Changes in immune-endocrine response after surgery.

abstract：:Lung cancer is a common malignant disease, nearly 2.09 million new patients occurred last year. Approximately 85% of the patients are classified as non-small-cell lung cancer (NSCLC). It is therefore important to identify new diagnostic and prognostic biomarkers for the early detection of this disease. The presented s...

journal_title：Cytokine

authors： Cai D,Xu Y,Ding R,Qiu K,Zhang R,Wang H,Huang L,Xie X,Yan H,Deng Y,Lin X,Shao J,Luo X,Duan C

更新日期：2020-02-01 00:00:00

abstract：:This moleculo-epidemiological and immunological study through cytokine response assessment was done to know the dynamics of cytokines in the initiation, persistence and association to physiological changes of a particular pathogen in water buffaloes. This is important to understand the magnitude and behavior of diseas...

journal_title：Cytokine

authors： Mingala CN,Konnai S,Cruz LC,Onuma M,Ohashi K

更新日期：2009-05-01 00:00:00

abstract：:In this study we investigated mechanisms involved in the chronic character of experimental collagen type II induced arthritis (CIA). We compared the knee joints of mouse strains which are prone to develop this autoimmune disease (DBA/1,B10RIII) with other nonsusceptible mouse strains (C57Bl/6,BALB/c) in their reaction...

journal_title：Cytokine

authors： Blom AB,van Lent PL,Holthuysen AE,van den Berg WB

更新日期：1999-12-01 00:00:00

abstract：:Tumour necrosis factor (TNF) is a key regulator of inflammation and immunity. The cellular effects exerted by TNF depend, apart from NF-kappaB-directed gene transcription, largely on its ability to activate phospholipase A2(PLA2), yielding the release of arachidonic acid (AA) and its metabolites. AA metabolites, espec...

journal_title：Cytokine

authors： van Puijenbroek AA,Wissink S,van der Saag PT,Peppelenbosch MP

更新日期：1999-02-01 00:00:00

abstract：:Colony stimulating factors (CSF) promote leukocyte survival by reducing apoptotic cell death. However, their effects on non-leukocyte cell types are unclear. Reduced apoptosis in colon epithelial cells is thought to contribute to the initiation of cancer. Here, we report diminished spontaneous apoptosis of human colon...

journal_title：Cytokine

authors： Calatayud S,Warner TD,Breese EJ,Mitchell JA

更新日期：2002-11-24 00:00:00

abstract：:Macrophage migration inhibitory factor (MIF) is a molecule with plethora of functions such as regulation of immune response, hormone-like, enzymatic and chaperone-like activity. Further, MIF is a major participant in glucose homeostasis since it is an autocrine stimulator of insulin secretion. MIF absence in male knoc...

journal_title：Cytokine

authors： Vujicic M,Senerovic L,Nikolic I,Saksida T,Stosic-Grujicic S,Stojanovic I

更新日期：2014-09-01 00:00:00

abstract：:IL-18 is a pleiotropic and multifunctional cytokine that belongs to the IL-1 family. It is produced as a biologically inactive precursor, which is cleaved into its active mature form mainly by caspase-1. The caspase becomes active from its inactive precursor (procaspase-1) upon assembly of an inflammasome. Because of ...

journal_title：Cytokine

authors： Samarani S,Allam O,Sagala P,Aldabah Z,Jenabian MA,Mehraj V,Tremblay C,Routy JP,Amre D,Ahmad A

更新日期：2016-06-01 00:00:00

abstract：:Surgery is followed by an acute-phase response, including hypothalamo-pituitary-adrenal (HPA)-axis activation and fever. Considering its physiological properties and its behaviour in plasma after stress and surgery, the pro-inflammatory cytokine interleukin (IL)-6 is a putative candidate in eliciting these stress-rela...

journal_title：Cytokine

authors： De Jongh RF,Vissers KC,Booij LH,De Jongh KL,Vincken P,Meert TF

更新日期：2003-03-07 00:00:00

abstract：:We have cloned and performed the first functional characterization of the chemokine receptor, CCR3, of Cynomolgus monkey (Macaca fascicularis). The deduced amino acid sequence of the cloned Cynomolgus CCR3 was found to be more similar to that of a previously-reported Rhesus (Macaca mulatta) CCR3 (99.4%) than that of a...

journal_title：Cytokine

authors： Iino T,Sugimoto H,Watanabe A,Encinas JA,Liu N,Floeckner J,Bacon KB

更新日期：2002-09-21 00:00:00

abstract：:The purpose of these studies was to test whether pentoxifylline, a drug that can inhibit the production and action of cytokines hypothesized to be endogenous pyrogens (for example, interleukin 1 and tumor necrosis factor [TNF]), is antipyretic. We also tested the effects of pentoxifylline on plasma activities of inter...

