Abstract：
BACKGROUND:Intraoperative measurements of local intracapillary hemoglobin oxygenation of the human cochlea via the round window membrane have been shown to be possible using the Erlangen microlight-guided spectrophotometer. The aim of the present study was to develop a new microlight guide suitable for measurements in the round window niche and to evaluate electrophysiologically the possible impact of the procedure on the cochlea. METHODS:Measurements were made for wavelengths of 450 to 900 nm at a total power of 5.3 mW. The exit diameter of the light guide was 200 microns and the angle used was 20 degrees. The recording depth was about 250 microns. The atraumatic character of the spectrophotometry was demonstrated by monitoring the compound action potential (CAP) threshold tuning curve from 1 to 34 kHz in ketanest-anesthetized guinea pigs. RESULTS:CAP thresholds remained constant (0.3 +/- 3.9 dB SPL) during 3 to 30 min of exposure to the light. CONCLUSIONS:These results suggest that the spectrophotometry may be useful as a new technique for intraoperative monitoring of intracapillary hemoglobin without causing physiological deterioration of the cochlea.
journal_name
HNOjournal_title
HNOauthors
Leuwer R,Maier H,Gummer AWdoi
10.1007/s001060050112subject
Has Abstractpub_date
1997-05-01 00:00:00pages
372-7issue
5eissn
0017-6192issn
1433-0458journal_volume
45pub_type
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