Evidence for rolling circle replication of Autographa californica M nucleopolyhedrovirus genomic DNA.

Abstract:

:Autographa californica M nucleopolyhedrovirus (AcMNPV) is a large ds DNA virus restricted to larval lepidopteran insect hosts. Using field inversion gel electrophoresis and digestion with a restriction enzyme which cuts the AcMNPV genome once, we detected multiple unit-length genome fragments from replicating viral DNA. Our data suggest that AcMNPV replicates in a head-to-tail manner via rolling circle replication.

journal_name

Arch Virol

journal_title

Archives of virology

authors

Oppenheimer DI,Volkman LE

doi

10.1007/s007050050229

subject

Has Abstract

pub_date

1997-01-01 00:00:00

pages

2107-13

issue

10

eissn

0304-8608

issn

1432-8798

journal_volume

142

pub_type

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