Abstract：
:The impact of premorbid social and intellectual functioning in childhood and early adolescence on the developmental course of schizophrenia is not sufficiently understood. In a retrospective case study (93 consecutive in-patients, 43 males and 50 females) of first-episode psychosis occurring in adolescence, the relationship between premorbid adjustment and short-term therapeutic outcome under treatment conditions was examined. All of the patients had a DSM-III-R diagnosis of schizophrenia (n = 56) or schizo-affective disorder (n = 37). The mean age of the patients at the time of the study was 15.8 (SD = 1.0). Premorbid functioning during childhood and early adolescence was assessed by using the Cannon-Spoor et al. Premorbid Adjustment Scale (PAS) and studied with respect to its prognostic relevance for short-term therapeutic outcome (eight weeks) under neuroleptic treatment (350-700 mg Chlorpromazin dose equivalent). Criteria for clinical outcome were obtained from the study by Pearlson et al. (1989) which defines three grades (complete remission, partial remission and no response), according to the degree of positive symptomatology. Statistical analysis was based on nonparametric variance analysis. Patients with complete remission of positive symptoms after eight weeks of therapy had experienced far better premorbid adjustment in early adolescence and in childhood. Diagnosis and gender did not bias this result. Our data suggest that premorbid social functioning is a crucial variable with regard to therapeutic outcome in first-episode psychosis. Previous studies have reported a relation between poor premorbid functioning and negative symptoms. We found premorbid adjustment related to the course of positive symptoms.
journal_name
Eur Child Adolesc Psychiatryjournal_title
European child & adolescent psychiatryauthors
Amminger GP,Resch F,Mutschlechner R,Friedrich MH,Ernst Edoi
10.1007/BF00539928subject
Has Abstractpub_date
1997-12-01 00:00:00pages
212-8issue
4eissn
1018-8827issn
1435-165Xjournal_volume
6pub_type
杂志文章abstract：:Community-based mental health services for children and young people (CYP) can offer alternatives to inpatient settings and treat CYP in less restrictive environments. However, there has been limited implementation of such alternative models, and their efficacy is still inconclusive. Notably, little is known of the ex...
journal_title：European child & adolescent psychiatry
pub_type： 杂志文章
doi：10.1007/s00787-019-01420-7
更新日期：2020-12-01 00:00:00
abstract：OBJECTIVE:The aims of this study were to determine the prevalence of eating disorders (ED) in a representative school population of early adolescents of both sexes and to evaluate persistence and incidence after two years. METHOD:An initial sample of 1336 (mean age = 11.37) was assessed in a two-phase design. The Chil...
journal_title：European child & adolescent psychiatry
pub_type： 杂志文章
doi：10.1007/s00787-007-0625-0
更新日期：2007-12-01 00:00:00
abstract：:Attention Deficit and Hyperactive Disorder (ADHD) and Autism Spectrum Disorders (ASD) are frequent comorbid neurodevelopmental conditions and the overlap between both disorders remains to be delineated. A more complete understanding of the shared genetic and environmental factors is needed. Using a family-based method...
journal_title：European child & adolescent psychiatry
pub_type： 杂志文章
doi：10.1007/s00787-018-1206-0
更新日期：2019-02-01 00:00:00
abstract：:The greater burden of illness in youth with co-occurring attention-deficit/hyperactivity disorder (ADHD) and major depressive disorder (MDD) deserves further investigation, specifically regarding the influence of other psychiatric or medical conditions and the pharmacotherapies prescribed. A retrospective cohort desig...
journal_title：European child & adolescent psychiatry
pub_type： 杂志文章
doi：10.1007/s00787-014-0541-z
更新日期：2015-01-01 00:00:00
abstract：BACKGROUND:The impact of attention deficit hyperactive disorder (ADHD) in the Netherlands on health care utilisation, costs and quality of life of these children, as well as of their parents is unknown. OBJECTIVE:The aim of this study was to assess the direct medical costs of patients suffering from ADHD and their qua...
journal_title：European child & adolescent psychiatry
pub_type： 杂志文章
doi：10.1007/s00787-007-0603-6
更新日期：2007-08-01 00:00:00
abstract：:Evidence regarding the psychiatric morbidity of children born after Assisted Reproductive Techniques (ART) is inconsistent and limited. While normal mental well-being for ART children is usually reported, concerns are still being raised. Previous studies examine only some psychiatric disorders, but not all of them, ig...
journal_title：European child & adolescent psychiatry
pub_type： 杂志文章
doi：10.1007/s00787-019-01433-2
更新日期：2020-08-01 00:00:00
abstract：:Animal findings of long-term effects of maternal behaviors mediated via altered GR gene expression will, if translated into humans, have far reaching implications for our understanding of child and adolescent psychopathology. We have previously shown that mothers' self-reported stroking of their infants modifies assoc...
journal_title：European child & adolescent psychiatry
pub_type： 杂志文章
doi：10.1007/s00787-016-0886-6
更新日期：2017-03-01 00:00:00
abstract：:Worldwide, approximately one in eight children or adolescents suffers from a mental disorder. The present study was designed to determine the self-reported prevalence of mental health problems in children aged 6-11 years across eight European countries including Italy, France, Germany, the Netherlands, Lithuania, Bulg...
