Abstract:
OBJECTIVE:To determine the clinical profile of children with Henoch-Schonlein purpura (HSP). DESIGN:Hospital based descriptive follow-up study. SUBJECTS:45 patients attending the Pediatric Rheumatology and Immunology clinic over the last 4 years. RESULTS:The patients were aged between 2.5-12 years with a male to female ratio of 2:1. All cases had palpable purpura. Gastrointestinal involvement was seen in 38 patients, with abdominal pain in 35 (78%) and lower GI bleed in 21 (47%). Large joint arthritis occurred in 60%. Renal involvement was seen in 14 subjects (31%). Major renal involvement occurred in 9 patients, with nephritic syndrome in 6 and nephrotic syndrome in 3 cases. Five patients had minor urinary abnormalities; 6 patients with major renal involvement and crescentic glomerulonephritis were treated with high dose pulse steroid therapy followed by oral prednisolone and azathioprine for 12-18 months. Normalization of urinary abnormalities occurred in these patients over 4-8 months and presently all are normotensive and off antihypertensive drugs. CONCLUSIONS:HSP in children is a common form of vasculitis. Though short term results in HSP nephritis have been good, long term prognosis in those with major renal involvement would remain guarded.
journal_name
Indian Pediatrjournal_title
Indian pediatricsauthors
Kumar L,Singh S,Goraya JS,Uppal B,Kakkar S,Walker R,Sehgal Ssubject
Has Abstractpub_date
1998-01-01 00:00:00pages
19-25issue
1eissn
0019-6061issn
0974-7559journal_volume
35pub_type
杂志文章abstract::In this cohort study, neurodevelopmental outcome of 20 of 24 surviving very low birth weight infants with sepsis followed up between 2008 and 2009 was compared with 20 control (uninfected infants). We found that plasma interleukin 6 and C reactive protein values were negatively correlated with mental developmental ind...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:10.1007/s13312-013-0091-3
更新日期:2013-03-01 00:00:00
abstract:OBJECTIVES:To evaluate efficacy of polymerase chain reaction (PCR), using the insertion sequence IS6110 as target for DNA, to detect Mycobacterium tuberculosis in body fluids of children with suspected tuberculosis (TB). SETTING:Hospitalized patients. METHODS:A comparison of PCR on body fluids, Acid Fast Bacilli stai...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:2000-04-01 00:00:00
abstract::Children with cow milk allergy are suspected to develop calcium metabolism disturbances. We observed increased markers of bone turnover in these children. Children with cow milk allergy are more prone to develop the disturbances of the bone mineralization even in the first year of life. ...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:10.1007/s13312-013-0194-x
更新日期:2013-07-01 00:00:00
abstract::Psychosocial assessment was carried out in 35 children with acute lymphatic leukemic, an equal number with non-leukemic chronic illness and their parents. Psychological dysfunction existed more frequently in parents of leukemic children. Depression as an initial reaction on being conveyed the diagnosis, was seen in 85...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:1992-08-01 00:00:00
abstract::Iodine deficiency disorders (IDD) is a public health problem in India. A ban on the sale of uniodised salt for household consumption has been introduced in Rajasthan State since 1992. The present study was conducted in the district of Bharatpur, Rajasthan with the objective to assess the prevalence of iodine disorders...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:2003-02-01 00:00:00
abstract::Thrombocytosis is a frequent finding in hemograms obtained from hospitalized and ambulatory children due to the widespread use of automated blood cell counters. Pediatricians are commonly puzzled in cases of thrombocytosis to determine the underlying cause and the need for therapy. The purpose of this review is to ass...
journal_title:Indian pediatrics
pub_type: 杂志文章,评审
doi:
更新日期:2008-08-01 00:00:00
abstract:OBJECTIVE:To compare the efficacy of artemether and quinine in the treatment of severe malaria in hospitalized children. STUDY DESIGN:Open randomized trial. SETTING:Pediatric ward of a tertiary care center. METHODS:All children admitted with clinical manifestations of severe malaria (as per WHO criteria) and asexual...
