Abstract:
:Fifteen children with protein-energy malnutrition and eight healthy children between the ages of 6 months and 60 months were studied for blood glucose and serum insulin levels in the fasting state and 120 minutes following oral glucose load. The measurements were repeated after normalization of the body weight following 6 weeks of nutritional rehabilitation. The fasting blood glucose increased significantly in the post-treatment period and became comparable to the control value. The abnormal blood glucose response to oral glucose load also normalized. The serum insulin level rose significantly (p < 0.001) in the post-treatment period but failed to normalize. The response to oral glucose load was similar. The observed lower insulin response, despite normoglycemia, after 6 weeks of nutritional rehabilitation indicates persistence of hormonal imbalance which may need a longer duration of rehabilitation for full recovery.
journal_name
J Trop Pediatrjournal_title
Journal of tropical pediatricsauthors
Das BK,Ramesh J,Agarwal JK,Mishra OP,Bhatt RPdoi
10.1093/tropej/44.4.230subject
Has Abstractpub_date
1998-08-01 00:00:00pages
230-1issue
4eissn
0142-6338issn
1465-3664journal_volume
44pub_type
临床试验,杂志文章abstract::The composition (total solids, total protein, casein, coagulable proteins, lactose, fat, and ash) and mineral content (calcium, phosphorus, sodium, potassium, magnesium, zinc, and copper) of human milk was estimated longitudinally for the first year of lactation. Concentration of various nutrients, except zinc and cop...
journal_title:Journal of tropical pediatrics
pub_type: 杂志文章
doi:10.1093/tropej/35.3.126
更新日期:1989-06-01 00:00:00
abstract::The aim of this study was to compare the neonatal outcomes of babies with birthweights < 10th centile to those with birthweights > or = 10th centile with a gestational age of 28-34 weeks. This retrospective hospital-based study was performed at a tertiary referral centre. All women with early, severe pre-eclampsia, ma...
journal_title:Journal of tropical pediatrics
pub_type: 杂志文章
doi:10.1093/tropej/49.3.178
更新日期:2003-06-01 00:00:00
abstract::Haemolysin production (Hly) and mannose-resistant haemagglutination induction (MRHA) of human (H), bovine (B), and both (HB) erythrocytes was investigated in strains of E. coli isolated from 142 cases of children with diarrhoea aged 0-36 months. Haemolysin production was more frequent in strains isolated from children...
journal_title:Journal of tropical pediatrics
pub_type: 杂志文章
doi:10.1093/tropej/39.3.183
更新日期:1993-06-01 00:00:00
abstract::Multiple dose measles vaccination was applied in Gweru, Zimbabwe in 1990-1996. This included (a) a vaccine administered to children at 9 months of age and revaccination of the same children at any point between the ages of 12 and 23 months, and (b) a single mass vaccination campaign targeted at children aged 12-119 mo...
journal_title:Journal of tropical pediatrics
pub_type: 杂志文章
doi:10.1093/tropej/47.6.335
更新日期:2001-12-01 00:00:00
abstract::Congenital abnormalities are important causes of morbidity and mortality in children and significantly add to the burdens on healthcare in developing countries. Unfortunately, there remains a paucity of information on congenital birth defects in most developing countries. This is a 4-year prospective study that assess...
journal_title:Journal of tropical pediatrics
pub_type: 杂志文章
doi:10.1093/tropej/fmx067
更新日期:2018-08-01 00:00:00
abstract::Lymphocyte subsets, activation markers and apoptosis were assessed in 20 HIV-exposed noninfected (ENI) children born to HIV-infected women who were or not exposed to antiretroviral (ARV) drugs during pregnancy and early infancy. ENI children and adolescents were aged 6-18 years and they were compared to 25 age-matched...
journal_title:Journal of tropical pediatrics
pub_type: 杂志文章
doi:10.1093/tropej/fmq024
更新日期:2010-12-01 00:00:00
abstract:PURPOSE:To assess whether the key informant method (KIM) is an effective method to identify children with disabling sensory or physical impairments, or epilepsy (tonic-clonic seizures), in a low-income setting. METHODS:In one subdistrict each, the Key Informants (KIs) were trained to recognize children with visual imp...
journal_title:Journal of tropical pediatrics
pub_type: 杂志文章
doi:10.1093/tropej/fmr094
更新日期:2012-08-01 00:00:00
abstract::Based on reports of parasite resistance and on World Health Organization recommendation, chloroquine was replaced with the artemisinin-based combination therapies (ACTs) as the first choice of drugs for the treatment of uncomplicated malaria. Disuse of chloroquine led to restoration of drug-sensitive parasite to some ...
journal_title:Journal of tropical pediatrics
pub_type: 杂志文章
doi:10.1093/tropej/fmaa089
更新日期:2020-12-27 00:00:00
abstract::Missed opportunities and inappropriately time immunization substantially reduced the coverage achieved in Mozambique and Guinea Conakry. During coverage surveys in Mozambique, we noted dates of attendance at a health facility for growth monitoring or vaccination, and in Conakry we also abstracted dates of curative car...
