Abstract:
:A light and electron microscopic study was performed to determine age changes in Meissner corpuscles. In forepaw digital pads of mice aged to their maximum life expectancy, corpuscles were found to increase in size and complexity until middle age, and then to become smaller, disorganized and lobulated with more advanced age. Nerve terminals at more advanced ages became attenuated with a loss of axonal processes, increased density of the axoplasm, and disordered arrangement of the organelles. Degeneration of axonal mitochondria accelerated with age. Lamellar cell processes investing the axons often become dense and attenuated with fewer plasmalemma-associated vesicles. Basal laminae remained where lamellar processes had disintegrated. Lipofuscin was seen in the lamellar cells only at extremely old age. Extracellular material composed of fine basal lamina substance and collagen fibrils increased remarkably with age. Increased growth and complexity of corpuscles until middle age perhaps compensated for age-associated loss of corpuscles and primary sensory neurons. Changes predominating at older ages are attributed to distal axonopathy and atrophy of the sensory neurons. The probable effect of these age changes on cutaneous sensitivity is considered in relation to current theory of mechanoelectric transduction.
journal_name
Microsc Res Techjournal_title
Microscopy research and techniqueauthors
Nava PB,Mathewson RCdoi
10.1002/(SICI)1097-0029(19960701)34:4<376::AID-JEMsubject
Has Abstractpub_date
1996-07-01 00:00:00pages
376-89issue
4eissn
1059-910Xissn
1097-0029pii
10.1002/(SICI)1097-0029(19960701)34:4<376::AID-JEMjournal_volume
34pub_type
杂志文章abstract::Contraction of muscular tissue requires the synchronized shortening of myofibers arrayed in complex geometrical patterns. Imaging such myofiber patterns with diffusion-weighted MRI reveals architectural ensembles that underlie force generation at the organ scale. Restricted proton diffusion is a stochastic process res...
journal_title:Microscopy research and technique
pub_type: 杂志文章,评审
doi:10.1002/jemt.22777
更新日期:2018-02-01 00:00:00
abstract::Neuropeptides are peptides with profound effects on the nervous system. The function of neuropeptides can be studied in detail in the stomatogastric nervous system (STNS). Neuropeptides are ubiquitously distributed in the STNS and it contains well-studied neural circuits that are strongly modulated by neuropeptides. T...
journal_title:Microscopy research and technique
pub_type: 杂志文章,评审
doi:10.1002/jemt.10269
更新日期:2003-02-15 00:00:00
abstract::The glycoconjugate pattern of developing ovarian follicles in wild and cultured Senegalese sole Solea senegalensis was investigated by means of lectin histochemistry. Ovaries from cultured fish contained oocytes up to the late vitellogenic stage, whereas they reached the hydration stage in wild specimens. The follicul...
journal_title:Microscopy research and technique
pub_type: 杂志文章
doi:10.1002/jemt.22040
更新日期:2012-08-01 00:00:00
abstract::The energy resolution of an energy dispersive spectrometer (EDS) equipped with an ultrathin window (UTW) and mounted at a high take-off angle (72 degrees) on a transmission electron microscope has been studied under a variety of operating conditions. The spectrometer resolution is close to that specified by the manufa...
journal_title:Microscopy research and technique
pub_type: 杂志文章
doi:10.1002/jemt.1070220208
更新日期:1992-07-01 00:00:00
abstract::Progressive multifocal leukoencephalopathy is an important viral opportunistic infection of oligodendrocytes leading to direct demyelination. Virus is likely disseminated to the brain via the blood. However, the timing of that dissemination with relationship to clinical disease is unknown. Important clues about viral ...
journal_title:Microscopy research and technique
pub_type: 杂志文章,评审
doi:10.1002/jemt.1070320405
更新日期:1995-11-01 00:00:00
abstract::This study follows the left ventricular (LV) hypertrophy in rats undergoing aerobic training alone (A), resistance training alone (R), or combined resistance and aerobic training (RA) (usually referred as concurrent training) program. A sedentary control group (C) was included. LV remodeling was evaluated using electr...
journal_title:Microscopy research and technique
pub_type: 杂志文章
doi:10.1002/jemt.22394
更新日期:2014-09-01 00:00:00
abstract::The ultrastructural characteristics of peptidergic peripheral contacts in the snail, Helix pomatia, were investigated, with special attention to the innervation of the heart, buccal mass, and salivary gland by Mytilus inhibitory peptide-immunoreactive neurons. Following the application of correlative light- and electr...
journal_title:Microscopy research and technique
pub_type: 杂志文章
doi:10.1002/1097-0029(20000615)49:6<534::AID-JEMT4>3.0
更新日期:2000-06-15 00:00:00
abstract::The intravacuolar network inside the parasitophorous vacuole of Toxoplasma gondii consists of an intricate system of membrane-limited tubules of uncertain role in parasite development. We propose that it is an important structural support to the maintenance of the parasites in the characteristic rosette arrangement of...
