The NMDA-receptor antagonist ketamine as an unconditioned stimulus in taste aversion learning.

abstract：:In four experiments the effects of serial compound conditioning on responding to a trace-conditioned CS were evaluated using a fear conditioning paradigm. The subjects were 18- and 25-day-old Sprague-Dawley rats, previously shown to exhibit little or no trace fear conditioning. Here, animals as young as 18 days of age...

journal_title：Neurobiology of learning and memory

authors： Hunt PS,Barnet RC,Shea ME,Baker EM

更新日期：2006-11-01 00:00:00

abstract：:Neuronal plasticity and neurogenesis occur in the adult hippocampus and in other brain structures such as the olfactory bulb and often involve the neural cell adhesion molecule NCAM. During an olfactory associative discrimination learning task, NCAM polysialylation triggers neuronal plasticity in the adult hippocampus...

journal_title：Neurobiology of learning and memory

authors： Mione J,Manrique C,Duhoo Y,Roman FS,Guiraudie-Capraz G

更新日期：2016-04-01 00:00:00

abstract：:It has been proposed that normal waking levels of acetylcholine (ACH) are important for initial memory acquisition, and that decreased ACH is critical for memory consolidation. Sleep is thought to benefit memory consolidation in part due to the predominance of low ACH levels observed during non-rapid eye movement slee...

journal_title：Neurobiology of learning and memory

authors： Tucker MA,Taylor K,Merchant R,George S,Stoddard C,Kopera K

更新日期：2018-11-01 00:00:00

abstract：:Extensive evidence indicates that benzodiazepine receptors in the amygdala are involved in regulating memory consolidation. Recent findings indicate that many other drugs and hormones influence memory through selective activation of the basolateral amygdala nucleus (BLA). This experiment examined whether the memory-mo...

journal_title：Neurobiology of learning and memory

authors： Da Cunha C,Roozendaal B,Vazdarjanova A,McGaugh JL

更新日期：1999-07-01 00:00:00

abstract：:The specific sigma-receptor agonist (+)-SKF 10047 and antagonist BD 1047 were used to investigate whether this receptor was involved in passive-avoidance training in the day-old chick. We found 300 microM (+)-SKF 10047 to be amnesic when injected into the lobus parolfactorius 5 h after training (p < .01). Higher or lo...

journal_title：Neurobiology of learning and memory

authors： Freeman FM,Young IG

更新日期：2001-05-01 00:00:00

abstract：:When trained to peck a selected position in a sagittally-oriented series of identical food containers, and then required to generalize to an identical series rotated by 90°, chicks identify as correct only the target position from the left end, while choosing the right one at chance. Here we show that when accustomed ...

journal_title：Neurobiology of learning and memory

authors： Rugani R,Vallortigara G,Vallini B,Regolin L

更新日期：2011-03-01 00:00:00

abstract：:Formation of long-term memories requires coordinated gene expression, which can be regulated at transcriptional, post-transcriptional, and translational levels. Post-transcriptional stabilization and destabilization of mRNAs provides precise temporal and spatial regulation of gene expression, which is critical for con...

journal_title：Neurobiology of learning and memory

authors： Lee YS,Lee JA,Kaang BK

更新日期：2015-10-01 00:00:00

abstract：:Numerous experiments using ex vivo electrophysiology suggest that mammalian learning and memory involves regulation of voltage-gated ion channels in terms of changes in function. Yet, little is known about learning-related regulation of voltage-gated ion channels in terms of changes in expression. In two experiments, ...

journal_title：Neurobiology of learning and memory

authors： Fuchs JR,Darlington SW,Green JT,Morielli AD

更新日期：2017-07-01 00:00:00

abstract：:Most models of human and animal learning assume that learning is proportional to the discrepancy between a delivered outcome and the outcome predicted by all cues present during that trial (i.e., total error across a stimulus compound). This total error reduction (TER) view has been implemented in connectionist and ar...

journal_title：Neurobiology of learning and memory

authors： Witnauer JE,Urcelay GP,Miller RR

更新日期：2014-02-01 00:00:00

abstract：:Accumulating evidence indicates that homeostatic plasticity mechanisms dynamically adjust synaptic strength to promote stability that is crucial for memory storage. Our previous studies have shown that prior training in conditioned taste aversion (CTA) prevents the subsequent induction of long-term potentiation (LTP) ...

