Effect of vaporized ethanol on [1-14C]pyruvate kinetics in mice using a four-compartment closed model.

Abstract:

:The effect of the inhalation of vaporized ethanol on injected [1-14C]pyruvate kinetics was studied in mice. The [1-14C]pyruvate kinetics were modelled by means of a four-compartment closed model, i.e. injected site, blood, periphery and expired 14CO2. The results show that the inhalation of vaporized ethanol can stimulate expiration of 14CO2. The compartmental analysis suggests that the stimulation of expiration of 14CO2 is attributed to the increased trans-membrane and trans-tissue processes.

journal_name

Pharmacol Res

journal_title

Pharmacological research

authors

Wu G

doi

10.1006/phrs.1997.0261

subject

Has Abstract

pub_date

1998-01-01 00:00:00

pages

49-55

issue

1

eissn

1043-6618

issn

1096-1186

pii

S1043-6618(97)90261-9

journal_volume

37

pub_type

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