journal_title:Microscopy research and technique
pub_type: 杂志文章
doi:10.1002/jemt.20182
更新日期:2005-05-01 00:00:00
abstract::The implantation of breast prostheses for both aesthetic and reconstructive purposes has been growing exponentially in the last 20 years. Safety and prosthesis lifespan are majorly debated issues in relation to the correlated long-term complications. Mainly the periprosthetic capsule that develops around the implant i...
journal_title:Microscopy research and technique
pub_type: 杂志文章
doi:10.1002/jemt.23673
更新日期:2020-12-10 00:00:00
abstract::The opossum Monodelphis domestica presents movement of the temporomandibular joint (TMJ) reflecting adaptation to eating habits similar to movement in humans, but the structure of the TMJ is not yet known. Thus, nine young M. domestica, of both sexes were weighed, anesthetized with xylazine (10 mg kg(-1) ), and ketami...
journal_title:Microscopy research and technique
pub_type: 杂志文章
doi:10.1002/jemt.22702
更新日期:2016-09-01 00:00:00
abstract::This paper describes four investigations of the olfactory mucosa of the brown trout: 1) the ultrastructure of the olfactory mucosa as revealed by scanning (SEM), conventional transmission (TEM), and high voltage (HVEM) electron microscopy; 2) light and electron-microscopic investigations of retrograde transport of the...
journal_title:Microscopy research and technique
pub_type: 杂志文章
doi:10.1002/jemt.1070230104
更新日期:1992-10-01 00:00:00
abstract::Several models for preparing and isolating human and animal gallbladder epithelial cells, including low-grade gallbladder carcinoma cells, as well as proposed systems for culturing these isolated epithelial cells are reviewed here. Several reports concerning tissue culture of the gallbladder are also reviewed. The cel...
journal_title:Microscopy research and technique
pub_type: 杂志文章,评审
doi:10.1002/(SICI)1097-0029(19971001)39:1<71::AID-JEMT
更新日期:1997-10-01 00:00:00
abstract::E-cadherin and its associated cytoplasmic proteins alpha-, beta-, and gamma-catenin, play a crucial role in epithelial cell-cell adhesion and in the maintenance of tissue architecture. Perturbation in the expression or function of any of these molecules results in loss of intercellular adhesion, with possible conseque...
journal_title:Microscopy research and technique
pub_type: 杂志文章,评审
doi:10.1002/(SICI)1097-0029(19981101)43:3<224::AID-JEM
更新日期:1998-11-01 00:00:00
abstract::We present de novo studies and review published efforts from our laboratory, spanning 12 years (from 1988 to 2000), where we have used ultrastructural approaches to study the functional anatomy of the microvasculature in man and animals in health and disease. These efforts have defined a new endothelial cell organelle...
journal_title:Microscopy research and technique
pub_type: 杂志文章,评审
doi:10.1002/jemt.10087
更新日期:2002-06-01 00:00:00
abstract::Leishmaniasis is a worldwide public health problem and vector-borne disease. It is caused by a diverse group of protozoan parasites that belong to the genus Leishmania and transmitted to humans through a bite of an infected female sand fly. Leishmaniasis has attained epidemic proportion in Khyber Pakhtunkhwa and raise...
journal_title:Microscopy research and technique
pub_type: 杂志文章
doi:10.1002/jemt.23462
更新日期:2020-07-01 00:00:00
abstract::The tip is one of the critical factors to improve the efficiency in picking up individual DNA molecules from solid substrates based on atomic force microscope (AFM) nanomanipulation. We found that wearing AFM tips on certain solid substrates in advance to nanomanipulation operation would largely improve the pickup eff...
journal_title:Microscopy research and technique
pub_type: 杂志文章
doi:10.1002/jemt.21104
更新日期:2012-05-01 00:00:00
abstract::Virus particles and viral inclusions were detected by transmission electron microscopy examination of sections of the seminal vesicles and mucus gland of asymptomatic young drones from colonies of Apis mellifera lightly infested by Varroa mite. In the mucus gland the infection was found in the muscular sheath and epit...
journal_title:Microscopy research and technique
pub_type: 杂志文章
doi:10.1002/jemt.22024
更新日期:2012-07-01 00:00:00
abstract::In the present work, we propose the use of the Laser Scanning Confocal Microscopy (LSCM) to determine the effect of water repellents on rock's pore-network configuration and interconnection. The rocks studied are sandstones of Miocene age, a building material that is commonly found in the architectural heritage of Tun...
journal_title:Microscopy research and technique
pub_type: 杂志文章
doi:10.1002/jemt.20624
更新日期:2008-11-01 00:00:00
abstract::The region-specific angioarchitecture of the bovine pododerma was examined using systematic scanning electron microscopy of micro-corrosion casts of juvenile and adult bovine claws. Particular emphasis was laid on the demonstration of specialised vascular structures such as arteriovenous anastomoses. Comparing the res...
