Antigenic profiles of endothelial and hemopoietic lineages in murine intraembryonic hemogenic sites.

Abstract:

:Two hemogenic sites are present in mouse embryos before the onset of fetal liver hemopoiesis. While the yolk sac provides for immediate erythropoiesis, an intraembryonic region encompassing the dorsal aorta produces definitive hematopoietic stem cells, as shown experimentally. At early developmental stages this region, that we named paraaortic splanchnopleura, produces multipotent progenitors. At the time of fetal liver colonisation, the paraaortic splanchnopleura further evolves into aorta, gonads and mesonephros (AGM) and contains progenitors capable of long term multilineage reconstitution. Only then are cytologically identifiable collections of early hemopoietic cells present in various arteries and in the mesentery. The present report focuses on the antigenic characterisation of immature hemopoietic progenitors in order to trace back the intraembryonic precursors at earlier developmental stages. CD34, an antigen expressed by immature progenitors and endothelial cells, labels all potential hemopoietic sites. Markers, supposed to counterstain endothelial cells and spare CD34+ hemopoietic cells, also stain various hemopoietic cells. The meaning of these shared antigenic expressions between cells of the endothelial and hemopoietic lineages in the early embryo is discussed.

journal_name

Dev Comp Immunol

authors

Garcia-Porrero JA,Manaia A,Jimeno J,Lasky LL,Dieterlen-Lièvre F,Godin IE

doi

10.1016/s0145-305x(98)00006-8

subject

Has Abstract

pub_date

1998-05-01 00:00:00

pages

303-19

issue

3

eissn

0145-305X

issn

1879-0089

pii

S0145-305X(98)00006-8

journal_volume

22

pub_type

杂志文章
  • Alterations in the activities of tyrosinase, N-acetyltransferase, and tyrosine aminotransferase in immune reactive larvae of Drosophila melanogaster.

    abstract::The activities of three enzymes, tyrosinase (monophenol oxidase, MPO), N-acetyltransferase (NAT), and tyrosine aminotransferase (TAT), were studied during eumelanotic encapsulation in host larvae of Drosophila melanogaster parasitized by the wasp, Leptopilina boulardi. At 24 h postinfection there was a tenfold increas...

    journal_title:Developmental and comparative immunology

    pub_type: 杂志文章

    doi:10.1016/0145-305x(93)90021-h

    authors: Vass E,Nappi AJ,Carton Y

    更新日期:1993-03-01 00:00:00

  • Molecular cloning, genomic organization and functional analysis of an anti-lipopolysaccharide factor from Chinese mitten crab Eriocheir sinensis.

    abstract::Anti-lipopolysaccharide factor (ALF) represents one kind of basic proteins, which binds and neutralizes LPS and exhibits strong antibacterial activity against Gram-negative R-type bacteria. The ALF gene of Chinese mitten crab Eriocheir sinensis (Milne Edwards, 1853) (denoted as EsALF) was identified from haemocytes by...

    journal_title:Developmental and comparative immunology

    pub_type: 杂志文章

    doi:10.1016/j.dci.2007.11.008

    authors: Li C,Zhao J,Song L,Mu C,Zhang H,Gai Y,Qiu L,Yu Y,Ni D,Xing K

    更新日期:2008-01-01 00:00:00

  • The diversity of C-type lectins in the genome of a basal metazoan, Nematostella vectensis.

    abstract::C-type lectins (CTLs) are involved in cell-cell adhesion, recognition, and innate immunity in higher vertebrates, but little is known about CTLs in basal metazoans. The recent sequencing of the cnidarian Nematostella vectensis genome allowed us to explore the CTL-like gene family at the base of metazoan evolution. Six...

    journal_title:Developmental and comparative immunology

    pub_type: 杂志文章

    doi:10.1016/j.dci.2009.01.008

    authors: Wood-Charlson EM,Weis VM

    更新日期:2009-08-01 00:00:00

  • Localization and bacteriostasis of Vibrio introduced into the Pacific white shrimp, Litopenaeus vannamei.

    abstract::Although numerous mechanisms of immune defense have been described in crustaceans, the tissue distribution and fate of live bacteria introduced into the host remain unclear. In the present study, Litopenaeus vannamei were injected with a sub-lethal dose of kanamycin-resistant Vibrio campbellii expressing green fluores...

