Sodium urate arthritis: effects on the sensory properties of articular afferents in the chicken.

abstract：:We aimed to investigate whether small-fibre pathology, a common skin biopsy finding in patients with fibromyalgia, implies clinically important abnormalities of somatosensory system function and verify whether it is associated with voltage-gated sodium channel variants. In 57 consecutively enrolled patients with fibro...

journal_title：Pain

authors： Fasolino A,Di Stefano G,Leone C,Galosi E,Gioia C,Lucchino B,Terracciano A,Di Franco M,Cruccu G,Truini A

更新日期：2020-10-01 00:00:00

abstract：:Percentage of pain intensity difference (PercentPID) is a recognized way of evaluating pain relief with an 11-point numerical rating scale (NRS) but is not without flaws. A new metric, the slope of relative pain intensity difference (SlopePID), which consists in dividing PercentPID by the time between 2 pain measureme...

journal_title：Pain

authors： Chauny JM,Paquet J,Lavigne G,Marquis M,Daoust R

更新日期：2016-02-01 00:00:00

abstract：:The assessment and development of pain in children is reviewed in the first part of a two-part series. Assessment of pain in children has relied on self-report measures that have included visual analogue procedures using concrete stimuli for ratings. Behavioral assessment procedures are more sophisticated, but researc...

journal_title：Pain

authors： Lavigne JV,Schulein MJ,Hahn YS

更新日期：1986-11-01 00:00:00

abstract：:We assessed for the first time the long-term maintenance of repetitive transcranial magnetic stimulation (rTMS)-induced analgesia in patients with chronic widespread pain due to fibromyalgia. Forty consecutive patients were randomly assigned, in a double-blind fashion, to 2 groups: one receiving active rTMS (n=20) and...

journal_title：Pain

authors： Mhalla A,Baudic S,de Andrade DC,Gautron M,Perrot S,Teixeira MJ,Attal N,Bouhassira D

更新日期：2011-07-01 00:00:00

abstract：:Mechanisms of hypnotic analgesia were investigated by examining changes in the R-III, a nociceptive spinal reflex, during hypnotic reduction of pain sensation and unpleasantness. The R-III was measured in 15 healthy volunteers who gave VAS-sensory and VAS-affective ratings of an electrical stimulus during conditions o...

journal_title：Pain

authors： Kiernan BD,Dane JR,Phillips LH,Price DD

更新日期：1995-01-01 00:00:00

abstract：:The tricyclic antidepressant drugs (TCAs) are commonly used in the treatment of chronic, especially neuropathic, pain. We evaluated their possible effect on a new model of neuropathic pain-related behaviour induced by ligatures tied loosely around the common sciatic nerve. The effects of 3 TCAs with different monoamin...

journal_title：Pain

authors： Ardid D,Guilbaud G

更新日期：1992-05-01 00:00:00

abstract：:The purpose of this study was to determine if some commonly used admission variables could predict treatment outcome on a multidisciplinary pain center. Specifically, it was designed as a prospective study of an index proposed by Maruta et al. The subjects were 104 patients. The 4 outcome measures used were staff judg...

journal_title：Pain

authors： Aronoff GM,Evans WO

更新日期：1982-09-01 00:00:00

abstract：:Systemic opioid dosing until adequate analgesia in neuropathic pain may involve intolerable and untreatable side effects. Peripheral opioid receptor mechanisms may participate in the antinociceptive effect of systemic morphine. We evaluated the effect of peripherally injected morphine alone, and the ability of the fun...

journal_title：Pain

authors： Martinez V,Christensen D,Kayser V

更新日期：2002-10-01 00:00:00

abstract：:Fibromyalgia (FM) syndrome represents a great challenge for clinicians and researchers because the efficacy of currently available treatments is limited. This study examined the efficacy of mindfulness-based stress reduction (MBSR) for reducing functional impairment as well as the role of mindfulness-related construct...

journal_title：Pain

authors： Pérez-Aranda A,Feliu-Soler A,Montero-Marín J,García-Campayo J,Andrés-Rodríguez L,Borràs X,Rozadilla-Sacanell A,Peñarrubia-Maria MT,Angarita-Osorio N,McCracken LM,Luciano JV

更新日期：2019-11-01 00:00:00

abstract：:The present study investigated the role of micro, delta, and kappa receptors within the RVM in mediating expression of conditional hypoalgesia (CHA). Five groups of rats with RVM cannulae were given daily sessions of paired or unpaired presentations of an auditory CS (white noise) and foot shock across three consecuti...