journal_title:Microscopy research and technique
pub_type: 杂志文章
doi:10.1002/jemt.1150
更新日期:2001-09-15 00:00:00
abstract::A photochemical reaction was used to produce focal microcirculation disorders in the guinea pig cochlea. Temporal bones were removed at various intervals between 5 minutes and 1 month after infusion of rose bengal (RB) and illumination. Infused but unilluminated contralateral cochleae served as controls. Dissected coc...
journal_title:Microscopy research and technique
pub_type: 杂志文章
doi:10.1002/(SICI)1097-0029(19980515)41:4<323::AID-JEM
更新日期:1998-05-15 00:00:00
abstract::The cyclic fluctuations in circulating levels of 17 beta-estradiol and progesterone that occur during the menstrual or estrous cycle are responsible for dramatic, cyclic changes in the epithelial lining and secretory status of the mammalian oviduct. The timely transition in the synthesis and release of oviduct protein...
journal_title:Microscopy research and technique
pub_type: 杂志文章,评审
doi:10.1002/jemt.1070310606
更新日期:1995-08-15 00:00:00
abstract::The autonomic neuromuscular junction at a varicosity in the vas deferens is defined by the localization of the vesicle-associated protein syntaxin in high concentrations in the axolemma and a high density of P2x1 receptors in a cluster beneath the varicosity. Calcium fluxes have been observed in all individual varicos...
journal_title:Microscopy research and technique
pub_type: 杂志文章,评审
doi:10.1002/(SICI)1097-0029(19980915)42:6<433::AID-JEM
更新日期:1998-09-15 00:00:00
abstract::Antlion (Myrmeleon sagax) larvae live in sandy soil and possess the ability to enter soil quickly. In this article, the hierarchical structure of the nonsmooth surface of antlion larvae was obtained using a scanning electron microscope (SEM). Based on the results, a bionic nonsmooth structure model was established to ...
journal_title:Microscopy research and technique
pub_type: 杂志文章
doi:10.1002/jemt.23419
更新日期:2020-04-01 00:00:00
abstract::Studies on embryonic development in vitro as well as observations in vivo, suggested that two aspects of oviduct physiology are important for early development. On one side has to be considered the oviduct "environment": temperature, pH, osmotic pressure, nutrients, oxygen tension, free radical scavengers, etc. On the...
journal_title:Microscopy research and technique
pub_type: 杂志文章,评审
doi:10.1002/jemt.1070320102
更新日期:1995-09-01 00:00:00
abstract::Neurons begin to polarize when one of the neurites becomes the axon. Hippocampal neurons in cell culture have a sharp transition between their unpolarized and polarized stage revealed by the rapid growth of the future axon. Recent progress shows that both a cytoplasmic membrane flow and actin dynamics govern axon form...
journal_title:Microscopy research and technique
pub_type: 杂志文章,评审
doi:10.1002/(SICI)1097-0029(20000101)48:1<3::AID-JEMT2
更新日期:2000-01-01 00:00:00
abstract::An overview of the morphological correlates of mammalian epidermal lipids and the cutaneous permeability barrier is provided. The following features are discussed: 1) ultrastructural characterization of the progressive lipid alterations accompanying normal stratum corneum (SC) formation; 2) effects of drugs/inhibitors...
journal_title:Microscopy research and technique
pub_type: 杂志文章,评审
doi:10.1002/(SICI)1097-0029(19970501)37:3<180::AID-JEM
更新日期:1997-05-01 00:00:00
abstract::Oligodendrocytes (OL) play a significant physiological role in the central nervous system by creating the myelin sheath that allows for the efficient conduction of nerve impulses. Therefore, it is important to understand which signalling cascades define the proliferation, differentiation, survival, and myelin formatio...
journal_title:Microscopy research and technique
pub_type: 杂志文章,评审
doi:10.1002/jemt.1052
更新日期:2001-03-15 00:00:00
abstract::In this paper, an application of contact microradiography with soft X-rays for detecting the uptake site of heavy metal in the whole plant leaves is investigated. The X-ray source is a laser-plasma one based on an Nd:glass laser. The soft X-ray radiation emitted from the plasma laser targets of magnesium, iron, and co...
journal_title:Microscopy research and technique
pub_type: 杂志文章
doi:10.1002/jemt.20350
更新日期:2006-08-01 00:00:00
abstract::Epidemiologic studies have associated cardiovascular morbidity and mortality with ambient particulate air pollution. Particles smaller than 100 nm in diameter (ultrafine particles) are present in the urban atmosphere in very high numbers yet at very low mass concentration. Organs beyond the lungs are considered as tar...
journal_title:Microscopy research and technique
pub_type: 杂志文章
doi:10.1002/jemt.20044
更新日期:2004-04-01 00:00:00
abstract::To investigate intrinsic physicochemical properties and interactions of three different calcium hydroxide-based medications via means of different analytical methods. Two-commercial premixed medications: TempCanal(TCmx) and ProCalR(PCmx) and powder-form ProCal(PCpw) with glycerin were used. Vibrational modes were anal...
journal_title:Microscopy research and technique
pub_type: 杂志文章
doi:10.1002/jemt.23600
更新日期:2020-09-21 00:00:00