Abstract:
:The effects of A. indica (AI, Neem) were evaluated on tests of humoral and cell-mediated immune responses after 3 weeks of oral AI (leaf extract) treatment in ovalbumin immunized mice. At the dose levels tested, AI (10, 30 or 100 mg/kg), had no appreciable influence on different organ (liver, spleen, thymus)/body weight indices, when compared to controls. In tests for humoral immune responses, AI (100 mg/kg) treated mice had higher (1) IgM and IgG levels, and (b) anti-ovalbumin antibody titres, when compared to the vehicle treated group. In tests for cell-mediated immune responses, there was an enhancement (%) of (a) macrophage migration inhibition, and (b) footpad thickness after AI (100 mg/kg) treatment. These results are discussed in light of the possible immunopotentiating effects of AI.
journal_name
Indian J Exp Bioljournal_title
Indian journal of experimental biologyauthors
Ray A,Banerjee BD,Sen Psubject
Has Abstractpub_date
1996-07-01 00:00:00pages
698-701issue
7eissn
0019-5189issn
0975-1009journal_volume
34pub_type
杂志文章abstract::Ten oleaginous yeasts were isolated from sources like fruits, flowers, curd whey and soil samples. Lipid production varied from 24 to 71.2% of dry weight of cell biomass. Strain Y-1, which was isolated from curd whey, produced the highest amount of lipid. It was identified belonging to the genus Candida. The optimal c...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:1997-03-01 00:00:00
abstract::Leukotrienes play a part in inflammatory response. The unique role of the enzyme 5-lipoxygenase (5-LOX) in the production of leukotrienes makes it a likely therapeutic target for inflammatory conditions like asthma, rheumatoid arthritis, psoriasis, and inflammatory bowel disease (IBD). The aim of the present study was...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:2004-07-01 00:00:00
abstract::Ascorbic acid treatment in arsenic trioxide treated rats increased arsenic excretion, inhibited lipid peroxidation, improved GSH status, regulated GSSG turnover and also restored glutathione-S-transferases activity in liver and kidney. Suitable mechanisms leading to ascorbic acid protection have been discussed. Upregu...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:2007-04-01 00:00:00
abstract::The experimental diets (40% protein) contained graded levels of tryptophan (0.60, 0.75, 1.00, 1.25, 1.50, 1.75%) of dietary protein. Each test diet was fed to triplicate groups of mrigal fry twice daily at 10% of the total biomass for 8 weeks. The dietary tryptophan requirement was estimated by plotting weight gain ag...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:2003-11-01 00:00:00
abstract::The role of acetylation in the antiglycating and anticataract effects of aspirin (ASA) is explored by comparing ASA's effects with that of sodium salicylate (SS), a nonacetyl analog of ASA, on cataract development in diabetic rats. Streptozocin diabetic rats were provided with either ASA or SS, orally, for 24 weeks. A...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:1998-07-01 00:00:00
abstract::In the present study HD-03, a herbal formulation was investigated for its anti-cholestatic activity in TAA-induced cholestasis in anaesthetized guinea pigs. Administration of TAA at a dose of 100 mg/kg body wt significantly reduced the bile flow, bile acid and bile salt excretion. Pretreatment with HD-03 at a dose of ...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:1999-04-01 00:00:00
abstract::Effect of polyherbal formulation Ambrex was evaluated in butylated hydroxytoluene (BHT) induced toxicity of lungs and liver in rats. Toxicity was produced by administering BHT (500 mg/kg/day) for 3 days. Lung damage was evidenced by elevated levels of broncho alveolar lavage fluid (BAL) parameters such as protein, lac...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:2003-11-01 00:00:00
abstract::Leaves of P. sativum the double mutant genotype tendril-less (tl) leaflet-development (lld), due to the action of lld mutation, produce many leaflets that are aborted at different stages of development. Morphological, vein pattern and histological observations showed that aborted leaflets became cup/bell/trumpet (cup)...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:2013-06-01 00:00:00