journal_title：Cytokine

authors： LeMay LG,Vander AJ,Kluger MJ

更新日期：1990-07-01 00:00:00

abstract：OBJECTIVES:To investigate the distribution of multiple cytokines in gastroschisis and reveal its association with clinical outcomes, including gastrointestinal disorders and fetal brain damage caused by chronic inflammation in gastroschisis. METHODS:We obtained amniotic fluid and arterial cord blood from 10 patients w...

journal_title：Cytokine

authors： Owaki T,Imai K,Miki R,Niwa Y,Kotani T,Nakano-Kobayashi T,Ushida T,Kajiyama H

更新日期：2021-02-01 00:00:00

abstract：OBJECTIVES:Vascular endothelial cell growth factor (VEGF) plays an important role in the biology of gynecological cancer, usually linked with aggressive tumour behaviour and a poor postoperative outcome. Yet, its role in benign breast/gynecological conditions is less clear. METHODS:Serum VEGF was analysed in a series ...

journal_title：Cytokine

authors： Koukourakis MI,Limberis V,Tentes I,Kontomanolis E,Kortsaris A,Sivridis E,Giatromanolaki A

更新日期：2011-03-01 00:00:00

abstract：:In hypertension studies, anti-inflammatory cytokine interleukin-10 (IL-10) has been shown to prevent angiotensin II (Ang II)-induced vasoconstriction and regulate vascular function by down-regulating pro-inflammatory cytokine and superoxide production in vascular cells. However, little is known about the mechanism beh...

journal_title：Cytokine

authors： Kim HY,Kim HS

更新日期：2016-01-01 00:00:00

abstract：:Given the known anti-tumorigenic properties of IFNγ, its effect on glioma cell survival was investigated. Though IFNγ had no effect on glioma cell viability, it induced cell cycle arrest. This was accompanied by increased expression of p53 and retinoic acid inducible gene (RIG-I). While RIG-I had no effect on glioma c...

journal_title：Cytokine

authors： Ghildiyal R,Sen E

更新日期：2017-01-01 00:00:00

abstract：:Studies have shown that following bacterial infection or endotoxin administration, immune functions are regulated differently in mice of different genetic background. Since the susceptibility to sepsis following trauma-hemorrhage is dependant on the severity of injury, it is important to determine whether genetic back...

journal_title：Cytokine

authors： Matsutani T,Anantha Samy TS,Kang SC,Bland KI,Chaudry IH

更新日期：2005-05-21 00:00:00

abstract：:Burn injury is associated with profound inflammation and activation of the innate immune system involving gammadelta T-cells. Similarly, Toll-like receptors (TLR) are associated with activation of the innate immune response; however, it is unclear whether TLR expression is altered in gammadelta T-cells after major bur...

journal_title：Cytokine

authors： Schwacha MG,Daniel T

更新日期：2008-12-01 00:00:00

abstract：:Recent studies have implicated leptin as a "stress" hormone and highlighted its association with increases in inflammatory cytokines, C-reactive protein and cortisol. In order to investigate the exact temporal leptin response to stress we undertook a detailed longitudinal study of circulating leptin concentrations dur...

journal_title：Cytokine

authors： Wallace AM,Sattar N,Mcmillan DC

更新日期：2000-07-01 00:00:00

abstract：:Increased cerebrospinal fluid (CSF) IL-6 has been reported in patients with Behçet's disease (BD) and neurological involvement. To elucidate the value of IL-6 as a marker of disease activity, serum and CSF IL-6 levels of 68 BD patients with acute (26) or chronic progressive (14) parenchymal involvement (pNB), dural si...

journal_title：Cytokine

authors： Akman-Demir G,Tüzün E,Içöz S,Yeşilot N,Yentür SP,Kürtüncü M,Mutlu M,Saruhan-Direskeneli G

更新日期：2008-12-01 00:00:00

abstract：:Murine fibrosarcoma L929 cells were transfected with human Fas cDNA. The mode of cell death was analysed following treatment either with tumour necrosis factor (TNF) or with agonistic antibodies to Fas. While triggering of the TNF receptors led to necrosis, clustering of the Fas antigen resulted in apoptotic cell deat...

journal_title：Cytokine

authors： Vercammen D,Vandenabeele P,Beyaert R,Declercq W,Fiers W

更新日期：1997-11-01 00:00:00

abstract：OBJECTIVE:Current orthopedic therapies, aimed solely at symptomatic control, are unable to restore the cytokine imbalance that produces the hallmark clinical profile of osteoarthritis. While a myriad of chemical factors in the cytokine network stimulate local joint inflammation and pain, Interleukin 1 (IL-1) is widely ...

journal_title：Cytokine

authors： Barreto A,Braun TR

更新日期：2016-05-01 00:00:00

abstract：:Clara cell protein (CC16) is an endogenous anti-inflammatory agent. It is produced mainly in the respiratory and urogenital tracts. CC16 has been quantified in serum, but not in cerebrospinal fluid (CSF). The aim of this study was to examine CSF CC16 in relation to age, gender and serum CC16, and to examine CC16 level...