journal_title：Neurobiology of learning and memory

authors： Rivera-Olvera A,Nelson-Mora J,Gonsebatt ME,Escobar ML

更新日期：2018-10-01 00:00:00

abstract：:Veridical detection of safety versus danger is critical to survival. Learned signals for safety inhibit fear, and so when presented, reduce fear responses produced by danger signals. This phenomenon is termed conditioned inhibition of fear. Here, we report that CS+/CS- fear discrimination conditioning over 5 days in r...

journal_title：Neurobiology of learning and memory

authors： Foilb AR,Flyer-Adams JG,Maier SF,Christianson JP

更新日期：2016-10-01 00:00:00

abstract：:Different exercise paradigms show differential effects on various forms of memory. We hypothesize that the differential effects of exercises on memory performance are caused by different neuroplasticity changes in relevant brain regions in response to different exercise trainings. We examined the effects of treadmill ...

journal_title：Neurobiology of learning and memory

authors： Lin TW,Chen SJ,Huang TY,Chang CY,Chuang JI,Wu FS,Kuo YM,Jen CJ

更新日期：2012-01-01 00:00:00

abstract：:Much has been said about how significant life events modulate our response to stimuli that are integral to those events. However, we know less about the more general consequences of these events, that is, how they affect subsequent learning abilities that are seemingly irrelevant to the initial event. Here, it is prop...

journal_title：Neurobiology of learning and memory

authors： Shors TJ

更新日期：2006-03-01 00:00:00

abstract：:The beneficial effects of caloric restriction (CR) on health and life expectancy are well documented, although its ability to slow down age-dependent cognitive decline and the underlying biochemical changes remains unclear. Therefore, the aim of this study was to investigate the effects of CR on spatial memory in aged...

journal_title：Neurobiology of learning and memory

authors： Rojic-Becker D,Portero-Tresserra M,Martí-Nicolovius M,Vale-Martínez A,Guillazo-Blanch G

更新日期：2019-12-01 00:00:00

abstract：:Previous research has suggested that the disruption to memory-task performance seen following acute exposure to 3,4-methylenedioxymethaphemtamine (MDMA) with rats might best be characterized as reference memory impairment rather than a working memory impairment. The current study specifically compared the effects of M...

journal_title：Neurobiology of learning and memory

authors： Kay C,Harper DN,Hunt M

更新日期：2010-02-01 00:00:00

abstract：:Based on computational models of the hippocampus, it has been suggested that a possible mechanism for memory retrieval is pattern completion, wherein an autoassociative network recalls previous patterns of activity given noisy or degraded cues. However, there are few behavioral data examining pattern completion per se...

journal_title：Neurobiology of learning and memory

authors： Kirwan CB,Gilbert PE,Kesner RP

更新日期：2005-01-01 00:00:00

abstract：:Testosterone (T) may enhance cognitive performance. However, its mechanisms are not well understood. First, we hypothesized that if T's effects are mediated in part through actions of its 5alpha-reduced metabolites, dihydrotestosterone (DHT) and/or 3alpha-androstanediol (3alpha-diol) in the hippocampus, then T, DHT, a...

journal_title：Neurobiology of learning and memory

authors： Edinger KL,Frye CA

更新日期：2007-01-01 00:00:00

abstract：:Brief physical exercise enhances memories for neutral events, and recently has been shown to modulate fear learning in animals. To date there is no evidence pertaining to the impact of exercise on emotional memories in humans. Accordingly, this study investigated the role of brief exercise in the development of emotio...

journal_title：Neurobiology of learning and memory

authors： Keyan D,Bryant RA

更新日期：2017-05-01 00:00:00

abstract：:Memories for daily events require that individuals integrate initial fragile traces of events over time. Recent evidence suggests that reward anticipation enhances memory performance and amplifies frontal theta activity for remembered items vs. forgotten items. However, little is known about how incidental rewards aft...

journal_title：Neurobiology of learning and memory

authors： Pu M,Yu R

更新日期：2019-02-01 00:00:00

abstract：:Rodents exhibit neophobia for novel tastes, demonstrated by an initial reluctance to drink novel-tasting, potentially-aversive solutions. Taste neophobia attenuates across days if the solution is not aversive, demonstrated by increased consumption as the solution becomes familiar. This attenuation of taste neophobia i...

journal_title：Neurobiology of learning and memory

authors： Grau-Perales AB,Levy ERJ,Fenton AA,Gallo M

更新日期：2019-01-01 00:00:00

abstract：:Mixed results with the synthetic β-adrenergic receptor blocker, propranolol, have been reported in human populations with regards to its therapeutic efficacy for PTSD treatments targeting the memory reconsolidation process. Stress alters the ability to form and maintain memory, but whether the causal neuronal mechanis...