    journal_title:Developmental and comparative immunology

    pub_type: 杂志文章

    doi:10.1016/j.dci.2005.01.004

    authors: Burgents JE,Burnett LE,Stabb EV,Burnett KG

    更新日期:2005-01-01 00:00:00

  • Functional studies on Calliphora vomitoria haemocyte subpopulations defined by lectin staining and density centrifugation.

    abstract::Haemocyte subpopulations of Calliphora vomitoria have been categorized by their surface staining properties using fluorescently labelled lectins, and their mobilities in Percoll density gradients. These methods of identification were exploited to determine the roles of these cell types in cellular defence reactions. S...

    journal_title:Developmental and comparative immunology

    pub_type: 杂志文章

    doi:10.1016/0145-305x(92)90048-h

    authors: McKenzie AN,Preston TM

    更新日期:1992-01-01 00:00:00

  • Proteomic analysis of host responses to Marek's disease virus infection in spleens of genetically resistant and susceptible chickens.

    abstract::Resistance to Marek's disease (MD) in chickens is genetically regulated and there are lines of chickens with differential susceptibility or resistance to this disease. The present study was designed to study comparative changes in the spleen proteomes of MD-susceptible B19 and MD-resistant B21 chickens in response to ...

    journal_title:Developmental and comparative immunology

    pub_type: 杂志文章

    doi:10.1016/j.dci.2010.01.016

    authors: Thanthrige-Don N,Parvizi P,Sarson AJ,Shack LA,Burgess SC,Sharif S

    更新日期:2010-07-01 00:00:00

  • Bax functions as coelomocyte apoptosis regulator in the sea cucumber Apostichopus japonicus.

    abstract::Bcl-2-associated X (Bax) belongs to the Bcl-2 protein family and its pro-apoptotic function has been confirmed in many vertebrate species. However, the functional role of Bax in apoptosis in invertebrates is limited. Here, a Bax homologue (AjBax) in Apostichopus japonicas was cloned and characterized, and its pro-apop...

    journal_title:Developmental and comparative immunology

    pub_type: 杂志文章

    doi:10.1016/j.dci.2019.103490

    authors: Guo M,Lv M,Shao Y,Zhang W,Zhao X,Li C

    更新日期:2020-01-01 00:00:00

  • Characterization of immunoreactive TNF alpha molecules in the gastropod Biomphalaria glabrata.

    abstract::In recent years, several studies have demonstrated the existence of cytokine-like molecules in invertebrates, therefore suggesting that cytokines may have been conserved throughout evolution. In this study, we investigated the presence of immunoreactive TNF alpha (ir TNF alpha) in the gastropod mollusc Biomphalaria gl...

    journal_title:Developmental and comparative immunology

    pub_type: 杂志文章

    doi:10.1016/0145-305x(94)90013-2

    authors: Ouwe-Missi-Oukem-Boyer O,Porchet E,Capron A,Dissous C

    更新日期:1994-05-01 00:00:00

  • Expression and function of triggering receptor expressed on myeloid cells-1 (TREM-1) on canine neutrophils.

    abstract::The dog is both a valued veterinary species and a widely used translational model for sepsis research. However, relatively little work has been performed evaluating potential biomarkers present during canine infection. Triggering receptor expressed on myeloid cells-1 (TREM-1) has shown promise as a biomarker for infec...

    journal_title:Developmental and comparative immunology

    pub_type: 杂志文章

    doi:10.1016/j.dci.2011.03.021

    authors: Li J,Birkenheuer AJ,Marr HS,Levy MG,Yoder JA,Nordone SK

    更新日期:2011-08-01 00:00:00

  • Immulectin-2, a pattern recognition receptor that stimulates hemocyte encapsulation and melanization in the tobacco hornworm, Manduca sexta.

    abstract::In insects, encapsulation followed by melanization is a major defense mechanism against metazoan parasites. However, insects must recognize and differentiate nonself before they mount an immune response. Recognition of pathogens in insects is accomplished by a set of pattern recognition receptors (PRRs). Binding of PR...

    journal_title:Developmental and comparative immunology

    pub_type: 杂志文章

    doi:10.1016/j.dci.2004.02.005

    authors: Yu XQ,Kanost MR

    更新日期:2004-07-01 00:00:00

  • Functional characterization of duck LSm14A in IFN-β induction.