journal_title：European child & adolescent psychiatry
pub_type： 杂志文章
doi：10.1007/s00787-017-1073-0
更新日期：2018-06-01 00:00:00
abstract：:Callous-unemotional (CU) traits correlate with the severity and prognosis of conduct disorder in youth. The neuropeptide oxytocin (OT) has been linked to prosocial behaviors, including empathy and collaboration with others. This study discusses a possible role for OT in the biology of delinquent behavior. We hypothesi...
journal_title：European child & adolescent psychiatry
pub_type： 杂志文章
doi：10.1007/s00787-015-0765-6
更新日期：2015-12-01 00:00:00
abstract：:The impact of attention-deficit/hyperactivity disorder (ADHD) on health-related quality of life (HRQoL) is reported to be similar to that of other mental health and physical disorders. In this cross-sectional study, we hypothesized that children with ADHD and children with type 1 diabetes mellitus (T1DM) would have si...
journal_title：European child & adolescent psychiatry
pub_type： 杂志文章
doi：10.1007/s00787-015-0728-y
更新日期：2016-03-01 00:00:00
abstract：:This study aims at determining serum levels of tryptophan and other metabolites of the kynurenine pathway in children with attention deficit hyperactivity disorder (ADHD) compared to healthy controls. Such metabolites interact with glutamate receptors in the central nervous system, potentially modulating mechanisms th...
journal_title：European child & adolescent psychiatry
pub_type： 杂志文章
doi：10.1007/s00787-017-1002-2
更新日期：2017-12-01 00:00:00
abstract：:Selective examples from the literature on interethnic adoption are reviewed focusing on the various factors influencing adoption results. Late age at adoption, neglect and institutionalisation are risk factors for the psychological and behavioural problems in adoptees and families. The review also analyses methodologi...
journal_title：European child & adolescent psychiatry
pub_type： 杂志文章,评审
doi：10.1007/s00787-004-0358-2
更新日期：2004-04-01 00:00:00
abstract：:Children with autism-spectrum disorders (ASD) often fail laboratory false-belief tests of theory of mind (ToM). Yet how this impacts on their everyday social behavior is less clear, partly owing to uncertainty over which specific everyday conversational and social skills require ToM understanding. A new caregiver-repo...
journal_title：European child & adolescent psychiatry
pub_type： 杂志文章
doi：10.1007/s00787-008-0711-y
更新日期：2009-02-01 00:00:00
abstract：:The COVID-19 pandemic has caused unprecedented changes in the lives of 1.6 billion children and adolescents. First non-representative studies from China, India, Brazil, the US, Spain, Italy, and Germany pointed to a negative mental health impact. The current study is the first nationwide representative study to invest...
journal_title：European child & adolescent psychiatry
pub_type： 杂志文章
doi：10.1007/s00787-021-01726-5
更新日期：2021-01-25 00:00:00
abstract：:The aims of this study were, firstly, to study the association between parents' and teachers' ratings for the Finnish version of the Autism Spectrum Screening Questionnaire (ASSQ), secondly, to find out whether the original cut-off scores of the ASSQ identify primary school-aged children with Asperger syndrome (AS) or...
journal_title：European child & adolescent psychiatry
pub_type： 杂志文章
doi：10.1007/s00787-009-0044-5
更新日期：2009-08-01 00:00:00
abstract：:Despite ample evidence linking particular child temperament characteristics to behavior disorders later in life, there is currently a lack of temperament measures that can be used early, easily, and widely for screening purposes. To redress this gap, the current research aimed at developing a very brief scale of child...
journal_title：European child & adolescent psychiatry
pub_type： 杂志文章
doi：10.1007/s00787-019-01379-5
更新日期：2020-05-01 00:00:00
abstract：:Parents may develop symptoms of distress and dysfunctional cognitions in response to their child's exposure to traumatic events. Additionally, they may also be affected by their own traumatic experiences. This study investigated the frequency of traumatic experiences and of symptoms of posttraumatic stress and depress...
journal_title：European child & adolescent psychiatry
pub_type： 杂志文章
doi：10.1007/s00787-016-0821-x
更新日期：2016-09-01 00:00:00
abstract：:Academic impairment in individuals with attention-deficit/hyperactivity disorder (ADHD) is in part due to reduced motivation for academic tasks, which is likely to vary as a function of task characteristics. The current study employed a new questionnaire-the Child and Adolescent Motivational Profile (CHAMP)-to examine...
journal_title：European child & adolescent psychiatry
pub_type： 杂志文章
doi：10.1007/s00787-020-01494-8
更新日期：2020-03-10 00:00:00
abstract：:Autism spectrum disorder (ASD) is an early onset neurodevelopmental disorder. Evidence suggests that ASD patients have abnormalities in information processing. Event-related potential (ERP) technique can directly record brain neural activity in real time. P300 is a positive ERP component which can measure the neuroele...