abstract::Ricin, a glycoprotein from castor oil seeds, is specifically toxic to Kupffer cells and at low doses it leaves parenchymal cells comparatively unaffected. At a dose of approximately 1.5 microgram/100 g body weight, ricin significantly increases the hepatic antioxidant enzyme system in rats within 24 hr. Superoxide dis...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:1994-05-01 00:00:00
abstract::Pulp and paper mill effluents pollute water, air and soil, causing a major threat to the environment. Several methods have been attempted by various researchers throughout the world for the removal of colour from pulp and paper mill effluents. The biological colour removal process uses several classes of microorganism...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章,评审
doi:
更新日期:2003-11-01 00:00:00
abstract::Oral administration of ethanol extract of N. sativa seeds (300 mg/kg body weight/day) to streptozotocin induced diabetic rats for 30 days significantly reduced the elevated levels of blood glucose, lipids, plasma insulin and improved altered levels of lipid peroxidation products (TBARS and hydroperoxides) and antioxid...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:2006-09-01 00:00:00
abstract::Pseudomonas aeruginosa MCCB 123 was grown in a synthetic medium for beta-1,3 glucanase production. From the culture filtrate, beta-1,3 glucanase was purified with a molecular mass of 45 kDa. The enzyme was a metallozyme as its beta-1,3 glucanase activity got inhibited by the metal chelator EDTA. Optimum pH and tempera...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:2014-01-01 00:00:00
abstract::Effects of Indian red scorpion (M. tamulus concanesis; MBT) venom on the compound action potential (CAP) of sciatic nerve in vitro were examined. MBT venom (0.1-6.0 micrograms/ml) prolonged the repolarization time and refractory period of the CAP in a concentration-dependent manner with maximal potentiation occurring ...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:1998-11-01 00:00:00
abstract::Adequate expression of Bt (Bacillus thuringiensis) toxins and purity of seeds of Bt-transgenic cottons are important for controlling bollworms, and thereby increasing the cotton productivity. Therefore, we examined the variability in expression of Bt toxin proteins in the seeds and in leaves of different cotton (Gossy...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:2016-04-01 00:00:00
abstract::Genotoxicity study of synthetic progestin lynestrenol, was carried out on mouse bone marrow cells using sister chromatid exchanges (SCEs) and chromosomal aberrations (CAs) as parameters. Lynestrenol was studied at three different doses (6.87, 13.75 and 27.50 mg/kg body wt.). SCE and CA increased significantly as compa...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:2005-03-01 00:00:00
abstract::Cheek gland secretions from sexually mature and reproductively active male and female laboratory rats (Wister strain), Rattus norvegicus albinus were analysed by gas chromatography/mass spectroscopy. Alkanes, aliphatic acids esters and alcohols were identified in the secretions. Cheek gland preparation from males cont...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:2001-09-01 00:00:00
abstract::Cognitive disorders in mankind are not uncommon. Apart from neurodegenerative diseases such as Alzheimer's (AD), various stresses also affect cognitive functions. Plants are known to be potential source of compounds that ameliorate several diseases including cognitive impairment. Here, we evaluated effect of aqueous e...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:2016-02-01 00:00:00
abstract::Naturally occurring alkaloids are nitrogenous compounds that constitute the pharmacogenically active basic principles of flowering plants. Alkaloids are classified into several biogenically related groups. Tobacco alkaloids are metabolised from polyamines and diamines putrescine and cadaverine. N-methyl transferase is...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章,评审
doi:
更新日期:2000-11-01 00:00:00
abstract::Four plants having known medicinal properties were screened for inhibition of goatpox virus (GTPV) replication in vitro. Of the 4 plants, extract of Acacia arabica (Babul) and Eugenia jambolana (Jamun) leaves had inhibition (%) 99.70 and 99.92 at their maximum non toxic concentrations, 99.93 +/- 0.38 and 1999.73 +/- 0...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:2008-02-01 00:00:00
