Abstract:
:This study investigated whether cytokines and colony-stimulating factors can predict prognosis in patients with postoperative multiple organ failure (MOF). We evaluated 14 patients with postoperative MOF who underwent operation for cardiovascular disease. Seven patients recovered from MOF (survivors) and seven did not recover and died (nonsurvivors). The white blood cell (WBC) count, granulocyte colony-stimulating factor, monocytic colony-stimulating factor, interleukin-6 (IL-6), and IL-8 were measured on the day the patients were judged to be in MOF and each week thereafter until the patients recovered or died. Survivors and nonsurvivors were equivalent in terms of age, gender, proportion of use of extracorporeal circulation, operation time, volume of blood transfusion, time from operation to the onset of MOF, the MOF score, proportion of bacteremia, duration of MOF, and number of failed organs. The mean duration of MOF was less than 2 weeks in both groups; therefore the measurements were compared on the first day of MOF and 1 week later. No significant differences between the two groups in terms of WBC counts, colony-stimulating factors, and IL-6 levels were noted. However, the serum level of IL-8 was significantly higher in nonsurvivors than in survivors. Patients with a high serum levels of IL-8 at the time of MOF had a poor prognosis.
journal_name
World J Surgjournal_title
World journal of surgeryauthors
Hamano K,Gohra H,Noda H,Katoh T,Fujimura Y,Zempo N,Esato Kdoi
10.1007/s002689900520subject
Has Abstractpub_date
1998-10-01 00:00:00pages
1077-81issue
10eissn
0364-2313issn
1432-2323journal_volume
22pub_type
杂志文章abstract:BACKGROUND:Efficient DNA damage repair by MutL-homolog DNA mismatch repair (MMR) enzymes, MLH1, MLH3, PMS1 and PMS2, are required to maintain thyrocyte genomic integrity. We hypothesized that persistent oxidative stress and consequent transcriptional dysregulation observed in thyroid follicles will lead to MMR deficien...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-017-4299-6
更新日期:2018-02-01 00:00:00
abstract:BACKGROUND:The only potential cure for neuroendocrine tumors (NETs) is operative resection, which may also offer a survival benefit for advanced disease. We aimed to assess the role of 68Ga-DOTATATE PET/CT in preoperative planning and compared its performance to CT with IV contrast and MRI with Eovist®, for abdominal N...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-019-05216-3
更新日期:2020-02-01 00:00:00
abstract::During the course of tumor progression the differentiated morphologic and functional characteristics of differentiated thyroid carcinomas (DTC) disappear. This corresponds to more aggressive growth, metastatic spread, and loss of iodine uptake. Experimental data give strong evidence that differentiated functions of io...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s002689900436
更新日期:1998-06-01 00:00:00
abstract:BACKGROUND:The prognosis of intrahepatic cholangiocarcinoma (ICC) remains poor despite improvements in treatment and post-operative clinical management. We review our experiences and evaluate our current surgical approaches by comparing patients from two consecutive treatment periods. METHODS:One hundred forty-four pa...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-016-3583-1
更新日期:2016-09-01 00:00:00
abstract:BACKGROUND:Patients with stage II colorectal cancer (CRC) have a higher risk of recurrence when they have certain risk factors, including clinical and pathological patterns. However, as the prognostic role of molecular patterns for stage II disease is still unclear, this study aimed to investigate it. METHODS:A total ...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-019-05158-w
更新日期:2019-12-01 00:00:00
abstract:BACKGROUND:The efficacy and the indications of resection of synchronous or metachronous hepatic and pulmonary metastases from colorectal cancer (CRC) are controversial. This study retrospectively reviewed the cases of CRC patients who underwent both liver and lung resection to define the appropriate indications for sur...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-012-1708-8
更新日期:2012-11-01 00:00:00
abstract:BACKGROUND:The psychiatric population has been reported to be accompanied with a higher morbidity and mortality in several situations. However, little is known about the effect of co-morbid psychiatric disorders on surgical risk during major digestive surgery for malignancies. Our purpose in the present study, therefor...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-007-9267-0
更新日期:2007-12-01 00:00:00
abstract::Knowledge of how factors related to esophageal cancer resection affect long-term quality of life after surgery is scarce, and no population-based studies are available. Therefore, we conducted a Swedish nationwide, prospective, population-based study of how esophageal surgery-related factors influence quality of life ...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-005-7887-9
更新日期:2005-07-01 00:00:00
abstract::This paper describes a model humanitarian mission to Guyana; it illustrates the value of excellent ongoing care in collaboration with local physicians and surgeons, cooperation with local government and medical officials, and frequent periodic follow-up missions (always to the same hospital, working with the same staf...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-015-3049-x
更新日期:2015-08-01 00:00:00
abstract:INTRODUCTION:This study assesses the incidence of missed pelvic injuries in the pre-hospital setting. METHODS:All blunt trauma patients (ISS ≥ 9) with pre-hospital suspicion of and/or radiologically proven pelvic fracture documented in the TraumaRegister DGU® (TR-DGU) of the German Trauma Society DGU (2002-2011) were ...