journal_title：Pain

authors： Foo H,Helmstetter FJ

更新日期：1999-12-01 00:00:00

abstract：:A fundamental question for placebo research is whether such responses are a predisposition, quantifiable by brain characteristics. We examine this issue in chronic back pain (CBP) patients who participated in a double-blind brain imaging (functional magnetic resonance imaging) clinical trial. We recently reported that...

journal_title：Pain

authors： Hashmi JA,Baria AT,Baliki MN,Huang L,Schnitzer TJ,Apkarian VA

更新日期：2012-12-01 00:00:00

abstract：:Somatovisceral convergence was demonstrated in recordings from 15 of 16 spinothalamic tract cells in the lower thoracic spinal cords of anesthetized monkeys. Inputs were produced by mechanical (or sometimes electrical) stimulation of the skin over the lower trunk and by electrical stimulation of the greater splanchnic...

journal_title：Pain

authors： Foreman RD,Hancock MB,Willis WD

更新日期：1981-10-01 00:00:00

abstract：:The associative network theory of memory [2] is outlined along with the concepts of mood congruity and state dependent learning. Two experiments are reported which investigate the occurrence of these effects where memory for pain is concerned. In experiment 1 the performance of 25 chronic pain patients was compared wi...

journal_title：Pain

authors： Pearce SA,Isherwood S,Hrouda D,Richardson PH,Erskine A,Skinner J

更新日期：1990-11-01 00:00:00

abstract：:A wide range of environmental stimuli have been shown to induce antinociception. Investigation of the brain regions contributing to environmentally induced antinociception (EIA) has focused primarily on the effect of disrupting neural transmission at various CNS sites. In contrast, the present study analyzed changes i...

journal_title：Pain

authors： Morgan MM,Fields HL

更新日期：1993-01-01 00:00:00

abstract：:The purpose of this study was to assess the hypothesis that pain and depression negatively impact the cognitive functioning of individuals with rheumatoid arthritis (RA). One hundred twenty-one community-dwelling RA patients (ages 34-84) completed a battery of cognitive tasks and multiple measures of pain and depressi...

journal_title：Pain

authors： Brown SC,Glass JM,Park DC

更新日期：2002-04-01 00:00:00

abstract：:The habituation to sensory stimuli of different modalities is reduced in migraine patients. However, the habituation to pain has never been evaluated. Our aim was to assess the nociceptive pathway function and the habituation to experimental pain in patients with migraine. Scalp potentials were evoked by CO(2) laser s...

journal_title：Pain

authors： Valeriani M,de Tommaso M,Restuccia D,Le Pera D,Guido M,Iannetti GD,Libro G,Truini A,Di Trapani G,Puca F,Tonali P,Cruccu G

更新日期：2003-09-01 00:00:00

abstract：:Capsaicin has been used extensively as an experimental tool and in traditional and proprietary topical medications for acute soft tissue injuries. More recently it has been prescribed for several chronic pain conditions where it is usually administered topically for periods of several weeks. Here we have studied the c...

journal_title：Pain

authors： McMahon SB,Lewin G,Bloom SR

更新日期：1991-03-01 00:00:00

abstract：:In a double-blind, cross-over study, ibuprofen (600 mg), a peripherally-acting selective kappa-opioid receptor agonist (7.5 mg), or placebo were given orally in experiments on healthy volunteers 1 h before assessment of pain thresholds to radiant heat and of pain ratings to controlled mechanical impact stimuli. Mechan...

journal_title：Pain

authors： Bickel A,Dorfs S,Schmelz M,Forster C,Uhl W,Handwerker OH

更新日期：1998-06-01 00:00:00

abstract：:In male rats, carrageenan (CAR)-induced inflammation or exposure to a selective protein kinase C epsilon (PKC epsilon ) agonist (psi epsilon RACK) produces prolongation of the hyperalgesia induced by a subsequent exposure to an inflammatory mediator, a phenomenon referred to as hyperalgesic priming. Since many chronic...

journal_title：Pain

authors： Joseph EK,Parada CA,Levine JD

更新日期：2003-09-01 00:00:00

abstract：:Pain is generally considered to have a sensory and an affective component. Clinical research has suggested that morphine more potently attenuates the affective component as compared to the sensory component. Because preclinical nociception models typically focus on the sensory component of nociception, and do not asse...

