Abstract：
OBJECTIVE:To compare the effects of a 6-month treatment with intravenous pamidronate (30-mg infusion once per month) to conventional rehabilitation without pamidronate on bone density of the spine and leg bones and on the excretion rate of N-telopeptide, a urinary marker of bone catabolism, in acutely spinal cord injured patients. DESIGN:A nonrandomized control trial in which 24 spinal cord injured subjects entered the study within 6 weeks of their injury. Fourteen subjects received pamidronate; 10 did not. OUTCOME MEASURES:Bone density measurements by dual x-ray absorptiometry were performed before the initial treatment (within 6 weeks of the injury) and at 3, 6, and 12 months postinjury and was the primary efficacy parameter. Urine for N-telopeptide levels was the secondary efficacy parameter. RESULTS:After acute spinal cord injury, patients treated with intravenous pamidronate had significantly less bone density loss compared with those who did not receive pamidronate (parametric ANOVA, p<.02). Also, ambulatory subjects had significantly less bone density loss over the study period (p<.05) than nonambulatory subjects. In general, a high excretion level of the urinary bone-breakdown product N-telopeptide was found before intravenous pamidronate treatment, followed by a dramatic reduction in excretion after pamidronate treatment. Ambulatory subjects excreted significantly less N-telopeptide than motor-complete subjects at all time points. CONCLUSION:Intravenous pamidronate treatment and ambulatory ability in the first 6 months after an acute spinal cord injury prevents bone density loss.
journal_name
Arch Phys Med Rehabiljournal_title
Archives of physical medicine and rehabilitationauthors
Nance PW,Schryvers O,Leslie W,Ludwig S,Krahn J,Uebelhart Ddoi
10.1016/s0003-9993(99)90133-8subject
Has Abstractpub_date
1999-03-01 00:00:00pages
243-51issue
3eissn
0003-9993issn
1532-821Xpii
S0003-9993(99)90133-8journal_volume
80pub_type
临床试验,杂志文章abstract：OBJECTIVE:To determine the reliability, validity, and responsiveness of the modified Kapandji index (MKI). DESIGN:Prospective study. A cohort of patients planned for surgery of the wrist and/or fingers was evaluated within 48 hours before surgery and at least 6 months after surgery. SETTING:Patients were in hospitali...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章
doi：10.1016/s0003-9993(03)00128-x
更新日期：2003-07-01 00:00:00
abstract：:To evaluate the efficacy and function of EMG feedback (FB) in muscle reeducation, voluntary muscle contractions with and without EMG FB were compared under controlled experimental conditions in normal human subjects (n=10). Each subject was instructed to produce 12 sustained, 30-second contractions of the left abducto...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章
doi：
更新日期：1982-06-01 00:00:00
abstract：OBJECTIVE:To examine functional outcome and descriptive data of individuals with neoplastic spinal cord compression admitted to a rehabilitation unit. DESIGN:A 5-year review of consecutive patients admitted to a spinal cord injury rehabilitation unit with a diagnosis of neoplastic spinal cord compression. SETTING:A t...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章
doi：10.1016/s0003-9993(96)90276-2
更新日期：1996-09-01 00:00:00
abstract：OBJECTIVES:To identify randomized controlled trials comparing the use of hydrophilic and nonhydrophilic catheters for intermittent catheterization (IC) in patients with spinal cord injury (SCI), and to perform a meta-analysis evaluating the occurrence of hematuria and urinary tract infection (UTI). DATA SOURCES:We sea...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章,meta分析,评审
doi：10.1016/j.apmr.2012.11.010
更新日期：2013-04-01 00:00:00
abstract：OBJECTIVE:To evaluate the effect of depression on functional recovery in geriatric patients who have completed an inpatient rehabilitation program. DESIGN:Prospective cohort study. SETTING:Inpatient rehabilitation unit of a university-affiliated geriatric hospital. PARTICIPANTS:Convenience sample of patients (N=65; ...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章
doi：10.1016/j.apmr.2016.07.014
更新日期：2017-03-01 00:00:00
abstract：OBJECTIVES:To investigate the effects of dual-task balance training on static and dynamic balance, functional mobility, cognitive level, and sleep quality in individuals with transfemoral amputation. DESIGN:Randomized controlled clinical trial. PARTICIPANTS:Transfemoral amputees (N=20). INTERVENTIONS:Participants we...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.apmr.2020.06.009
更新日期：2020-10-01 00:00:00
abstract：OBJECTIVE:To translate and assess the reliability and the construct validity of 3 functional disability scales for neck pain. DESIGN:Reliability and validity study. SETTING:Tertiary care teaching hospital and outpatient clinic. PARTICIPANTS:One hundred one patients (mean age, 49 y). INTERVENTION:French translations...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章
doi：10.1053/apmr.2002.30623
