Abstract：
:Ten hamsters received repeated injections of 3H-thymidine for 4 days and were allowed to survive for 7, 28, 42 and 100 days. Changes in spatial distribution of the labelled cells and in labelling indices of each cell line in the gastric glands were studied at various days after 3H-thymidine, the labelled parietal cells and the mucous neck cells were concentrated at the neck area. Starting from the neck area, they migrated an average of 3 micra downwards per day. By 42 days, they reached the middle level of the glands, where the labelled mucous neck cells decreased but the labelled chief cells increased in number. The differentiation of the chief cell then appears to take place at the middle level of the glands through transformation of the migratory mucous neck cells. After 4 days of the labelling, about 1.8% of the chief cells located in the lower part of the glands was found to undergo in situ replication. This indicates that the renewal of this cell type is partly assured by its own mitotic activity. The foveolar cell--the future surface epithelium--seems to migrate upwards along the long axis of the glandular tubule in the pipe line system, which means "first produced, first migrates". After migrating out from the neck area, the parietal cell and the mucous neck cell (the future chief cell) take an average of 200 days to reach the lower end of the glands. In the process of migration, however, the cells produced contemporaneously at the neck area became scatteringly spread from the neck towards the bottom of the gland. The time required for the newly-formed cells to reach the lower end of the gland varied between 100 and 300 days. In the gastric glands the cells first produced at the neck area do not first reach the lower end of the glands. This mode of random migration is referred to as the "stochastic flow system". As one of the probable factors which disturb the pipe line flow of downward cell migration, cellular movements perpendicular to the long axis of the glandular tubule were suggested to occur at random at any level of the gastric glands.
journal_name
Cell Tissue Resjournal_title
Cell and tissue researchauthors
Hattori T,Fujita Sdoi
10.1007/BF00226025subject
Has Abstractpub_date
1976-09-14 00:00:00pages
171-84issue
2eissn
0302-766Xissn
1432-0878journal_volume
172pub_type
杂志文章abstract：:Fibrosis is the result of a wound-healing response that fails to restore normal tissue structure function. One of the critical hallmarks of fibrosis is disrupted collagen remodeling. In tissue homeostasis, the production, deposition and organization of collagen is balanced by the degradation and remodeling of collagen...
journal_title：Cell and tissue research
pub_type： 杂志文章,评审
doi：10.1007/s00441-016-2440-8
更新日期：2016-09-01 00:00:00
abstract：:A multilamellate body (MLB), bearing close resemblance to an array of annulate lamellae, has been observed in several adenohypophysial cell types of the teleost, Hemihaplochromis philander. In longitudinal section, each MLB comprises a ladder-like row of 12-50 sausage-shaped profiles, termed lamellae. A few lamellae i...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00221372
更新日期：1976-10-06 00:00:00
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journal_title：Cell and tissue research
pub_type： 杂志文章
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更新日期：1979-11-01 00:00:00
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journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00209980
更新日期：1981-01-01 00:00:00
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journal_title：Cell and tissue research
pub_type： 杂志文章,评审
doi：10.1007/s00441-013-1655-1
更新日期：2013-12-01 00:00:00
abstract：:The kidney is an organ involved in cross talk with many human organs. The link between the immune system and the kidney has been studied in some detail, although data precisely elucidating their interaction are sparse, in particular with regard to the function of the kidney filter apparatus. Current research suggests ...