    abstract::Human LSm14A is a key component of processing body (P-body) assembly that mediates interferon-β (IFN-β) production by sensing viral RNA or DNA. To the best of our knowledge, we are the first to report duck LSm14A (duLSm14A) cloning from duck embryo fibroblasts (DEFs). Full-length duLSm14A encoded 461 amino acids and w...

    journal_title:Developmental and comparative immunology

    pub_type: 杂志文章

    doi:10.1016/j.dci.2017.06.014

    authors: Hua K,Li H,Chen H,Foda MF,Luo R,Jin H

    更新日期:2017-11-01 00:00:00

  • Immunological regulation by a β-adrenergic-like octopamine receptor gene in crowded larvae of the oriental Armyworm, Mythmina separata.

    abstract::Recent reports demonstrate that octopamine plays an important immunological role in crowded larvae of the Oriental Armyworm, Mythmina separata. We identified an octopamine receptor, the β-adrenergic-like gene (designated MsOctβ2R), with a 1191 bp open reading frame that encodes 396 amino acids and contains seven conse...

    journal_title:Developmental and comparative immunology

    pub_type: 杂志文章

    doi:10.1016/j.dci.2020.103802

    authors: Kong H,Yuan L,Dong C,Zheng M,Jing W,Tian Z,Hou Q,Cheng Y,Zhang L,Jiang X,Luo L

    更新日期:2020-12-01 00:00:00

  • The roles of antimicrobial peptide, rip-thanatin, in the midgut of Riptortus pedestris.

    abstract::Recently, we have reported the structural determination of antimicrobial peptides (AMPs), such as riptocin, rip-defensin, and rip-thanatin, from Riptortus pedestris. However, the biological roles of AMPs in the host midgut remain elusive. Here, we compared the expression levels of AMP genes in apo-symbiotic insects wi...

    journal_title:Developmental and comparative immunology

    pub_type: 杂志文章

    doi:10.1016/j.dci.2017.09.009

    authors: Park KE,Jang SH,Lee J,Lee SA,Kikuchi Y,Seo YS,Lee BL

    更新日期:2018-01-01 00:00:00

  • The oyster immunity.

    abstract::Oysters, the common name for a number of different bivalve molluscs, are the worldwide aquaculture species and also play vital roles in the function of ecosystem. As invertebrate, oysters have evolved an integrated, highly complex innate immune system to recognize and eliminate various invaders via an array of orchest...

    journal_title:Developmental and comparative immunology

    pub_type: 杂志文章,评审

    doi:10.1016/j.dci.2017.05.025

    authors: Wang L,Song X,Song L

    更新日期:2018-03-01 00:00:00

  • Antimicrobial mechanisms of fish leukocytes.

    abstract::Early activation and coordination of innate defenses are critical for effective responses against infiltrating pathogens. Rapid engagement of immune cells provides a critical first line of defense soon after pathogen infiltration. Activation leads to a well-orchestrated set of events that sees the induction and regula...

    journal_title:Developmental and comparative immunology

    pub_type: 杂志文章,评审

    doi:10.1016/j.dci.2011.03.009

    authors: Rieger AM,Barreda DR

    更新日期:2011-12-01 00:00:00

  • DNA content and proliferation of rat thymocytes.

    abstract::Scanning microdensitometric analysis of Feulgen stained thymocytes from rats aged 1 to 71 days revealed the presence of a number of waves of cell proliferation which may correlate with the development of functionally distinct T-cell subpopulations. In addition, considerable numbers of hypodiploid cells were seen. It i...

    journal_title:Developmental and comparative immunology

    pub_type: 杂志文章

    doi:10.1016/0145-305x(84)90021-1

    authors: Rippin JW

    更新日期:1984-01-01 00:00:00

  • A Kazal-type serine proteinase inhibitor SPIPm2 from the black tiger shrimp Penaeus monodon is involved in antiviral responses.

    abstract::A five-domain Kazal-type serine proteinase inhibitor, SPIPm2, from Penaeus monodon has recently been implicated in antiviral responses for it is up-regulated upon viral infection and needs further studies. The SPIPm2 genomic gene was composed of seven exons and six introns. The genomic DNA segments coding for each Kaz...

    journal_title:Developmental and comparative immunology

    pub_type: 杂志文章

    doi:10.1016/j.dci.2010.06.001

    authors: Donpudsa S,Ponprateep S,Prapavorarat A,Visetnan S,Tassanakajon A,Rimphanitchayakit V

