating volume overload of the left ventricle (LV) which is characterized by hyperactive left ventricular dilatation (LVD). However, we have encountered several patients who had concentric LV hypertrophy (LVH) instead of LVD. We therefore studied 50 consecutive pati...
journal_title:Journal of cardiology
pub_type: 杂志文章
doi:
更新日期:1989-12-01 00:00:00
abstract::During ergonovine-induced vasospastic angina, U wave inversion without significant ST segment deviation on the precordial electrocardiograms was documented in four patients. Coronary angiography revealed incomplete spastic obstruction of the left anterior descending artery without delayed filling and runoff in three p...
journal_title:Journal of cardiology
pub_type: 杂志文章
doi:
更新日期:1989-09-01 00:00:00
abstract:BACKGROUND:Although the Klotho gene is recognized as an aging-suppressor gene, the clinical significance of its soluble product, soluble Klotho, in coronary artery disease (CAD) has not been completely determined. The relationship between soluble Klotho and coronary artery calcification (CAC) was investigated in patien...
journal_title:Journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.jjcc.2020.11.014
更新日期:2020-12-07 00:00:00
abstract:BACKGROUND:Left ventricular diastolic dysfunction (LVDD) plays an important role in heart failure with normal left ventricular ejection fraction (LVEF). Obesity is one of the major comorbid conditions of LVDD. Pericardial fat (PF) is an ectopic fat depot with possible paracrine or mechanical effects on the coronary cir...
journal_title:Journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.jjcc.2012.01.006
更新日期:2012-05-01 00:00:00
abstract:OBJECTIVES:Only a few examinations are available to critically ill patients. We assessed the efficacy of transesophageal echocardiography (TEE) in the management of patients with cardiac arrest or shock. METHODS:Among a total of 2,021 patients who underwent TEE over the past 13 years at our institution, we reviewed 18...
journal_title:Journal of cardiology
pub_type: 杂志文章
doi:
更新日期:2004-11-01 00:00:00
abstract::Major pathophysiology of heart failure is an autonomic nervous system dysfunction as a result of excess sympathoexcitation and/or withdrawal of vagal nerve activity. Although we already have various pharmacological and non-pharmacological therapies for heart failure, survival of heart failure patients remains around 5...
journal_title:Journal of cardiology
pub_type: 杂志文章,评审
doi:10.1016/j.jjcc.2016.05.010
更新日期:2016-11-01 00:00:00
abstract:BACKGROUND:Although tolvaptan is a recently approved drug for heart failure and causes aquaresis without affecting renal function, its clinical efficacy for patients with acute decompensated heart failure (ADHF) is yet to be elucidated. METHODS AND RESULTS:We conducted a prospective observational study in patients wit...
journal_title:Journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.jjcc.2012.08.020
更新日期:2013-02-01 00:00:00
abstract::Percutaneous transvenous mitral valvuloplasty (PTMV) using the Inoue balloon was performed in 18 patients with symptomatic mitral stenosis. They were seven men and 11 women, ranging in age from 38 to 77 years (mean 59 +/- 10 years). Among them, 13 were categorized as NYHA class II; four as class III; and one as class ...
journal_title:Journal of cardiology
pub_type: 杂志文章
doi:
更新日期:1989-03-01 00:00:00
abstract::The usefulness of electrophysiologic study and Holter monitoring for predicting the long-term efficacy of amiodarone was investigated in 31 patients with sustained ventricular tachycardia (VT) and organic heart disease. Patients underwent both electrophysiologic study and Holter monitoring before and during oral admin...
journal_title:Journal of cardiology
pub_type: 临床试验,杂志文章
doi:
更新日期:1996-11-01 00:00:00
abstract::The floppy mitral valve prolapses into the left atrium in such a dynamic manner that the prolapsing floppy mitral valve becomes a space-occupying lesion within the left atrium. A significant result of the floppy mitral valve prolapsing into the left atrium during left ventricular systole is the development of a "third...
journal_title:Journal of cardiology
pub_type: 杂志文章,评审
doi:
更新日期:2001-01-01 00:00:00
abstract:BACKGROUND:There is little information about the relationship between J waves and the occurrence of ventricular fibrillation (VF) in patients with vasospastic angina (VSA). The present study aimed to assess the incidence of J waves and the occurrence of VF in patients with VSA. METHODS:The subjects consisted of 62 pat...
journal_title:Journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.jjcc.2016.12.003
更新日期:2017-09-01 00:00:00
abstract:BACKGROUND:Chronic renal disease (CKD) is a determinant of coronary artery calcification (CAC), which is a predictor of cardiovascular events. However, in a population without CKD, the association between CAC and renal function is unclear. CAC is affected by sex. This study aimed to determine whether serum cystatin C, ...
journal_title:Journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.jjcc.2017.05.001
更新日期:2017-12-01 00:00:00
abstract:BACKGROUND:Increased levels of uric acid (UA) have been associated with cardiovascular disease. This association is generally stronger in women than men. However, gender differences in the prognostic value of UA in patients with acute coronary syndrome (ACS) are unknown. We investigated gender differences in the relati...
journal_title:Journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.jjcc.2015.05.009
更新日期:2016-02-01 00:00:00
abstract::A 57-year-old man was admitted under a diagnosis of myocardial infarction. Cardiac catheterization revealed total occlusions of the right coronary artery and the left anterior descending artery, and ventriculography showed aneurysmal change in the anterior and septal segments. Circulatory support was introduced with i...
