Abstract:
:We have used a subtractive method to clone novel messages enriched in the heart. Here we show that one such message, bves (blood vessel/epicardial substance) is a novel protein that is highly conserved between chicken and mouse. The bves message is detected at high levels in early chick hearts. Using anti-Bves antibodies, we show expression in cells of the proepicardial organ, migrating epicardium, epicardial-derived mesenchyme, and smooth muscle of the developing intracardiac arterial system, including the coronary arteries. Our data suggest that Bves is an early marker of developing vascular smooth muscle cells. In addition, the expression pattern of Bves protein reveals the patterning of intracardiac vascular smooth muscle and possible insights into the cellular regulation of smooth muscle differentiation during vasculogenesis.
journal_name
Dev Bioljournal_title
Developmental biologyauthors
Reese DE,Zavaljevski M,Streiff NL,Bader Ddoi
10.1006/dbio.1999.9246subject
Has Abstractpub_date
1999-05-01 00:00:00pages
159-71issue
1eissn
0012-1606issn
1095-564Xpii
S0012-1606(99)99246-1journal_volume
209pub_type
杂志文章abstract::The organizer is an essential signaling center required for axial formation during vertebrate embryonic development. In the basal chordate amphioxus, the dorsal blastopore lip of the gastrula has been proposed to be homologous to the vertebrate organizer. Lefty is one of the first genes to be expressed in the organize...
journal_title:Developmental biology
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journal_title:Developmental biology
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journal_title:Developmental biology
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journal_title:Developmental biology
pub_type: 杂志文章
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journal_title:Developmental biology
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journal_title:Developmental biology
pub_type: 杂志文章
doi:10.1016/j.ydbio.2005.07.033
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journal_title:Developmental biology
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journal_title:Developmental biology
pub_type: 杂志文章
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abstract::Vertebrate morphology has been evolutionarily modified by natural and/or artificial selection. The morphological variation of goldfish is a representative example. In particular, the twin-tail strain of ornamental goldfish shows highly diverged anal and caudal fin morphology: bifurcated anal and caudal fins. Recent mo...
journal_title:Developmental biology
pub_type: 杂志文章,评审
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更新日期:2017-07-15 00:00:00
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journal_title:Developmental biology
pub_type: 杂志文章
doi:10.1016/j.ydbio.2007.06.007
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pub_type: 杂志文章,评审
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journal_title:Developmental biology
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journal_title:Developmental biology
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journal_title:Developmental biology
pub_type: 杂志文章
doi:10.1016/0012-1606(88)90247-3
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journal_title:Developmental biology
pub_type: 杂志文章
doi:10.1016/j.ydbio.2007.01.015
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journal_title:Developmental biology
pub_type: 杂志文章
doi:10.1016/j.ydbio.2007.07.023
更新日期:2007-10-15 00:00:00
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journal_title:Developmental biology
pub_type: 杂志文章
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journal_title:Developmental biology
pub_type: 杂志文章
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journal_title:Developmental biology
pub_type: 杂志文章
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journal_title:Developmental biology
pub_type: 杂志文章
doi:10.1016/j.ydbio.2005.12.015
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