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Histochemical localization of glycoconjugates on microglial cells in Alzheimer's disease brain samples by using Abrus precatorius, Maackia amurensis, Momordica charantia, and Sambucus nigra lectins.

Abstract：

:Four lectins (Abrus precatorius (APA), Maackia amurensis (MAA), Momordica charantia (MCA) and Sambucus nigra (SNA)) have been used to identify glycohistochemically the microglial cells (MGC) activation in autoptic brain samples from Alzheimer's disease (AD) subjects. Three of these lectins (APA, MAA and MCA) have utilized as microglial cell markers for the first time. The identification of new markers for the study of MGC is very important to better understand the role of these type of cells in the metabolic/dismetabolic control of betaA4 in AD which still represents a vexata questio.

journal_name

Exp Neurol

journal_title

Experimental neurology

authors

Zambenedetti P,Giordano R,Zatta P

doi

10.1006/exnr.1998.6862

subject

Has Abstract

pub_date

1998-09-01 00:00:00

pages

167-71

issue

1

eissn

0014-4886

issn

1090-2430

pii

S0014-4886(98)96862-5

journal_volume

153

pub_type

杂志文章

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