    更新日期:2010-10-01 00:00:00

  • Damselfish with neurofibromatosis exhibit cytotoxicity toward tumor targets.

    abstract::Damselfish neurofibromatosis (DNF) is a malignant transmissible disease affecting Schwann cells, and is the only naturally occurring animal model of human neurofibromatosis type 1. The current study was designed to determine whether fish in the early stages of disease have measurable immune responses toward DNF tumor ...

    journal_title:Developmental and comparative immunology

    pub_type: 杂志文章

    doi:10.1016/s0145-305x(94)90356-5

    authors: McKinney EC,Schmale MC

    更新日期:1994-07-01 00:00:00

  • Correlated expression profile of extracellular matrix-related molecules during the inflammatory response of the teleost fish gilthead seabream.

    abstract::Extracellular matrix (ECM) components, in addition to their structural functions, interact with cell surface receptors and intracellular components to modulate the transduction of signals for cell growth, differentiation, migration, proliferation, polarization, apoptosis and inflammation. Our previous findings in the ...

    journal_title:Developmental and comparative immunology

    pub_type: 杂志文章

    doi:10.1016/j.dci.2010.05.007

    authors: Castillo-Briceño P,Arizcun-Arizcun M,Meseguer J,Mulero V,García-Ayala A

    更新日期:2010-10-01 00:00:00

  • A novel IgA-like immunoglobulin in the reptile Eublepharis macularius.

    abstract::The appearance of antibody genes over evolution coincided with the origin of the vertebrates. Reptiles are of great interest in evolution since they are the link between the amphibians, birds, and mammals. This work describes the presence of a gene in the reptile leopard gecko (Eublepharis macularius) where phylogenet...

    journal_title:Developmental and comparative immunology

    pub_type: 杂志文章

    doi:10.1016/j.dci.2006.09.005

    authors: Deza FG,Espinel CS,Beneitez JV

    更新日期:2007-01-01 00:00:00

  • Lipopolysaccharide activates the sea urchin immune system.

    abstract::Profilin is a small, actin-binding protein that functions at the intersection of signal transduction and cytoskeletal modifications. Increases in the number of profilin messages per cell correlate with sea urchin coelomocytes activation in response to injury. Here we show that coelomocytes respond to immune challenge ...

    journal_title:Developmental and comparative immunology

    pub_type: 杂志文章

    doi:10.1016/0145-305x(95)00009-i

    authors: Smith LC,Britten RJ,Davidson EH

    更新日期:1995-05-01 00:00:00

  • The immune system of sea bass, Dicentrarchus labrax, reared in aquaculture.

    abstract::The sea bass Dicentrarchus labrax is one the most important seawater fish species of south Europe and Mediterranean aquaculture, and studies on its immune system are important for both scientific and applied purposes. In this paper, we summarise the results obtained in studies of the immune system in this species, and...

    journal_title:Developmental and comparative immunology

    pub_type: 杂志文章,评审

    doi:10.1016/s0145-305x(01)00057-x

    authors: Scapigliati G,Romano N,Buonocore F,Picchietti S,Baldassini MR,Prugnoli D,Galice A,Meloni S,Secombes CJ,Mazzini M,Abelli L

    更新日期:2002-03-01 00:00:00

  • Identification and comparative analysis of three novel C-type lectins from the silkworm with functional implications in pathogen recognition.

    abstract::C-type lectins can act as pattern recognition receptors (PRRs) in innate immunity. Previously, we identified two C-type lectins from silkworm (Bombyx mori), BmLBP and BmMBP, as PRRs. In the present study, we identified three homologs of these lectins by searching the silkworm genome database. These novel B. mori low-e...

    journal_title:Developmental and comparative immunology

    pub_type: 杂志文章

    doi:10.1016/j.dci.2009.01.005

    authors: Takase H,Watanabe A,Yoshizawa Y,Kitami M,Sato R

    更新日期:2009-06-01 00:00:00

  • Two mannose-binding lectin homologues and an MBL-associated serine protease are expressed in the gut epithelia of the urochordate species Ciona intestinalis.

    abstract::The lectin complement pathway has important functions in vertebrate host defence and accumulating evidence of primordial complement components trace its emergence to invertebrate phyla. We introduce two putative mannose-binding lectin homologues (CioMBLs) from the urochordate species Ciona intestinalis. The CioMBLs di...