更新日期：2002-03-01 00:00:00
abstract：:Botulinum toxin type A is effective in treating neurologic entities with increased muscle tone. Few reports show the benefits of this treatment for orthopedic conditions. We present the case of a 54-year-old man who manifested bilateral pectoralis major stiffness and bilateral shoulder pain; he had a score of 6 on a v...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章
doi：10.1016/s0003-9993(03)00044-3
更新日期：2003-07-01 00:00:00
abstract：:A standardized method of obtaining distal motor latencies of the medial and lateral plantar nerves over fixed distances with temperature correction in 37 normal subjects is presented. The posterior tibial nerve was supramaximally stimulated 6, 8, 10, 12 and 14cm proximal to the active electrode over the motor point of...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章
doi：
更新日期：1980-06-01 00:00:00
abstract：:In a 13-month period, 41 selected patients with cerebrovascular accidents were studied utilizing computerized tomography of the brain and the Barthel index in an attempt to correlate findings with final rehabilitation outcome. Parameters that were studied included age, sex, lesion size and location, and functional sta...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章
doi：
更新日期：1984-09-01 00:00:00
abstract：OBJECTIVE:To examine the effect of different levels of fractional inspired oxygen (FiO(2)) (15%, 21%, 50%) on peak oxygen consumption (VO(2)peak) during arm exercise in persons with spinal cord injury and in able-bodied controls. DESIGN:Case-control study. SETTING:University medical center in the Netherlands. PARTIC...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章
doi：10.1016/j.apmr.2003.02.001
更新日期：2004-02-01 00:00:00
abstract：OBJECTIVE:To investigate the effects of combination cathodal transcranial direct current stimulation (tDCS) and virtual reality (VR) therapy for upper extremity (UE) training in patients with subacute stroke. DESIGN:Pilot randomized controlled trial. Patients were randomly assigned to 1 of 3 groups: group A received c...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.apmr.2013.10.027
更新日期：2014-03-01 00:00:00
abstract：OBJECTIVE:To assess the efficacy of extracorporeal shockwave therapy (ESWT) and provide clinicians with an evidence base for their clinical decision making. DATA SOURCES:PubMed, MEDLINE, Embase, Cochrane Central Register of Controlled Trials, and Evidence-Based Medicine Reviews. STUDY SELECTION:All randomized or quas...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章,meta分析,评审
doi：10.1016/j.apmr.2014.01.033
更新日期：2014-08-01 00:00:00
abstract：:The term "EMG disease" is used by some to describe the unexpected finding of diffusely increased insertional activity on needle electromyography in an otherwise asymptomatic person. The cause is unknown, but it has been hypothesized that these patients actually have a subclinical myotonic disorder. We describe 2 patie...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章
doi：10.1016/j.apmr.2007.06.013
更新日期：2007-09-01 00:00:00
abstract：OBJECTIVE:To investigate the effects of long-term Tai Chi practice on balance control when healthy elderly Tai Chi practitioners stood under reduced or conflicting somatosensory, visual, and vestibular conditions, as compared with healthy elderly non-Tai Chi practitioners and young subjects. DESIGN:Cross-sectional stu...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章
doi：10.1016/j.apmr.2003.02.002
更新日期：2004-01-01 00:00:00
abstract：:This study was undertaken to determine whether adaptations to short-term exercise training after myocardial infarction, could affect the response of heart rate, blood pressure and double product at submaximal workload, and the behavior of electrocardiographic ST segment depression. We studied 60 patients (group A) who...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/s0003-9993(95)80613-x
更新日期：1995-03-01 00:00:00
abstract：OBJECTIVE:To determine whether the administration of clenbuterol, a beta2-adrenergic agonist, prevents loss of muscle mass during a period of imposed inactivity. DESIGN:Randomized trial. SETTING:Basic laboratory research. ANIMALS:Thirty Fischer 344 Brown Norway F1 Hybrid rats, 12 and 30 months of age. INTERVENTIONS...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1053/apmr.2001.23756
更新日期：2001-07-01 00:00:00
abstract：OBJECTIVE:To identify determinants for the use of a walking device in persons with Parkinson's disease (PD). DESIGN:Cross-sectional study of participants with PD. SETTING:Laboratory. PARTICIPANTS:Persons with PD (N=85; 60 men) were studied. Their mean age was 69.4±8.9 years. The average time since diagnosis was 7.9±...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章
doi：10.1016/j.apmr.2014.06.002
更新日期：2014-10-01 00:00:00
abstract：:In clinical trials, the choice of the primary outcome affects the study design, the sample size calculations, the data analysis, and the interpretation of the study results. Most importantly, it may determine the future of the intervention being studied. In several clinical and rehabilitation settings, a single primar...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章