journal_title:World journal of surgery
pub_type: 杂志文章,多中心研究
doi:10.1007/s00268-016-3647-2
更新日期:2016-12-01 00:00:00
abstract::Postoperative complications in patients with obstructive jaundice remain increased when associated with endotoxemia and the inflammatory response due to gut barrier failure. Administration of glutamine has been proposed to maintain the integrity of the gut mucosa and thus reduce bacterial translocation (BT), but the e...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-005-7721-4
更新日期:2005-10-01 00:00:00
abstract:BACKGROUND:The 6th edition TNM staging (TNM-6) for hepatocellular carcinoma (HCC) has been recommended. However, its superiority, in contrast to the previous 5th edition (TNM-5), has not been fully recognized. Besides, tumor differentiation was not included. The current study was designed to compare the value of these ...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-008-9615-8
更新日期:2008-08-01 00:00:00
abstract::Endoscopic management of polypoid early colonic cancer (malignant polyps and polypoid carcinomas) is no longer controversial. When the endoscopist is satisfied that excision is complete and histology is "favorable" (a resection margin of 2 mm and well or moderately well differentiated tumor), surgery is unnecessary. W...
journal_title:World journal of surgery
pub_type: 杂志文章,评审
doi:10.1007/s002680010144
更新日期:2000-09-01 00:00:00
abstract::Jaundice in patients of advanced carcinoma of the gallbladder requires palliation for the distressing symptoms of pruritus and cholangitis. Intrahepatic segment III duct cholangiojejunostomy is a means for alleviating the obstruction with malignant porta block. The authors reviewed their experience with this procedure...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s002689900319
更新日期:1997-10-01 00:00:00
abstract::Nineteen consecutive patients receiving renal transplants underwent prospective evaluation of their calcium homeostasis for 1 year after transplantation to characterize indices of hyperparathyroidism (HPT) amelioration. All but one underwent dialysis, and six had vitamin D supplementation before grafting. The rapid fa...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s002689900446
更新日期:1998-06-01 00:00:00
abstract:BACKGROUND:Better prognostic markers are needed for pancreatic endocrine tumors. Survivin is an apoptosis inhibitor that is suggested to have a negative prognostic impact in several tumor types. Contradictory data exist, especially regarding the significance of a nuclear versus cytoplasmic location of survivin. The pro...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-011-1345-7
更新日期:2012-06-01 00:00:00
abstract:BACKGROUND:Enhanced recovery (ERAS) guidelines do not differentiate between left- and right-sided colectomies, but differences in recovery have been reported for the two procedure types. We aimed to compare compliance with the ERAS protocol and outcomes after right versus left colectomy. METHODS:Between June 2011 and ...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-016-3563-5
更新日期:2016-10-01 00:00:00
abstract::From the earliest description of dysphagia relieved by dilatation with a whalebone in 1674 we have witnessed the evolution of esophageal function testing from the conventional manometry to the high-resolution manometry (HRM) and esophageal topography pressure plotting that have led to the revised Chicago classificatio...
