Abstract:
UNLABELLED:Aim of our study was to evaluate Doppler renal blood flow velocity in asphyxiated neonates and to correlate renal function to Doppler findings. Doppler renal blood flow velocity was evaluated in 23 severely asphyxiated neonates born at a gestational age > 32 weeks and compared to our standard Doppler data obtained in 25 healthy neonates comparable for gestational age and birth weight. Renal Doppler ultrasound was performed on the 1st and 3rd days of life. Renal function was investigated in the first 2 weeks of life. Asphyxiated neonates showed mean values of systolic velocity and mean velocity significantly reduced (P < 0.001) compared with our standard Doppler values on the 1st day of life. Seven out of the 23 asphyxiated neonates were affected by acute renal failure and 14 showed no renal involvement. Two neonates were oliguric but did not develop acute renal failure. On the 1st day of life, neonates with acute renal failure had significantly lower mean values of systolic velocity and mean velocity than the asphyxiated neonates without renal involvement (P < 0.01). All 7 neonates affected by acute renal failure showed a systolic velocity more than 2SD below the mean standard value, while only 4 of the 16 asphyxiated neonates (25%) without acute renal failure had low systolic velocity values on the 1st day of life. Doppler velocities in asphyxiated neonates were similar to standard values on the 3rd day of life. Renal failure recovered before the 11th day of life in all cases. CONCLUSION:Our findings indicate that decreased Doppler renal flow systolic velocity observed in asphyxiated neonates on the st day of life is a useful predictive index for subsequent development of acute renal failure, with 100% sensitivity and 63.6% specificity.
journal_name
Eur J Pediatrjournal_title
European journal of pediatricsauthors
Luciano R,Gallini F,Romagnoli C,Papacci P,Tortorolo Gdoi
10.1007/s004310050905subject
Has Abstractpub_date
1998-08-01 00:00:00pages
656-60issue
8eissn
0340-6199issn
1432-1076journal_volume
157pub_type
杂志文章abstract:UNLABELLED:Delta1-pyrroline-5-carboxylate synthase (P5CS) catalyses the reduction of glutamate to Delta1-pyrroline-5-carboxylate, a critical step in the biosynthesis of proline, ornithine and arginine. Recently, we reported a newly recognised inborn error due to deficiency of P5CS in two sibs, one presenting at birth w...
journal_title:European journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s00431-004-1545-3
更新日期:2005-01-01 00:00:00
abstract:UNLABELLED:The purpose of this study was to determine the effect of low birth weight at term on serum lipoproteins. Lipid and apolipoprotein (apo) contents were investigated in cord sera of small-for-gestational-age (SGA) newborns at term (2290 g +/- 33 g) and compared with those of appropriate-for-gestational-age (AGA...
journal_title:European journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s004310050820
更新日期:1998-04-01 00:00:00
abstract::Direct measurements of parathyroid activity are available in only small numbers of children with vitamin D deficiency rickets (VDR). Therefore serum immunoreactive parathyroid hormone (iPTH) and the urinary cyclic adenosine-3',5'-monophosphate excretion (UcAMP) were measured together with other important indices of ca...
journal_title:European journal of pediatrics
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更新日期:1984-01-01 00:00:00
abstract:UNLABELLED:Although bacterial colonisation of bronchi may occur from early childhood onwards, infections extending beyond the lungs are uncommon in patients with cystic fibrosis. A 12-year-old boy with cystic fibrosis, receiving oral corticosteroids for 3 weeks because of allergic bronchopulmonary aspergillosis, experi...
journal_title:European journal of pediatrics
pub_type: 杂志文章
doi:10.1007/pl00008408
更新日期:2000-09-01 00:00:00
abstract:BACKGROUND:Human immunodeficiency virus type 1 (HIV-1) infected children treated with highly active antiretroviral therapy (HAART) may develop a significant reduction of plasma viremia associated with an increase in CD4+ T-cell counts. Functional capacity of this reconstituted immune system in response to recall antige...
journal_title:European journal of pediatrics
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更新日期:2007-01-01 00:00:00
abstract::A combination of humoral immunodeficiency and isolated growth hormone deficiency was observed in a girl with Mulibrey nanism. The humoral immunodeficiency consisted of subnormal concentration of serum IgG, in particular IgG2 and IgG4, and low concentration of serum IgM. Serum IgA and IgD were elevated, IgE was absent....
journal_title:European journal of pediatrics
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更新日期:1993-06-01 00:00:00
abstract::Urinary tract infection (UTI) is a common cause of sepsis in infants. Premature infants hospitalized at a neonatal intensive care unit often have risk factors for infection. In this group, the risk of UTI is not clearly known, and guidelines for urine analysis are not unanimous. We aimed to identify the risk of UTI in...