    journal_title:Developmental and comparative immunology

    pub_type: 杂志文章

    doi:10.1016/j.dci.2009.08.004

    authors: Skjoedt MO,Palarasah Y,Rasmussen K,Vitved L,Salomonsen J,Kliem A,Hansen S,Koch C,Skjodt K

    更新日期:2010-01-01 00:00:00

  • Molecular cloning and characterisation of chicken IL-18 binding protein.

    abstract::The human IL-1 receptor family is comprised of 11 membrane bound or soluble receptors and the IL-18 binding protein (IL-18BP). These receptors are dispersed across seven genomic loci, with the majority at a single locus. Direct orthologues were identified in the chicken at conserved genomic loci; however, the IL-18BP ...

    journal_title:Developmental and comparative immunology

    pub_type: 杂志文章

    doi:10.1016/j.dci.2020.103850

    authors: Gibson MS,Steyn A,Kealy D,Kaspers B,Fife MS

    更新日期:2021-01-01 00:00:00

  • Purification and properties of agglutinins from conger eel, Conger Myriaster (Brevoort), skin mucus.

    abstract::The skin mucus of the conger eel, Conger myriaster, contains galactose-specific agglutinins. Hemagglutinating activity is independent of divalent cations and is destroyed by heating at 50 degrees C for 15 min. The mucus agglutinins, named congerins, are a mixture of proteins with different electrical charges. Three of...

    journal_title:Developmental and comparative immunology

    pub_type: 杂志文章

    doi:10.1016/0145-305x(88)90007-9

    authors: Kamiya H,Muramoto K,Goto R

    更新日期:1988-04-01 00:00:00

  • Functional characterization of STATa/b genes encoding transcription factors from Branchiostoma belcheri.

    abstract::The signal transducer and activator of transcription (STAT), as an important transcription factor of the Janus kinase (JAK)-STAT signaling pathway, is pivotal for development and immunity and well documented in vertebrates. However, the STAT gene has not been reported in chordate amphioxus (Branchiostoma belcheri). In...

    journal_title:Developmental and comparative immunology

    pub_type: 杂志文章

    doi:10.1016/j.dci.2020.103838

    authors: Cao Y,Fang T,Fan M,Wang L,Lv C,Xiaojun Song,Jin P,Ma F

    更新日期:2021-01-01 00:00:00

  • A different repertoire of Galleria mellonella antimicrobial peptides in larvae challenged with bacteria and fungi.

    abstract::To date, functioning of insect humoral immune response is especially well described in Diptera. The mechanisms of pathogen recognition, activation of signaling pathways and regulation of antimicrobial defense peptide expression are relatively well known. The present paper demonstrates evidence that the immune system o...

    journal_title:Developmental and comparative immunology

    pub_type: 杂志文章

    doi:10.1016/j.dci.2010.06.005

    authors: Mak P,Zdybicka-Barabas A,Cytryńska M

    更新日期:2010-10-01 00:00:00

  • Vaccination with UV-inactivated nodavirus partly protects European sea bass against infection, while inducing few changes in immunity.

    abstract::Developing viral vaccines through the ultraviolet (UV) inactivation of virus is promising technique since it is straightforward and economically affordable, while the resulting viruses are capable of eliciting an adequate antiviral immune response. Nodavirus (NNV) is a devastating virus that mainly affects European se...

    journal_title:Developmental and comparative immunology

    pub_type: 杂志文章

    doi:10.1016/j.dci.2018.05.013

    authors: Valero Y,Mokrani D,Chaves-Pozo E,Arizcun M,Oumouna M,Meseguer J,Esteban MÁ,Cuesta A

    更新日期:2018-09-01 00:00:00

  • Cloning and sequencing of caspase 6 in rainbow trout, Oncorhynchus mykiss, and analysis of its expression under conditions known to induce apoptosis.

    abstract::The rainbow trout caspase 6 gene has been cloned and sequenced. The open reading frame consisted of 906bp, which translated into a protein of 302 amino acids, containing the caspase active site pentapeptide (QACRG) and the caspase family signature (HADADCFVCVFLSHG). Amino acids involved in catalysis and those known to...

    journal_title:Developmental and comparative immunology

    pub_type: 杂志文章

    doi:10.1016/s0145-305x(00)00061-6

    authors: Laing KJ,Holland J,Bonilla S,Cunningham C,Secombes CJ

    更新日期:2001-05-01 00:00:00