journal_title:Journal of tropical pediatrics
pub_type: 杂志文章
doi:10.1093/tropej/37.4.153
更新日期:1991-08-01 00:00:00
abstract::Most bacterial infections are caused by organisms that have already colonized the host. Bacterial attachment to pharyngeal cells and proliferation may be necessary to infect the lower respiratory tract or middle ear. We investigated the incidence of pathogenic bacteria isolated from the throat of healthy infants with ...
journal_title:Journal of tropical pediatrics
pub_type: 杂志文章
doi:10.1093/tropej/45.3.173
更新日期:1999-06-01 00:00:00
abstract::The objectives of this study were to determine causes of admission to a district hospital neonatal nursery; to describe outcomes; and to determine risk factors for these outcomes. The study was based at the neonatal nursery of Hlabisa hospital, KwaZulu/Natal; 149 consecutive admissions to the nursery between May and N...
journal_title:Journal of tropical pediatrics
pub_type: 杂志文章
doi:10.1093/tropej/45.2.76
更新日期:1999-04-01 00:00:00
abstract::The etiological spectrum of 558 children (< 16 years) with partial seizures seen in a university hospital in south India, was analysed using syndromic classification proposed by the International League Against Epilepsy (ILAE). Partial seizures accounted for 57 per cent of childhood epilepsies. Idiopathic localization...
journal_title:Journal of tropical pediatrics
pub_type: 杂志文章
doi:10.1093/tropej/46.4.202
更新日期:2000-08-01 00:00:00
abstract::Awareness of cardiac involvement in dengue infection has potentially valuable management implications. To determine the prevalence of myocarditis in dengue severity, we conducted prospective study of paediatric dengue illness at Dr. Sardjito General Hospital, a tertiary hospital in Yogyakarta, Indonesia, from period o...
journal_title:Journal of tropical pediatrics
pub_type: 杂志文章
doi:10.1093/tropej/fmz020
更新日期:2019-12-01 00:00:00
abstract:INTRODUCTION:Early diagnosis and treatment is necessary to prevent HIV-infected infants progressing to AIDS. Antibody testing is not confirmatory before the age of 18 months and PCR not widely available in resource-poor settings. We studied the accuracy of CD4(+) T-lymphocyte count, CD4% and CD4/CD8 ratio as surrogate ...
journal_title:Journal of tropical pediatrics
pub_type: 杂志文章
doi:10.1093/tropej/fmr102
更新日期:2012-10-01 00:00:00
abstract::Symptoms from the genitourinary system are unusual in Kawasaki disease (KD). Renal involvement is even rarer and it is confirmed by biopsy when the person is alive. We describe the case of an 11-year-old boy admitted to the hospital complaining about prolonged fever (5 days) and hematuria. His urinalysis showed also p...
journal_title:Journal of tropical pediatrics
pub_type: 杂志文章
doi:10.1093/tropej/fmn065
更新日期:2009-02-01 00:00:00
abstract::The cornerstone of emergency management of sepsis is early, goal-directed therapy. The purpose of this study was to evaluate the effect of intraosseous (IO) vs. intravenous (IV) access for resuscitation of patients with septic shock admitted to pediatric intensive care unit. This prospective interventional randomized ...
journal_title:Journal of tropical pediatrics
pub_type: 杂志文章,随机对照试验
doi:10.1093/tropej/fmx061
更新日期:2018-04-01 00:00:00
abstract:BACKGROUND:The purpose of this study was to evaluate left and right ventricular functions by using the Doppler myocardial performance index (MPI), in children with sickle cell anemia (SCA). METHODS:We examined 32 patients with SCA and 30 age-matched healthy children. Echocardiography and Doppler examinations were comp...
journal_title:Journal of tropical pediatrics
pub_type: 杂志文章
doi:10.1093/tropej/fmp094
更新日期:2010-06-01 00:00:00
abstract::Cardiac complications of 32 children with scorpion envenomation, during a 1-year period from August 1990 to August 1991 were studied. Sixteen children (50 per cent) were diagnosed as having myocarditis; of these in four children the presentation was subclinical. ECG changes were seen in 63 per cent of children envenom...
journal_title:Journal of tropical pediatrics
pub_type: 杂志文章
doi:10.1093/tropej/41.6.338
更新日期:1995-12-01 00:00:00
abstract::We reported the case of a boy who fled from Chechnya to Belgium. He was diagnosed with a human immune deficiency virus (HIV)/Visceral leishmaniasis (VL) coinfection. In both countries, the prevalence of HIV-infected children is low and VL is not endemic. Migration of people results in confrontation with diseases that ...
journal_title:Journal of tropical pediatrics
pub_type: 杂志文章
doi:10.1093/tropej/fmr024
更新日期:2011-12-01 00:00:00
abstract:OBJECTIVE:To find the relationship between vitamin-D levels and late-onset sepsis (LOS) in term neonates. METHODS:This case-control study was conducted in neonatal intensive care unit of a tertiary care teaching institution in central India. Full-term neonates with culture-proven LOS were taken as cases. Maternal and ...
