The IGF system during fetal-placental development of the mouse.

Abstract:

:Insulin-like growth factors (IGF-I and -II) promote cellular mitosis and differentiation and have been implicated in fetal and placental growth. Together with the IGF receptors and IGF binding proteins (IGFBPs) they form a complex network, with tissue specific activity. This review will discuss the data generated to elucidate the functions of the IGF system during mouse development.

journal_name

Mol Cell Endocrinol

authors

van Kleffens M,Groffen C,Lindenbergh-Kortleve DJ,van Neck JW,González-Parra S,Dits N,Zwarthoff EC,Drop SL

doi

10.1016/s0303-7207(98)00041-0

subject

Has Abstract

pub_date

1998-05-25 00:00:00

pages

129-35

issue

1-2

eissn

0303-7207

issn

1872-8057

pii

S0303-7207(98)00041-0

journal_volume

140

pub_type

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