journal_title：Neurobiology of learning and memory

authors： Hughes E,Shymansky T,Sunada H,Lukowiak K

更新日期：2016-12-01 00:00:00

abstract：:Previous evidence suggests that a high-salt (HS) diet may increase oxidative stress and contribute to the development of hypertension that is already present. Oxidative stress is thought to play a critical role in the development of neurodegenerative diseases. Lower dietary sodium intake putatively contributes to a lo...

journal_title：Neurobiology of learning and memory

authors： Liu YZ,Chen JK,Li ZP,Zhao T,Ni M,Li DJ,Jiang CL,Shen FM

更新日期：2014-10-01 00:00:00

abstract：:The authors evaluate a mapping of Rescorla and Wagner's (1972) behavioral model of classical conditioning onto the cerebellar substrates for motor reflex learning and illustrate how the limitations of the Rescorla-Wagner model are just as useful as its successes for guiding the development of new psychobiological theo...

journal_title：Neurobiology of learning and memory

authors： Gluck MA,Allen MT,Myers CE,Thompson RF

更新日期：2001-11-01 00:00:00

abstract：:ADHD and its subclinical symptoms have been associated with both disturbed sleep and weakened overnight memory consolidation. As sleep spindle activity during NREM sleep plays a key role in both sleep maintenance and memory consolidation, we examined the association between subclinical ADHD symptoms and sleep spindle ...

journal_title：Neurobiology of learning and memory

authors： Merikanto I,Kuula L,Makkonen T,Halonen R,Lahti J,Heinonen K,Räikkönen K,Pesonen AK

更新日期：2019-01-01 00:00:00

abstract：:Transcriptional changes in the hippocampus are required for memory formation, and these changes are regulated by numerous post-translational modifications of chromatin-associated proteins. One of the epigenetic marks that has been implicated in memory formation is histone 3 lysine 4 trimethylation (H3K4me3), and this ...

journal_title：Neurobiology of learning and memory

authors： Collins BE,Sweatt JD,Greer CB

更新日期：2019-05-01 00:00:00

abstract：:Sex differences in learned fear expression and extinction involve the medial prefrontal cortex (mPFC). We recently demonstrated that enhanced learned fear expression during auditory fear extinction and its recall is linked to persistent theta activation in the prelimbic (PL) but not infralimbic (IL) cortex of female r...

journal_title：Neurobiology of learning and memory

authors： Fenton GE,Halliday DM,Mason R,Bredy TW,Stevenson CW

更新日期：2016-11-01 00:00:00

abstract：:The effects of selective cholinergic cell loss within the basal forebrain (BF) were determined using a task that requires shifting of attention between two visual stimuli. Discriminability between two stimuli and response bias were determined in young and old F-344 rats given BF injections of IgG-192 saporin (100 ng)....

journal_title：Neurobiology of learning and memory

authors： Stoehr JD,Mobley SL,Roice D,Brooks R,Baker LM,Wiley RG,Wenk GL

更新日期：1997-05-01 00:00:00

abstract：:Human studies of sleep and cognition have established thatdifferent sleep stages contribute to distinct aspects of cognitive and emotional processing. However, since the majority of these findings are based on single-night studies, it is difficult to determine whether such effects arise due to individual, between-subj...

journal_title：Neurobiology of learning and memory

authors： Lerner I,Lupkin SM,Corter JE,Peters SE,Cannella LA,Gluck MA

更新日期：2016-10-01 00:00:00

abstract：:The neurophysiological basis for context conditioning is conceptually problematic because neurophysiological descriptions of activity-dependent (associative) forms of neuronal plasticity uniformly assume that a specific temporal relationship between signals is necessary for memory induction. In the present experiments...

journal_title：Neurobiology of learning and memory

authors： Talk AC,Muzzio IA,Matzel LD

更新日期：1999-09-01 00:00:00

abstract：:The dynamics of learning in the Active Avoidance test was analyzed at the trials level as well as at the level of daily sessions, each comprising numerous trials. The two scales (large scale for the sessions and small scale for the trials) were demonstrated to be mutually independent. The intermediate derived scales (...

journal_title：Neurobiology of learning and memory

authors： Giuliani A,Mancini AM,Ghirardi O,Ramacci MT,Voronina T,Sirabella P,Colosimo A

更新日期：1996-01-01 00:00:00