Abstract:
:Because xenon NMR is highly sensitive to the local environment, laser-polarized xenon could be a unique probe of living tissues. Realization of clinical and medical science applications beyond lung airspace imaging requires methods of efficient delivery of laser-polarized xenon to tissues, because of the short spin-lattice relaxation times and relatively low concentrations of xenon attainable in the body. Preliminary results from the application of a polarized xenon injection technique for in vivo 129Xe NMR/MRI are extrapolated along with a simple model of xenon transit to show that the peak local concentration of polarized xenon delivered to tissues by injection may exceed that delivered by respiration by severalfold.
journal_name
Proc Natl Acad Sci U S Aauthors
Goodson BM,Song Y,Taylor RE,Schepkin VD,Brennan KM,Chingas GC,Budinger TF,Navon G,Pines Adoi
10.1073/pnas.94.26.14725subject
Has Abstractpub_date
1997-12-23 00:00:00pages
14725-9issue
26eissn
0027-8424issn
1091-6490journal_volume
94pub_type
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journal_title:Proceedings of the National Academy of Sciences of the United States of America
pub_type: 杂志文章
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journal_title:Proceedings of the National Academy of Sciences of the United States of America
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更新日期:1985-05-01 00:00:00