journal_title:European journal of pediatrics
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doi:10.1007/s00431-017-3030-9
更新日期:2018-01-01 00:00:00
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journal_title:European journal of pediatrics
pub_type: 临床试验,杂志文章
doi:10.1007/s00431-011-1486-6
更新日期:2012-01-01 00:00:00
abstract::Primary ciliary dyskinesia (PCD) is an inherited disease related to ciliary dysfunction, with heterogeneity in clinical presentation and in ciliary ultrastructural defect. Our study intended to determine if there are phenotypic differences in patients with PCD based on ciliary ultrastructural abnormality. In this retr...
journal_title:European journal of pediatrics
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abstract::Effective management of pain remains an important indicator of the quality of care provided to neonates. Since the review of McIntosh in this journal over a decade ago, an extensive number of papers on assessment, prevention, and treatment of pain have been reported. In addition, preclinical insights into neurodevelop...
journal_title:European journal of pediatrics
pub_type: 杂志文章,评审
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更新日期:2009-07-01 00:00:00
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journal_title:European journal of pediatrics
pub_type: 杂志文章
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更新日期:2014-04-01 00:00:00
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journal_title:European journal of pediatrics
pub_type: 杂志文章
doi:10.1007/BF01954489
更新日期:1994-10-01 00:00:00
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journal_title:European journal of pediatrics
pub_type: 杂志文章,评审
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更新日期:2002-10-01 00:00:00
abstract::Early diagnosis and treatment of phenylketonuria (PKU) in Poland was started in 1965, initially on a voluntary and then on a obligatory basis. Guthrie tests have been used for newborn screening. For confirmation of diagnosis changing with time methods of blood phenylalanine (Phe) and tyrosine estimation were used. In ...
journal_title:European journal of pediatrics
pub_type: 杂志文章
doi:10.1007/pl00014250
更新日期:1996-07-01 00:00:00
abstract::The aim of the study was to assess the epidemiology and risk factors of adrenal crises (AC) in children with adrenal insufficiency (AI). Children diagnosed with AI between 1990 and 2017 at four Israeli pediatric endocrinology units were studied. Demographic and clinical data were retrieved retrospectively from their f...
journal_title:European journal of pediatrics
pub_type: 杂志文章
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journal_title:European journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s00431-014-2440-1
更新日期:2015-05-01 00:00:00
abstract::This paper describes the percentile curves for red blood cell (RBC) count, Hb, mean corpuscular volume (MCV) and mean corpuscular haemoglobin (MCH) values of beta zero-thalassaemia heterozygotes during infancy, childhood and adolescence. Hb values were about 2 g/dl below those of normal controls with a progressive inc...
journal_title:European journal of pediatrics
pub_type: 杂志文章
doi:10.1007/BF02093721
更新日期:1991-04-01 00:00:00
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journal_title:European journal of pediatrics
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journal_title:European journal of pediatrics
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journal_title:European journal of pediatrics
pub_type: 杂志文章,多中心研究
doi:10.1007/s004310050636
更新日期:1997-06-01 00:00:00
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journal_title:European journal of pediatrics
pub_type: 临床试验,杂志文章,多中心研究
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更新日期:2018-07-01 00:00:00
abstract::Three sibs with an inherited form of male pseudohermaphroditism are described. They were all born with ambiguous external genitalia but no diagnosis of a possible enzyme defect was made during childhood. First seen at the ages of 16, 14 and 10 years respectively, they were investigated in order to establish the pathog...
journal_title:European journal of pediatrics
pub_type: 杂志文章
doi:10.1007/BF00441984
更新日期:1988-06-01 00:00:00
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journal_title:European journal of pediatrics
pub_type: 杂志文章
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更新日期:2012-01-01 00:00:00
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journal_title:European journal of pediatrics
pub_type: 杂志文章,多中心研究
doi:10.1007/s00431-015-2566-9
更新日期:2015-11-01 00:00:00
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journal_title:European journal of pediatrics
pub_type: 杂志文章
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更新日期:2020-01-01 00:00:00
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journal_title:European journal of pediatrics
pub_type: 杂志文章
doi:10.1007/BF02429048
更新日期:1986-12-01 00:00:00
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journal_title:European journal of pediatrics
pub_type: 杂志文章
doi:10.1007/BF00493539
更新日期:1978-04-20 00:00:00
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journal_title:European journal of pediatrics
pub_type: 杂志文章,评审
doi:10.1007/BF02072628
更新日期:1991-07-01 00:00:00
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pub_type: 杂志文章
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更新日期:2010-04-01 00:00:00