Abstract:
:Recently, a number of papers have brought up the issue of how to make cost-effectiveness (CE) studies stochastic, i.e. how to obtain confidence intervals for CE ratios. In this note we present a bootstrap procedure for estimating bias-corrected confidence intervals for CE ratios. The bootstrap procedure is tested in a simulation study based on the assumptions made in a recent paper by Wakker and Klaassen in this journal. We test two variants of CE ratio bootstrap confidence intervals. The first is a bootstrap analogue of the parametric method proposed by Wakker and Klaassen which gives results similar to those obtained with the parametric method. However, computing bootstrap confidence intervals directly for the CE ratio produce results closer to the predetermined significance level.
journal_name
Health Econjournal_title
Health economicsauthors
Tambour M,Zethraeus Ndoi
10.1002/(sici)1099-1050(199803)7:2<143::aid-hec322subject
Has Abstractpub_date
1998-03-01 00:00:00pages
143-7issue
2eissn
1057-9230issn
1099-1050pii
10.1002/(SICI)1099-1050(199803)7:2<143::AID-HEC322journal_volume
7pub_type
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