journal_title：European child & adolescent psychiatry
pub_type： 杂志文章,meta分析
doi：10.1007/s00787-016-0880-z
更新日期：2017-02-01 00:00:00
abstract：:Anorexia nervosa (AN) and bulimia nervosa (BN) are complex disorders characterized by disordered eating behavior where the patient's attitude towards weight and shape, as well as their perception of body shape, are disturbed. Formal genetic studies on twins and families suggested a substantial genetic influence for AN...
journal_title：European child & adolescent psychiatry
pub_type： 杂志文章,评审
doi：10.1007/s00787-009-0085-9
更新日期：2010-03-01 00:00:00
abstract：:A substantial proportion of adolescents with attention deficit hyperactivity disorder (ADHD) do not appropriately adhere to prescribed treatments, especially to pharmacological treatments. It is important to disentangle the specific attitudes that contribute to treatment adherence. A 33-item questionnaire was applied ...
journal_title：European child & adolescent psychiatry
pub_type： 杂志文章
doi：10.1007/s00787-012-0277-6
更新日期：2012-07-01 00:00:00
abstract：:The objective of this study was to identify clinical subgroups in children with childhood autism and to examine comorbidity in each subgroup. The study was based on medical records of 30 inpatients referred to a specialist ward for children with pervasive developmental disorders. Eighteen consecutive patients with an ...
journal_title：European child & adolescent psychiatry
pub_type： 杂志文章
doi：10.1007/s007870050110
更新日期：2000-03-01 00:00:00
abstract：:The link between attention deficit/hyperactivity disorder (ADHD) and elevated body weight/obesity can be regarded as well established. Because oppositional defiant disorder (ODD)/conduct disorder (CD) has also been found to be associated with these characteristics and ADHD and ODD/CD often occur comorbidly, we investi...
journal_title：European child & adolescent psychiatry
pub_type： 杂志文章
doi：10.1007/s00787-013-0489-4
更新日期：2014-07-01 00:00:00
abstract：BACKGROUND:Children with conduct disorders and their families come into contact with a range of community and specialist agencies. METHODS:The aim of this study was to establish the lifetime service utilisation rates among children with conduct disorders from the Great Britain National Study (N = 10,438), and to exami...
journal_title：European child & adolescent psychiatry
pub_type： 杂志文章
doi：10.1007/s00787-003-0330-6
更新日期：2003-10-01 00:00:00
abstract：:Somatic disorders occur more often in adult psychiatric patients than in the general adult population. However, in child and adolescent psychiatry this association is unclear, mainly due to a lack of integration of existing data. To address this issue, we here present a systematic review on medical comorbidity in the ...
journal_title：European child & adolescent psychiatry
pub_type： 杂志文章,评审
doi：10.1007/s00787-017-1020-0
更新日期：2017-09-01 00:00:00
abstract：:A Dutch translation of the Strengths and Difficulties Questionnaire (SDQ) was made. In the first wave of data collection, self-report data of 11- to 16-yearolds (N = 970) were collected on the SDQ and other measures of psychopathology. In the second wave of data collection, extended versions of the SDQ were completed ...
journal_title：European child & adolescent psychiatry
pub_type： 杂志文章
doi：10.1007/s00787-003-0341-3
更新日期：2003-12-01 00:00:00
abstract：:Twin studies described a strongly heritable component of attention-deficit/hyperactivity disorder (ADHD) in children and adolescents. However, findings varied considerably between studies. In addition, ADHD presents with a high rate of comorbid disorders and associated psychopathology. Therefore, this literature revie...
journal_title：European child & adolescent psychiatry
pub_type： 杂志文章,评审
doi：10.1007/s00787-010-0097-5
更新日期：2010-03-01 00:00:00
abstract：OBJECTIVE:The aim of the study was to investigate capacity, demographic composition, and patterns of practice of Dutch child and adolescent psychiatrists, and to compare these findings with the results of a similar investigation in 1996. METHOD:A postal survey was sent out to all Dutch child and adolescent psychiatris...
journal_title：European child & adolescent psychiatry
pub_type： 杂志文章
doi：10.1007/s00787-005-0480-9
更新日期：2005-09-01 00:00:00
abstract：:Conduct disorder (CD) is a common and highly impairing psychiatric disorder of childhood and adolescence that frequently leads to poor physical and mental health outcomes in adulthood. The prevalence of CD is substantially higher in males than females, and partly due to this, most research on this condition has used a...
journal_title：European child & adolescent psychiatry
pub_type： 杂志文章,评审
doi：10.1007/s00787-018-1172-6
更新日期：2018-09-01 00:00:00
abstract：:The purpose of this study was to estimate the prevalence rates of probable posttraumatic stress disorder (PTSD) and depression and to explore potential risk factors among child and adolescent survivors 1 year following the 2008 Wenchuan earthquake. 3052 participants were administered the Child PTSD Symptom Scale, the ...
journal_title：European child & adolescent psychiatry
pub_type： 杂志文章
doi：10.1007/s00787-013-0400-3
更新日期：2013-09-01 00:00:00