journal_title：Cell and tissue research
pub_type： 杂志文章,评审
doi：10.1007/s00441-017-2635-7
更新日期：2017-07-01 00:00:00
abstract：:Caprine preantral follicles within ovarian fragments were cryopreserved in the absence or presence of 0.5 M sucrose with or without 1 M dimethyl sulfoxide and/or 1 M ethylene glycol (EG). After being thawed, they were washed in minimum essential medium with or without 0.3 M sucrose. Histological analysis of follicle i...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-006-0193-5
更新日期：2006-09-01 00:00:00
abstract：:The ultrastructure of the sinus gland of the fiddler crab, Uca pugnax, was investigated and found to be similar to that in other crustaceans. Five types of neurosecretory axon terminals were tentatively identified on the basis of the size, shape, and electron density of granules within the axons. Release of neuro-secr...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00222805
更新日期：1975-12-29 00:00:00
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journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-004-1046-8
更新日期：2005-05-01 00:00:00
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journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-016-2386-x
更新日期：2016-08-01 00:00:00
abstract：:The solute carrier (SLC) group of membrane transport proteins includes about 400 members organized into more than 50 families. The SLC family that comprises nucleoside-sugar transporters is referred to as SLC35. One of the members of this family is SLC35F1. The function of SLC35F1 is still unknown; however, recent stu...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-019-03008-8
更新日期：2019-08-01 00:00:00
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journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-002-0538-7
更新日期：2002-05-01 00:00:00
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journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00215191
更新日期：1986-01-01 00:00:00
abstract：:Call-Exner bodies are present in ovarian follicles of a range of species including human and rabbit, and in a range of human ovarian tumors. We have also found structures resembling Call-Exner bodies in bovine preantral and small antral follicles. Hematoxylin and eosin staining of single sections of bovine ovaries has...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s004410051298
更新日期：1999-05-01 00:00:00
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journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-005-0046-7
更新日期：2006-01-01 00:00:00
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journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-013-1660-4
更新日期：2013-09-01 00:00:00
abstract：:Live Merkel cells in the skin and hair follicles are known to incorporate a fluorescence dye, quinacrine, which has been utilized to identify and dissect the cells for experiments. Quinacrine fluorescence of the cells is, however, quickly lost and quinacrine-stained Merkel cells soon become difficult to identify in ti...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-002-0688-7
更新日期：2003-03-01 00:00:00
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journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00234326
更新日期：1979-11-01 00:00:00
abstract：:Transforming growth factor beta (TGF-beta) is a major member of a cytokine family with pluripotent biological activity. In the liver, TGF-beta has pathophysiological significance with respect to hepatic fibrogenesis, regulation of liver cell growth, tumor development, and induction of hepatocellular apoptosis. We show...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s004410050740
更新日期：1997-01-01 00:00:00
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journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00221474
更新日期：1989-09-01 00:00:00
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journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00216742
更新日期：1981-01-01 00:00:00
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journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-002-0523-1
更新日期：2002-04-01 00:00:00
abstract：:Notch signaling is evolutionarily conserved from Drosophila to human. It plays critical roles in neural stem cell maintenance and neurogenesis in the embryonic brain as well as in the adult brain. Notch functions greatly depend on careful regulation and cross-talk with other regulatory mechanisms. Deregulation of Notc...
journal_title：Cell and tissue research
pub_type： 杂志文章,评审
doi：10.1007/s00441-017-2641-9
更新日期：2018-01-01 00:00:00
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journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00219771
更新日期：1977-08-26 00:00:00
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journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-001-0503-x
更新日期：2002-03-01 00:00:00
abstract：:Scanning electrom microscopy of the ventricular surface of the pars ventralis of the tuber cinereum of the frog Rana temporaria shows that it can be divided in (1) a dorsolateral area, characterized by the presence of very numerous large, solid, bulbous protrusions (2) a medial area, where the large bulbous structures...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00231997
更新日期：1975-05-27 00:00:00
abstract：:Carotid bodies of ducks show no detectable changes in ultrastructure up to periods of four weeks following the removal of 2-3 cm of the cervical vagus (decentralization). This indicates that the majority, and possibily all the nerves terminating on the glomus cells are afferent (sensory) in nature. These nerve endings...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00218494
更新日期：1975-11-19 00:00:00
abstract：:The true surface of rabbit spinal ganglion neurons has been made directly accessible to scanning electron-microscope observation after removal of both the connective tissue and satellite cells that normally cover it. The neuronal surface is characterized by a profusion of slender projections whose shapes have been det...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00297502
更新日期：1990-04-01 00:00:00
abstract：:The enteric nervous system (ENS) controls gastrointestinal functions. In large mammals' intestine, it comprises an inner (ISP) and outer (OSP) submucous plexus and a myenteric plexus (MP). This study quantifies enteric neurons in the ISP, OSP, and MP of the pig ascending (AC) and descending colon (DC) using the HuC/D,...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-020-03286-7
更新日期：2020-09-23 00:00:00
abstract：:Proteins participating in vesicular docking and fusion have been identified in the nervous system. Such proteins appear to be important for the molecular regulation of exocytosis also in non-neuronal cells. The enterochromaffin-like (ECL) cells of the gastric acid-secreting (oxyntic) mucosa secrete histamine and chrom...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s004410050960
更新日期：1997-12-01 00:00:00