journal_title:Indian pediatrics
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:2003-10-01 00:00:00
abstract:BACKGROUND:Glycogen storage disease type VI (GSD-VI) presents with failure to thrive and also fibrosis in some cases, without cirrhosis. CASE CHARACTERISTICS:2½-year-old girl presented with short stature, transaminase elevation and significant fibrosis, suggesting GSD-III. OBSERVATION:A pathogenic mutation in PYGL ge...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:10.1007/s13312-017-1174-3
更新日期:2017-09-15 00:00:00
abstract::India established the National Tuberculosis Control Project (NTCP) 50 years ago and re-designed it as Revised NTCP (RNTCP) 19 years ago. Tuberculosis (TB) control was beset with obstacles-BCG vaccination was found ineffective in TB control in 1979; human immunodeficiency virus began spreading in India since 1984 with ...
journal_title:Indian pediatrics
pub_type: 历史文章,杂志文章
doi:10.1007/s13312-013-0021-4
更新日期:2013-01-08 00:00:00
abstract:OBJECTIVE:To estimate the prevalence of non-exclusive breastfeeding (NEBF) and quantify the out-of-pocket expenditure (OOPE) associated with NEBF and treatment of morbidity among infants up to six months of age. METHODS:Community based in an urban slum, among 172 mother-infant dyads selected by systematic random sampl...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:2020-12-15 00:00:00
abstract:OBJECTIVE:To compare the performance of respiratory rate and other clinical signs against pulse oximetry for predicting hypoxia in children with Severe pneumonia/Very severe disease as per Integrated Management of Neonatal and Childhood Illness (IMNCI) classification. DESIGN:Cross-sectional study. SETTING:Pediatric e...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:10.1007/s13312-017-1163-6
更新日期:2017-09-15 00:00:00
abstract::A 5 year old boy and a 10 year old girl presented with acute onset of psychotic disorder, which occurred one week after an upper respiratory infection. MRI images of brain were consistent with the diagnosis of acute disseminated encephalomyelitis (ADEM) in both cases. ADEM is one of the differential diagnoses to be co...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:2008-12-01 00:00:00
abstract:OBJECTIVE:To assess the utility of computer-aided facial analysis in identifying dysmorphic syndromes in Indian children. METHODS:Fifty-one patients with a definite molecular or cytogenetic diagnosis and recognizable facial dysmorphism were enrolled in the study and their facial photographs were uploaded in the Face2G...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:2019-12-15 00:00:00
abstract:OBJECTIVE:To study the relationship of CSF IL-1 beta and TNF-alpha with free radicals in acute bacterial meningitis (ABM) and to evaluate the clinical outcome in relation to the levels of these cytokines and free radicals in CSF. DESIGN:Prospective with controls. SETTING:Referral unit of a teaching hospital. METHODS...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:2000-06-01 00:00:00
abstract::Sixty children with acute bacterial meningitis (ABM) were prospectively studied for their serum sodium values and cerebrospinal fluid (CSF), serum and urinary osmolality. The results have been compared with 20 age and nutritionally matched controls. Even though mean serum osmolality (283.2 +/- 13.84 mOsm/kg) and serum...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:1993-10-01 00:00:00
abstract::There is a large child work force in India reported to be about 40 million. Child labor is being regarded as a form of modern slavery, as children are forced to work or have no choice to refuse work. Children are employed in a variety of occupations, many of which are hazardous. Exposure to machinery, pesticides, dust...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:2019-08-15 00:00:00
abstract:OBJECTIVE:To document effects of intrapartum risk factors for early onset sepsis (EOS) on CRP levels in neonates and to assess the suitability of this test in diagnosing EOS. DESIGN:Cohort study. SETTING:Labour and post natal wards in a tertiary level teaching hospital in India. SUBJECTS:250 neonates at risk of deve...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:2004-09-01 00:00:00
abstract::We studied the actual time taken to document temperature in a stable neonate by an electronic digital skin thermometer with automatic time beeper. We studied 100 neonates after initial stabilization. The mean time required for documenting the temperature by a electronic thermometer in axilla was 56.34+/-1.54 secs for ...
