Blood glucose and serum insulin response in protein-energy malnutrition following nutritional rehabilitation.

Abstract:

:Fifteen children with protein-energy malnutrition and eight healthy children between the ages of 6 months and 60 months were studied for blood glucose and serum insulin levels in the fasting state and 120 minutes following oral glucose load. The measurements were repeated after normalization of the body weight following 6 weeks of nutritional rehabilitation. The fasting blood glucose increased significantly in the post-treatment period and became comparable to the control value. The abnormal blood glucose response to oral glucose load also normalized. The serum insulin level rose significantly (p < 0.001) in the post-treatment period but failed to normalize. The response to oral glucose load was similar. The observed lower insulin response, despite normoglycemia, after 6 weeks of nutritional rehabilitation indicates persistence of hormonal imbalance which may need a longer duration of rehabilitation for full recovery.

journal_name

J Trop Pediatr

authors

Das BK,Ramesh J,Agarwal JK,Mishra OP,Bhatt RP

doi

10.1093/tropej/44.4.230

subject

Has Abstract

pub_date

1998-08-01 00:00:00

pages

230-1

issue

4

eissn

0142-6338

issn

1465-3664

journal_volume

44

pub_type

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