abstract::Two wheat varieties, T. durum (HD 4502) and T. aestivum (Kalyansona) were examined for photosynthesis rate and contents of sugars and rubisco protein in the flag leaf, at forenoon and afternoon at anthesis stage. A decrease in photosynthesis rate was observed in the afternoon compared to forenoon in both the varieties...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:2001-11-01 00:00:00
abstract::Administration of bromocriptine (Bc), an ergot derivative having dopamine receptor agonist activity, to rats on day 1-5 of pregnancy prevented implantation of blastocysts and significantly suppressed uterine glucosamine 6-phosphate synthase activity. There was no effect on implantation or the enzyme activity when Bc w...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:1993-04-01 00:00:00
abstract::Dianex, a polyherbal formulation intended to use for diabetic patients, has been screened for toxic effects. For acute toxicity studies, Dianex was administered orally in graded doses of 0.75-10 g/kg to the mice. For subacute toxicity studies, different doses of Dianex (1.0, 1.5 and 2.5 g/kg) were administered orally ...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:2003-04-01 00:00:00
abstract::Changes in biomass yield rates, cell membrane stability (CMS), malondialdehyde (MDA) content and in the levels of physiological stress markers such as proline and glycine betaine in two high yielding genotypes (S1 and ATP, salt tolerant and salt sensitive, respectively) of mulberry under NaCl salinity were studied. Bi...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:2000-02-01 00:00:00
abstract::Last instar larvae of S. mauritia treated topically on day 0, day 1, day 2 and day 3 with a daily (dose of 25 microg juvenile hormone analogue (JHA) moulted into supernumerary larvae. The imaginal discs of the supernumerary larvae especially those of mouthparts and thoracic appendages showed pupal characteristics. How...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:2003-02-01 00:00:00
abstract::Drought stress is one of the major factors affecting nitrogen fixation by legume-rhizobium symbiosis. Several mechanisms have been previously reported to be involved in the physiological response of symbiotic nitrogen fixation to drought stress, i.e. carbon shortage and nodule carbon metabolism, oxygen limitation, and...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章,评审
doi:
更新日期:2003-10-01 00:00:00
abstract::Effects of 1,1,1,-trichloro-2,2-bis (p-chlorophenyl) ethane (DDT) and lindane were studied on gamma glutamyl transpeptidase (GGT) activity in different tissues of the lymphoid system in rats. DDT (100 or 200 ppm) and lindane (30 or 80 ppm) exposure for 8 weeks suppressed the GGT activity in a dose dependent manner in ...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:1997-10-01 00:00:00
abstract::Intestinal epithelium secretes novel unilamellar membranes having characteristics similar to lung surfactants and thus has been named Surfactant-like particles (SLP). The chemical analysis of the membranes revealed cholesterol/phospholipid molar ratio of 0.68-0.78, which is much distinct from that of the underlying mi...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章,评审
doi:
更新日期:2006-07-01 00:00:00
abstract::Significant reduction (68.38%) in sheath blight disease of rice was noticed when foliar spray of a systemic fungicide, kitazin (480 micrograms mg-1), was applied twice at an interval of 2 days before inoculation. SDS-PAGE analysis of proteins of Rhizoctonia-infected rice leaf sheaths revealed the presence of 16 protei...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:1997-06-01 00:00:00
abstract::Dicarboxylic acids and a few amino acids were found to support mitochondrial phosphorylation in A. ceylanicum. Anaerobiasis markedly reduced this activity. Maximum effect was observed on succinate supported phosphorylation which in anaerobic atmosphere yielded only 2% ATP compared to that in the presence of air. Known...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:1990-06-01 00:00:00
abstract::While there is an emphasis on the early glycemic control for its long-term benefits in preventing microvascular complications of diabetes, the biochemical mechanisms responsible for the long-lasting effects are not clearly understood. Therefore the impact of early insulin (EI) versus late insulin (LI) treatment on dia...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:2013-01-01 00:00:00