Laser Doppler perfusion imaging of proximal interphalangeal joints in patients with rheumatoid arthritis.

Abstract:

OBJECTIVE:A non-invasive imaging technique (laser Doppler perfusion imaging-LDI) based on measurement of backscattered Doppler-broadened near infra-red laser radiation was used to provide two-dimensional images of perfusion over the proximal interphalangeal (PIP) joints of a group of normal subjects compared to a group of patients with rheumatoid arthritis (RA). RESULTS:Some PIP joints of the RA group showed areas of increased perfusion whereas normal subjects showed much less variation in perfusion between joints. These hyperaemic areas arose from the underlying joint, as scans taken with a less penetrating red laser did not show such areas. CONCLUSION:Apart from its obvious dermatological uses, LDI could be employed to image hyperaemia associated with a variety of inflammatory conditions affecting subcutaneous structures.

journal_name

Clin Exp Rheumatol

authors

Ferrell WR,Sturrock RD,Mallik AK,Abbot NC,Lockhart JC,Edmondson WD

subject

Has Abstract

pub_date

1996-11-01 00:00:00

pages

649-52

issue

6

eissn

0392-856X

issn

1593-098X

journal_volume

14

pub_type

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