Abstract:
:The lignan 8,8'-bis-(methylenedioxy)cinnamic acid (BMDCA) is a powerful competitive inhibitor (K1 = 2.0 microM) of the lignin peroxidase (LiP) from Phanerochaete chrysosporium and of the extracellular peroxidase of Phlebia radiata (I0.5 = 10 microM). BMDCA derivatives with the same double bond system also inhibited these enzymes to some extent. If the double bonds were hydrogenated, the inhibitory effect was lost. HRP-VIII and HRP-XI were slightly inhibited by BMDCA (I0.5 > 50 microM) and two plant peroxidases described as efficient lignan synthesizers were unaffected. Liquid cultures of P chrysosporium did not discolour the dve Poly R478 when 250 microM of BMDCA was present.
journal_name
Biochimiejournal_title
Biochimieauthors
Frías I,Trujillo JM,Romero J,Hernandez J,Pérez JAdoi
10.1016/0300-9084(96)88186-7subject
Has Abstractpub_date
1995-01-01 00:00:00pages
707-12issue
9eissn
0300-9084issn
1638-6183pii
0300-9084(96)88186-7journal_volume
77pub_type
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