Histologic assessment of mineral trioxide aggregate as a root-end filling in monkeys.

Abstract:

:Mineral Trioxide Aggregate (MTA) has been shown in a number of experiments to be a potential root-end filling material. The purpose of this study was to examine the periradicular tissue response of monkeys to MTA and amalgam as root-end fillings. The pulps were removed from all the maxillary incisors of three monkeys. The root canals were prepared and filled with laterally condensed guttapercha and sealer, and the access cavities were restored with amalgam. Buccal mucoperiosteal flaps were raised, and root-end resections were performed before root-end cavity preparation with burs. The root-end cavities in half of the teeth were filled with MTA, while amalgam was placed in the other cavities. After 5 months the periradicular tissue response was evaluated histologically. The results showed no periradicular inflammation adjacent to five of six root ends filled with MTA; also five of six root ends filled with MTA had a complete layer of cementum over the filling. In contrast, all root ends filled with amalgam showed periradicular inflammation, and cementum had not formed over the root-end filling material, although it was present over the cut root end. Based on these results and previous investigations, MTA is recommended as a root-end filling material in man.

journal_name

J Endod

journal_title

Journal of endodontics

authors

Torabinejad M,Pitt Ford TR,McKendry DJ,Abedi HR,Miller DA,Kariyawasam SP

doi

10.1016/S0099-2399(97)80051-9

subject

Has Abstract

pub_date

1997-04-01 00:00:00

pages

225-8

issue

4

eissn

0099-2399

issn

1878-3554

pii

S0099-2399(97)80051-9

journal_volume

23

pub_type

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