journal_title:Journal of tropical pediatrics
pub_type: 杂志文章
doi:10.1093/tropej/fmz021
更新日期:2019-12-01 00:00:00
abstract::To describe the perspectives of pediatricians from a tertiary care center from India on end-of-life (EOL) care issues, a standardized anonymous questionnaire was administered, which included questions regarding attitudes towards withdrawal/withholding of life-sustaining treatment in children and neonates at the EOL, a...
journal_title:Journal of tropical pediatrics
pub_type: 杂志文章
doi:10.1093/tropej/fmn009
更新日期:2008-08-01 00:00:00
abstract::A total of 220 enteroadherent Escherichia coli were identified from 729 Egyptian children with diarrhea using the HEp-2 adherence assay. Enteropathogenic E.coli (EPEC = 38) was common among children <6 months old and provoked vomiting, while diffuse-adhering E.coli (DAEC = 109) induced diarrheal episodes of short dura...
journal_title:Journal of tropical pediatrics
pub_type: 杂志文章
doi:10.1093/tropej/fmu034
更新日期:2014-10-01 00:00:00
abstract::Burkitt's lymphoma is the most common childhood cancer in Africa. Most prevalent in areas endemic for malaria, the disease, a malignant growth of lymphoid tissue, usually presents itself as a large tumour of the jaw. When first characterized in the 1950s, the lymphoma was thought to spread by some infectious agent. Su...
journal_title:Journal of tropical pediatrics
pub_type: 杂志文章,评审
doi:10.1093/tropej/36.3.114
更新日期:1990-06-01 00:00:00
abstract::Rotavirus vaccination was introduced in Brazil in March 2006. We describe the distribution of rotavirus genotypes in children with acute gastroenteritis in a hospital in Recife, Brazil, during pre- and post-vaccination periods. There was a 43.8% reduction in the proportion of diarrhea episodes due to rotavirus. Nevert...
journal_title:Journal of tropical pediatrics
pub_type: 杂志文章
doi:10.1093/tropej/fmv006
更新日期:2015-06-01 00:00:00
abstract::This study was undertaken with the aim of providing adequate calories for optimal growth in low birth weight (LBW) by fortifying human milk with medium chain triglycerides and sugar. Twenty-one LBW babies with birth weight between 1.0 and 1.75 kg and gestational age 28-36 weeks constituted the study material. They wer...
journal_title:Journal of tropical pediatrics
pub_type: 杂志文章
doi:10.1093/tropej/35.2.77
更新日期:1989-04-01 00:00:00
abstract:OBJECTIVES:The aim of this study was to investigate the relationship between anthropometric characteristics and both geophagy and cognitive function of children. STUDY DESIGN:The study prospectively followed singleton children whose mothers participated in the MiPPAD clinical trial in Allada, Benin, from birth to age ...
journal_title:Journal of tropical pediatrics
pub_type: 杂志文章
doi:10.1093/tropej/fmaa009
更新日期:2020-10-01 00:00:00
abstract::In a prospective study at Sultan Qaboos University Hospital, 95 premature infants with birthweights equal or less than 1500 g were screened for intraventricular haemorrhage (IVH) using cranial ultrasound. Nineteen (20 per cent) were found to have developed IVH. Eight out of fourteen variables studied showed a signific...
journal_title:Journal of tropical pediatrics
pub_type: 杂志文章
doi:10.1093/tropej/43.3.174
更新日期:1997-06-01 00:00:00
abstract::Growth faltering, which may herald protein-energy malnutrition (PEM) usually begins between ages 6 and 12 months. However, arm circumference (AC or MUAC) has mainly been used to screen for PEM between 12 and 60 months of age, when AC is age-independent. This study of 378 infants aged 6-12 months in Pakistan, Nepal, Si...
journal_title:Journal of tropical pediatrics
pub_type: 杂志文章
doi:10.1093/tropej/38.5.240
更新日期:1992-10-01 00:00:00
abstract:Objective:To estimate the prevalence and effects of sepsis-induced myocardial dysfunction (SIMD) in children with septic shock. Methodology:Enrolled children with septic shock (n = 31) and sepsis (n = 30) underwent echocardiography and cardiac troponin-I (cTnI) estimation within first 3 h. SIMD was defined as presence...
journal_title:Journal of tropical pediatrics
pub_type: 杂志文章
doi:10.1093/tropej/fmx105
更新日期:2018-12-01 00:00:00
abstract::Although group A meningococcal disease is a major cause of child morbidity and mortality in sub-Saharan Africa, little is known about vitamin A status and T-cell subpopulations in affected children. A prospective study of vitamin A levels and T-cell subpopulations was conducted in 41 children hospitalized for meningoc...
journal_title:Journal of tropical pediatrics
pub_type: 杂志文章
doi:10.1093/tropej/42.5.287
更新日期:1996-10-01 00:00:00