journal_title:Indian pediatrics
pub_type: 信件
doi:
更新日期:2009-12-01 00:00:00
abstract:OBJECTIVE:To evaluate the effect of canakinumab on growth parameters of patients with autoinflammatory diseases. METHODS:This retrospective study included Colchicine resistant familial Mediterranean fever (FMF), Mevalonate kinase deficiency (MKD), Tumor necrosis factor receptor-associated periodic fever syndrome (TRAP...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:2020-07-15 00:00:00
abstract:PURPOSE:Molecular basis of various forms of hyperinsulinemic hypoglycemia, involving defects in key genes regulating insulin secretion, are being increasingly reported. However, the management of medically unresponsive hyperinsulinism still remains a challenge as current facilities for genetic diagnosis and appropriate...
journal_title:Indian pediatrics
pub_type: 杂志文章,评审
doi:10.1007/s13312-015-0772-1
更新日期:2015-12-01 00:00:00
abstract::Hospital acquired enteric infections were investigated by studying 3138 children under 5 years of age who were admitted without diarrhea in nine medical words of a pediatric hospital, Calcutta during the period between March and September 1987. Three hundred and twenty (10.2%) children developed nosocomial diarrhea du...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:1993-02-01 00:00:00
abstract::We prospectively studied the effect of oral paracetamol in closing hemodynamically significant Patent ductus arteriosus in preterm infants (gestational age <32 weeks) where Ibuprofen was contraindicated. 29 of 40 neonates (72.5%) showed successful response while 11 (29.5%) failed to show any response. No major complic...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:2016-02-01 00:00:00
abstract::Seventy five mothers with lactation failure were studied, whose less than 4-month-old babies were admitted to the hospital. Partial lactational failure (94.7%) was noted more often than complete lactational failure (5.3%). Initiation of breastfeeding was delayed for 2 to 5 days usually for traditional reasons (77.3%) ...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:1992-12-01 00:00:00
abstract::The skinfold thickness (SFT) was measured in 750 Punjabi newborns at triceps and subscapular sites using a Harpenden's Caliper. It was correlated with various maternal and neonatal factors. SFT increased with increasing gestation but showed a decline after 40 weeks. There was a positive correlation of SFT with birth w...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:1991-11-01 00:00:00
abstract::A cross sectional study was conducted in 260 adolescent schoolchildren (114 males) in the age group of 11-18 years to estimate the prevalence of zinc deficiency in the National Capital Territory of Delhi. Serum zinc was estimated using Inductively coupled plasma mass spectrometer. Overall, 49.4% children (50.8% males,...
journal_title:Indian pediatrics
pub_type: 信件
doi:
更新日期:2011-12-01 00:00:00
abstract:OBJECTIVE:To determine the diagnostic accuracy of Indian Scale for Assessment of Autism (ISAA) in children aged between 2-5 years. Design: Setting:. STUDY DESIGN:Study of diagnostic accuracy. PARTICIPANTS:A consecutive sample of 500 children with suspected Autism (delay or regression of developmental milestones, dela...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:2019-10-15 00:00:00
abstract::No clear operational definition of 'Community Participation' has emerged over the last decade of experimentation. One reason is the markedly contrasting perspectives that exist at different levels such as Aid Agencies, Ministry of Health, Government Health Programmes and Non-Government Organizations (NGOs). A more pra...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:1989-11-01 00:00:00
abstract:OBJECTIVES:To identify important factors (linked to lifestyle, eating and sedentary behaviors) relating to waist circumference among urban South Indian children aged 3 to 16 years. DESIGN:Cross sectional. SETTING:Urban schools of Bangalore, from August 2008 to January 2010. PARTICIPANTS:8444 children; 4707 children ...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:10.1007/s13312-012-0027-3
更新日期:2012-02-01 00:00:00
abstract:OBJECTIVE:To assess the safety and reactogenecity of indigenously produced measles vaccine derived from EZ strain. DESIGN:A longitudinal clinical follow up after vaccination. SETTING:Hospital based and home follow up, as required. SUBJECTS:12,470 children, 9 to 15 months old, immunized with measles vaccine of EZ str...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:1996-10-01 00:00:00
abstract:CONTEXT:Cryptosporidium spp. is a zoonotic infection, now being recognized as a significant cause of diarrhea in both immunocompetent and immunocompromised hosts. However, there still exist significant knowledge gaps in its estimated global burden, epidemiology, diagnosis and management. EVIDENCE ACQUISITION:A semi-sy...
journal_title:Indian pediatrics
pub_type: 杂志文章,评审
doi:10.1007/s13312-017-1093-3
更新日期:2017-04-15 00:00:00