journal_title:World journal of surgery
pub_type: 历史文章,杂志文章
doi:10.1007/s00268-014-2939-7
更新日期:2015-07-01 00:00:00
abstract:OBJECTIVE:Mirizzi syndrome (MS) is an uncommon presentation of cholelithiasis. This study aims to find the incidence and analyze the outcome of management of this condition at Riyadh Medical Complex (RMC) with particular reference to diagnostic methods and outcome of surgical treatment. METHODS:Retrospective study on ...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-005-0100-3
更新日期:2005-12-01 00:00:00
abstract:BACKGROUND:Recurrent renal hyperparathyroidism (HPT) is a serious problem after parathyroidectomy (PTx). We evaluated the frequency of graft-dependent recurrent HPT and the clinical outcomes after removal of the autograft. METHODS:Between March 1980 and January 2009, 2660 patients underwent total PTx with forearm auto...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-010-0412-9
更新日期:2010-06-01 00:00:00
abstract::Pectus excavatum (PE) is one of the most common anomalies of childhood. It occurs in approximately 1 in every 400 births, with males afflicted 5 times more often than females. PE is usually recognized in infancy, becomes much more severe during adolescent growth years, and remains constant throughout adult life. Sympt...
journal_title:World journal of surgery
pub_type: 社论,评审
doi:10.1007/s00268-003-7025-5
更新日期:2003-05-01 00:00:00
abstract:BACKGROUND:Small intestinal neuroendocrine neoplasms (SI-NEN) are rare, and only about 40% of patients are diagnosed without distant metastases. Aim of the study was to identify prognostic factors in patients with potentially curative resected locoregional SI-NEN. METHODS:Patients with curative resected locoregional S...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-020-05884-6
更新日期:2021-01-08 00:00:00
abstract:BACKGROUND:Surgical disease burden falls disproportionately on individuals in low- and middle-income countries. These populations are also the least likely to have access to surgical care. Understanding the barriers to access in these populations is therefore necessary to meet the global surgical need. METHODS:Using g...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-016-3765-x
更新日期:2017-03-01 00:00:00
abstract::Pancreas transplantation has emerged as the single most effective way to achieve normal glucose homeostasis inpatients with type I insulin-dependent diabetes mellitus. Optimal immunosuppressive strategies for pancreas transplantation continue to evolve with the use of newer, more potent immunosuppressive agents,partic...
journal_title:World journal of surgery
pub_type: 杂志文章,评审
doi:10.1007/s00268-001-0207-0
更新日期:2002-02-01 00:00:00
abstract::The primal need for nutrients is satisfied by mechanisms for sensing internal stores and detecting food; ATP is the most primitive signal. With increasing density of sensory neurons and glia (the primordial brain) and the emergence of autonomic neural activity throughout the endoderm, transmitters and other signaling ...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-009-0138-8
更新日期:2009-10-01 00:00:00
abstract:BACKGROUND:A small remnant liver volume is an important risk factor for posthepatectomy liver failure and can be predicted accurately by computed tomography (CT) volumetry using radiologic image analysis software. Unfortunately, this software is expensive and usually requires support by a radiologist. ImageJ is a freel...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-007-9197-x
更新日期:2007-11-01 00:00:00
abstract::In a double-blind placebo-controlled study we investigated the effect of recombinant human erythropoietin (r-HuEPO), on the perioperative hemoglobin concentration and the use of blood transfusions in patients undergoing elective colorectal surgery with a preoperative hemoglobin level =8.5 mmol/L. Altogether 100 were...
journal_title:World journal of surgery
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1007/s002689900561
更新日期:1999-01-01 00:00:00
abstract:BACKGROUND:Intestinal epithelial cell apoptosis has been reported in sepsis as a mechanism of organ failure. The aim of this study was to clarify the role of apoptosis-regulating proteins (bcl-2, bax, cytochrome-c, and caspase-8) in septic rats by studying their expression in gastric and intestinal epithelial cells. M...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-005-0742-1
更新日期:2007-04-01 00:00:00
abstract::Hereditary breast cancers, mainly due to BRCA1 and BRCA2 mutations, account for only 5-10% of this disease. The threshold for genetic testing is a 10% likelihood of detecting a mutation, as determined by validated models such as BOADICEA and Manchester Scoring System. A 90-95% reduction in breast cancer risk can be ac...
journal_title:World journal of surgery
pub_type: 杂志文章,评审
doi:10.1007/s00268-018-04897-6
更新日期:2019-05-01 00:00:00
abstract:BACKGROUND:Geriatric collaborative care models improve postoperative outcomes for older adults. However, there are limited data exploring how preoperative geriatric assessment may affect surgical cancellations. METHODS:This is a single-center retrospective cohort analysis. Patients enrolled in the Perioperative Optimi...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-020-05772-z
更新日期:2021-01-01 00:00:00