doi：10.1016/j.apmr.2009.08.133
更新日期：2009-11-01 00:00:00
abstract：OBJECTIVE:The potential effect of ethnicity on the serum lipid profile and lipoprotein(a) [Lp(a)] was studied in a population with chronic spinal cord injury (SCI). STUDY DESIGN:The distribution and correlates of high density lipoprotein (HDL) cholesterol and Lp(a) were studied in a population of 600 subjects with chr...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章
doi：10.1016/s0003-9993(98)90296-9
更新日期：1998-02-01 00:00:00
abstract：OBJECTIVE:To compare results of the observational Wisconsin Gait Scale (WGS) and global gait indexes such as Gait Deviation Index (GDI) and Gait Variability Index (GVI), constituting an objective method of assessing gait, and taking into account parameters identified during 3-dimensional gait analysis (3DGA). DESIGN:A...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章
doi：10.1016/j.apmr.2018.12.031
更新日期：2019-09-01 00:00:00
abstract：OBJECTIVE:To evaluate the relationship between caregiver nature and availability, and rehabilitation outcomes in subacute stroke. DESIGN:Retrospective cohort study. SETTING:Four community rehabilitation hospitals. PARTICIPANTS:Patients with subacute, first-time stroke (N=4042; 48.5% men; mean age ± SD, 70.12±10.4y; ...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章
doi：10.1016/j.apmr.2017.02.021
更新日期：2017-10-01 00:00:00
abstract：OBJECTIVE:To compare isometric torque and cycling power, smoothness and symmetry using repetitive functional magnetic stimulation (FMS) and functional electrical stimulation (FES) in patients with paretic legs with preserved sensibility and in patients without sensibility. DESIGN:Repeated-measures design. SETTING:Lab...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 临床试验,杂志文章
doi：10.1016/j.apmr.2008.09.572
更新日期：2009-04-01 00:00:00
abstract：OBJECTIVE:To assess perceptual performances of patients with intracerebral hemorrhage (ICH) compared with those of ischemic patients early after stroke and to analyze the psychometric properties of three perceptual tests used in the study. DESIGN:Cross-sectional study. SETTING:A rehabilitation unit at a teaching hosp...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章
doi：10.1016/s0003-9993(00)90097-2
更新日期：2000-06-01 00:00:00
abstract：:Results of a mail survey of physiatrists and residents in physical medicine and rehabilitation indicate that physiatrists need administrative/managerial skills in their practices. For physiatrists to initiate new programs, they need skills in program planning and development, resource management, and similar areas. Ex...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章
doi：
更新日期：1991-05-01 00:00:00
abstract：OBJECTIVE:To develop a valid and reliable spinal cord injury (SCI) specific physical functioning (PF) scale for the Veterans Health Administration (VHA) version of the 36-Item Short-Form Health Survey. DESIGN:A mixed qualitative and quantitative research design was used. In phase 1, a pool of SCI-specific PF items was...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章
doi：10.1016/j.apmr.2006.05.010
更新日期：2006-08-01 00:00:00
abstract：OBJECTIVE:To identify the factors that influence an individual's quality of life (QOL) after spinal cord injury (SCI) based on the International Classification of Functioning, Disability and Health (ICF) framework. DESIGN:Cross-sectional exploratory study. SETTING:Taiwan community. PARTICIPANTS:Community-dwelling ad...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章
doi：10.1016/j.apmr.2012.06.008
更新日期：2012-12-01 00:00:00
abstract：:This study was designed to determine the following about a geriatric rehabilitation population: (1) the relationship between patients' self-reports of depression and anxiety and staff observations of compromised participation in treatment secondary to emotional dysfunction; (2) the relationship of observations among d...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章
doi：
更新日期：1992-06-01 00:00:00
abstract：:A case is presented of a woman who had an occlusive stroke at age 29. She was seen in a rehabilitation medicine clinic for central nervous system-mediated pain that had developed soon after a cerebrovascular event. After an extensive workup to find the cause of her cerebrovascular occlusion, it was discovered that she...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章
doi：10.1016/s0003-9993(98)90018-1
更新日期：1998-03-01 00:00:00
abstract：:A study of 9,135 persons injured between 1973 and 1984 and treated at any of 13 regional spinal cord injury care systems was conducted to compare their age-, sex-, race-, and cause-specific mortality rates with those of the general population. All subjects survived at least 24 hours. Follow-up was terminated in Decemb...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章
doi：
更新日期：1993-03-01 00:00:00