journal_title：Pain

authors： van der Kam EL,De Vry J,Schiene K,Tzschentke TM

更新日期：2008-06-01 00:00:00

abstract：:Excessive pain during medical procedures performed in unanesthetized patients is frequently reported, but can be reduced with virtual reality (VR) distraction. Increasing the person's illusion of going into the virtual world may increase how effectively VR distracts pain. Healthy volunteers aged 18-20 years participat...

journal_title：Pain

authors： Hoffman HG,Sharar SR,Coda B,Everett JJ,Ciol M,Richards T,Patterson DR

更新日期：2004-09-01 00:00:00

abstract：:This experiment had three goals: 1. To identify the basis of sucking-induced analgesia in healthy, term, newborn humans undergoing the painful, routine, procedure of heel lance and blood collection. 2. To evaluate how taste-induced and sucking-induced analgesias combine to combat pain. 3. To determine whether facial g...

journal_title：Pain

authors： Blass EM,Watt LB

更新日期：1999-12-01 00:00:00

abstract：:There is evidence of greater opioid prescription to individuals in the United States with mental health conditions. Whether these associations generalize beyond the US prescription environment and to familial mental health and socioeconomic status (SES) has not been examined comprehensively. This study estimated assoc...

journal_title：Pain

authors： Quinn PD,Rickert ME,Franck J,Sariaslan A,Boersma K,Lichtenstein P,Larsson H,D'Onofrio BM

更新日期：2019-11-01 00:00:00

abstract：:In a consecutive series of 227 psychiatric hospital admissions, data were recorded in respect of the complaint of pain. Eighty-six (38%) had pain. Fourty-four (19%) mentioned it spontaneously and 49 (22%) had no relevant physical cause. Women were affected more often than men (P less than 0.01) and tended to complain ...

journal_title：Pain

authors： Delaplaine R,Ifabumuyi OI,Merskey H,Zarfas J

更新日期：1978-04-01 00:00:00

abstract：:Migraine headache is one of the most common neurological disorders. The pathological conditions that directly initiate afferent pain signaling are poorly understood. In trigeminal neurons retrogradely labeled from the cranial meninges, we have recorded pH-evoked currents using whole-cell patch-clamp electrophysiology....

journal_title：Pain

authors： Yan J,Edelmayer RM,Wei X,De Felice M,Porreca F,Dussor G

更新日期：2011-01-01 00:00:00

abstract：:Do contrasting neuropathic pain diagnoses share common pathophysiological mechanisms? Selective breeding was used to derive rat lines with a common genetic background but a striking difference in the degree of spontaneous pain behavior expressed in the neuroma model of neuropathic pain (HA rats (high autotomy) and LA ...

journal_title：Pain

authors： Ziv-Sefer S,Raber P,Barbash S,Devor M

更新日期：2009-11-01 00:00:00

abstract：:Below-level central neuropathic pain (CNP) affects a large proportion of spinal cord injured individuals. To better define the dynamic changes of the spinal cord neural network contributing to the development of CNP after spinal cord injury (SCI), we characterized the morphological and behavioral correlates of CNP in ...

journal_title：Pain

authors： Nees TA,Tappe-Theodor A,Sliwinski C,Motsch M,Rupp R,Kuner R,Weidner N,Blesch A

更新日期：2016-03-01 00:00:00

abstract：:Hip disorder patients typically present with extensive pain referral and hyperalgesia. To better understand underlying mechanisms, an experimental hip pain model was established in which pain referrals and hyperalgesia could be studied under standardized conditions. In 16 healthy subjects, pain was induced by hyperton...

journal_title：Pain

authors： Izumi M,Petersen KK,Arendt-Nielsen L,Graven-Nielsen T

更新日期：2014-04-01 00:00:00

abstract：:This study examined the adaptational classification stability of the multidimensional pain inventory (MPI) in two samples of female fibromyalgia syndrome patients. Retest resulted in one-third of patients being assigned to a different classification. Twenty patients had four repeated MPI assessments over a 10-month pe...

journal_title：Pain

authors： Broderick JE,Junghaenel DU,Turk DC

更新日期：2004-05-01 00:00:00

abstract：:Changes in perception of pure thermal stimuli delivered to the hand at threshold intensity were observed during ischemic nerve block in 27 healthy subjects in order to study the significance of unmyelinated cutaneous cold receptors for thermal sensibility. Paresthesias and an increasing feeling of numbness were follow...

journal_title：Pain

authors： Fruhstorfer H

更新日期：1984-12-01 00:00:00