Silver staining method for demonstrating Lewy bodies in Parkinson's disease and argyrophilic oligodendrocytes in multiple system atrophy.

Abstract:

:A reliable and economical silver staining method is recommended for demonstration of Lewy bodies (LB) and Lewy neurites (LN) in Parkinson's disease (PD) and of argyrophilic oligodendrocytes in multiple system atrophy (MSA). The technique can be applied to routinely formalin-fixed autopsy material and does not require particular skills. It permits processing of frozen sections and sections from polyethylene glycol or paraffin embedded material. It takes advantage of the physical development of nucleation sites and thereby permits tight control of the entire staining procedure.

journal_name

J Neurosci Methods

authors

Braak E,Braak H

doi

10.1016/s0165-0270(98)00173-3

subject

Has Abstract

pub_date

1999-02-01 00:00:00

pages

111-5

issue

1

eissn

0165-0270

issn

1872-678X

pii

S0165027098001733

journal_volume

87

pub_type

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