journal_title：Cytokine

authors： De Jongh R,Vranken J,Kenis G,Bosmans E,Maes M,Stans G,De Ley M,Heylen R

更新日期：1998-06-01 00:00:00

abstract：:Visfatin is an important adipokines, which are expressed in different tissues including ovary of mammals. The postnatal ovary in rodents undergoes dramatic changes of intra-ovarian factors in relation to proliferation and apoptosis. There are studies which showed that gonadal visfatin changes in postnatal life. Howeve...

journal_title：Cytokine

authors： Annie L,Gurusubramanian G,Kumar Roy V

更新日期：2021-01-18 00:00:00

abstract：UNLABELLED:Burn is associated with profound inflammation and activation of the innate immune system in multiple organ beds, including the lung. Similarly, toll-like receptors (TLR) are associated with innate immune activation. Nonetheless, it is unclear what impact burn has on TLR-induced inflammatory responses in the ...

journal_title：Cytokine

authors： Oppeltz RF,Rani M,Zhang Q,Schwacha MG

更新日期：2011-09-01 00:00:00

abstract：:The protective effect of interleukin 1 alpha (IL-1 alpha) in mice with acetaminophen (AAP)-induced hepatitis was investigated. IL-1 alpha had a significant protective effect if given 2 or more hours (up to 24 hours) before AAP; it significantly reduced mortality of mice and decreased serum transaminase level. The maxi...

journal_title：Cytokine

authors： Renić M,Culo F,Bilić A,Bukovec Z,Sabolović D,Zupanović Z

更新日期：1993-05-01 00:00:00

abstract：:iNKT cells, CD1d dependent natural killer T cells are a unique population of T cells. The capacity of iNKT cells to produce regulatory cytokines first provided an indication of their regulatory potential. Later on, in experimental models as well as in patients afflicted with an auto-immune disease, such as Type 1 diab...

journal_title：Cytokine

authors： Novak J,Lehuen A

更新日期：2011-03-01 00:00:00

abstract：:Expression of GPCR fatty acid sensor/receptor genes in adipocytes is modulated by inflammatory mediators, particularly IL-1β. In this study we examined whether the IL-1 gene superfamily member, IL-33, also regulates expression of the fatty acid receptor genes in adipocytes. Human fat cells, differentiated from preadip...

journal_title：Cytokine

authors： Zaibi MS,Kępczyńska MA,Harikumar P,Alomar SY,Trayhurn P

更新日期：2018-10-01 00:00:00

abstract：AIMS:This study investigates the relationships between matrix metalloproteinases, inflammations mediators and type 2 diabetes mellitus in Tunisians metabolic syndrome (Mets) patients. METHODS:The study has included 239 MetS patients and 247 controls. Mets was defined according to the NCEP-ATPIII report. Mets patients ...

journal_title：Cytokine

authors： Zayani Y,El Golli N,Zidi W,Guizani I,Boussairi S,Aloui S,Ayadi I,Ftouhi B,Feki M,Ben Romdhane N,Ben Sliman H,Allal-Elasmi M,Kaabachi N

更新日期：2016-10-01 00:00:00

abstract：:The production of nitric oxide (NO) is increased in experimental nephritis, with NO thought to be an important mediator of cell damage. The cytokines interleukin 1 beta (IL-1 beta), IL-6, IL-8, monocyte chemotactic protein-1 (MCP-1) and transforming growth factor-beta (TGF-beta) are released from mesangial cells in vi...

journal_title：Cytokine

authors： Ikeda M,Ikeda U,Ohkawa F,Shimada K,Kano S

更新日期：1994-11-01 00:00:00

abstract：BACKGROUND:Unregulated inflammatory and thrombotic responses have been proposed to be important causes of early brain injury and worse clinical outcomes after subarachnoid hemorrhage (SAH). OBJECTIVE:We hypothesize that SAH is characterized by an increased inflammatory and thrombotic state and disruption of associatio...

journal_title：Cytokine

authors： Savarraj JP,McGuire MF,Parsha K,Hergenroeder G,Bajgur S,Ahn S,Zhu L,Espino E,Chang T,Blackburn S,Kim DH,Dash P,Choi HA

更新日期：2018-11-01 00:00:00

abstract：:Despite vaccine efforts, influenza outbreaks pose a significant threat to global public health. There are two commercially available seasonal influenza vaccines in the United States: the trivalent inactivated vaccine (TIV), delivered parenterally, and the live attenuated influenza vaccine (LAIV), delivered intranasall...

journal_title：Cytokine

authors： Ramakrishnan A,Althoff KN,Lopez JA,Coles CL,Bream JH

更新日期：2012-12-01 00:00:00