Usefulness of a new rapid bedside troponin T assay in patients with chest pain.

Abstract:

:We evaluated the usefulness of a rapid, qualitative, bedside immunoassay for cardiac-specific troponin T in patients with chest pain. A concordant result between quantitative troponin T and qualitative troponin T assay was observed in 183 (96%) tests. The sensitivity of the rapid troponin T assay for detecting acute myocardial infarction increased significantly according to the number of hours elapsed after onset of chest pain from 17% for patients presenting within 4 h to 71% for patients presenting in the time interval of greater than 8 h from onset of chest pain (P < 0.001). Specificity ranged from 83 to 93% in the three time intervals evaluated. A concordant result between CK-MB-measurement and rapid troponin T assay was observed in 159 (83%) tests. In 14/191 tests a positive rapid troponin T and a negative CK-MB assay was observed. In 9/14 (64%) cases this result was true positive for the rapid troponin T assay and in 5/14 (36%) cases false negative. As sensitivity and specificity of the rapid troponin T assay are comparable with CK-MB measurements, rapid troponin T assay is a simple and useful laboratory tool for the bedside triage in patients with chest pain.

journal_name

Resuscitation

journal_title

Resuscitation

authors

Hirschl MM,Lechleitner P,Friedrich G,Sint G,Sterz F,Binder M,Dienstl F,Laggner AN

doi

10.1016/0300-9572(96)00969-0

subject

Has Abstract

pub_date

1996-10-01 00:00:00

pages

193-8

issue

3

eissn

0300-9572

issn

1873-1570

pii

0300957296009690

journal_volume

32

pub_type

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