journal_title:Journal of cardiology
pub_type: 杂志文章
doi:
更新日期:2004-05-01 00:00:00
abstract:OBJECTIVES:The aim of this study was to assess the effect of eicosapentaenoic acid (EPA) on peri-procedural (type IVa) myocardial infarction (MI) following elective percutaneous coronary intervention (PCI). METHODS AND RESULTS:We analyzed data from 165 of 178 consecutive patients with stable angina pectoris who underw...
journal_title:Journal of cardiology
pub_type: 临床试验,杂志文章
doi:10.1016/j.jjcc.2014.09.004
更新日期:2015-08-01 00:00:00
abstract:OBJECTIVES:Recent studies have demonstrated that not only plasma low-density lipoprotein (LDL) levels, but also the number of small dense LDL particles are involved in the development of arteriosclerosis. Anion exchange resins can reduce plasma LDL levels and affect LDL particle size via increasing triglycerides. In th...
journal_title:Journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.jjcc.2009.08.006
更新日期:2010-01-01 00:00:00
abstract:BACKGROUND:On March 11, 2011, the Tohoku district was struck by the most powerful known earthquake to hit Japan. Although stress-induced heart diseases rise after strong psychosocial stress, little is known about the characteristics of heart failure (HF) caused by psychosocial stress related to earthquakes. METHODS:We...
journal_title:Journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.jjcc.2013.02.015
更新日期:2013-07-01 00:00:00
abstract:BACKGROUND:Syndecan-4 is a transmembrane heparan sulfate-carrying glycoprotein that mediates signal transduction pathways activated by growth factors and cell surface receptors, thereby modulating tissue regeneration, angiogenesis, and focal adhesion. The aim of the present study was to determine the clinical use of se...
journal_title:Journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.jjcc.2011.01.012
更新日期:2011-05-01 00:00:00
abstract::To assess the relative importance of the anatomical characteristics of the coronary artery distribution and the sites of the arterial stenoses in relation to infarct size, 21 patients with old myocardial infarction and angiographically-proven 90% or greater stenoses (AHA classification) of one of the major coronary ar...
journal_title:Journal of cardiology
pub_type: 杂志文章
doi:
更新日期:1988-03-01 00:00:00
abstract:BACKGROUND:Based on the importance of left ventricular (LV) diastolic function in stratification of the cardiac prognosis in patients with systolic heart failure (SHF), we attempted to identify the prognostic impact of Doppler echocardiographic examinations and plasma B-type natriuretic peptide (BNP) concentration. ME...
journal_title:Journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.jjcc.2008.07.008
更新日期:2008-12-01 00:00:00
abstract:BACKGROUND:Previous studies have reported diffuse destabilization of atherosclerotic plaques in acute myocardial infarction (AMI). We used intravascular ultrasound (IVUS) to assess coronary culprit lesions in ST segment elevation MI (STEMI) vs. in non-ST segment elevation MI (NSTEMI). METHODS:Patient population compri...
journal_title:Journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.jjcc.2010.01.010
更新日期:2010-07-01 00:00:00
abstract::A 47-year-old man with heterozygous familial hypercholesterolemia was followed up by coronary angiography for 9 years. During these 9 years, he experienced inferior myocardial infarction twice, at segment 1 of the right coronary artery. A coronary atherosclerotic lesion (50% stenosis) was also present at segment 6 of ...
journal_title:Journal of cardiology
pub_type: 杂志文章
doi:
更新日期:1997-09-01 00:00:00
abstract:BACKGROUND:Cardiovascular diseases are the leading cause of death in elderly people. Over the past decades medical advancements in the management of patients with acute myocardial infarction (AMI) led to improved survival and increased life expectancy. As short-term survival from AMI improves, more attention is being s...
journal_title:Journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.jjcc.2014.06.001
更新日期:2015-03-01 00:00:00
abstract::A 67-year-old man with exertional angina presented with a large pseudoaneurysm of the right coronary artery at eight months after balloon angioplasty. Intravascular ultrasound revealed a large saccular pseudoaneurysm of 10.9 x 5.7 mm diameter at the proximal segment of the right coronary artery. Complete closure of th...
journal_title:Journal of cardiology
pub_type: 杂志文章
doi:
更新日期:2003-12-01 00:00:00
abstract:BACKGROUND:This study was performed to investigate whether combined use of high-sensitivity C-reactive protein (hs-CRP) levels and coronary computed tomography angiography (CCTA) results have additional prognostic value for predicting cardiovascular events in patients with suspected coronary artery disease (CAD). METH...
journal_title:Journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.jjcc.2015.09.010
更新日期:2016-09-01 00:00:00
abstract::The treadmill exercise test (TET) is evaluated by exercise-induced ST-segment depression (delta ST). However, the depression sometimes only appears during the post-exercise period. Depression appearing only during the post-exercise period may be as useful as depression during exercise to predict coronary artery diseas...
journal_title:Journal of cardiology
pub_type: 临床试验,杂志文章
doi:
更新日期:1996-05-01 00:00:00
abstract::Four patients with acute myocardial infarction (MI) complicating double rupture; interventricular septum and ventricular free wall ruptures, were studied. All patients had histories of hypertension, and pre-infarction angina pectoris of short duration less than 8 days without previous MI. The sites of infarction were ...
journal_title:Journal of cardiology
pub_type: 杂志文章
doi:
更新日期:1991-01-01 00:00:00