Isolation and characterization of porcine cationic eosinophil granule proteins.

abstract：:A high-dose, accelerated escalation schedule during subcutaneous allergen-specific immunotherapy (AIT) is safe and well-tolerated in adults. However, there are no data in children and adolescents. The aim of the present trial was to assess safety and tolerability of an accelerated dose escalation schedule of an AIT wi...

journal_title：International archives of allergy and immunology

authors： Bovermann X,Ricklefs I,Vogelberg C,Klimek L,Kopp MV

更新日期：2021-01-27 00:00:00

abstract：BACKGROUND:Modulating early immune response by application of bacteria and their by-products has been suggested as a preventive strategy against the development of allergic diseases. In light of this, the aim of the study was to test the effects of oral administration of bacterial lysates (BL) in a rat model of food al...

journal_title：International archives of allergy and immunology

authors： Ahrens B,Quarcoo D,Buhner S,Matricardi PM,Hamelmann E

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:Penicillium chrysogenum (Penicillium notatum) is a prevalent airborne Penicillium species. A 34-kD major IgE-reacting component from P. chrysogenum has been identified as an alkaline serine protease (Pen ch 13, also known as Pen n 13 before) by immunoblot and N-terminal amino acid sequence analysis. METHODS...

journal_title：International archives of allergy and immunology

authors： Chou H,Lai HY,Tam MF,Chou MY,Wang SR,Han SH,Shen HD

更新日期：2002-01-01 00:00:00

abstract：BACKGROUND:Previous studies have indicated that colitis increases intestinal permeability to food antigens. This condition also generates an immunoreactive milieu in the gut, which may exacerbate or counteract allergy reactions. This, along with the fact that both colitis and allergy are being codiagnosed more frequent...

journal_title：International archives of allergy and immunology

authors： Cueto-Sola M,Bailon E,Utrilla P,Rodríguez-Ruiz J,Garrido-Mesa N,Zarzuelo A,Xaus J,Gálvez J,Comalada M

更新日期：2013-01-01 00:00:00

abstract：:Monocytes and lymphocytes from human blood contain 0.043 +/- 0.007 and 0.053 +/- 0.014 pg histamine/cell, respectively, which can be released by a number of stimulants (A 23187, C5a, substance P, specific allergen). The release process takes 60-120 min to reach its end point, in contrast to tissue mast cells which com...

journal_title：International archives of allergy and immunology

authors： Schmutzler W,Bolsmann K,Zwadlo-Klarwasser G

更新日期：1995-05-01 00:00:00

abstract：:In murines, interleukins (IL) 3, 4, 9, and 10, nerve growth factor, and stem cell factor induce or promote growth and differentiation of mast cells (MC). Increased stimulation and synergy was observed when combinations of cytokines were used. In man, no growth factor for human MCs had been identified until recently, w...

journal_title：International archives of allergy and immunology

authors： Sillaber C,Sperr WR,Agis H,Spanblöchl E,Lechner K,Valent P

更新日期：1994-11-01 00:00:00

abstract：:HIV-1 RNA has become the standard for monitoring antiretroviral therapies. Dogma predicts, however, that a viral protein like p24 should be at least as good a marker of HIV disease activity, provided that it is measured with sufficient sensitivity and accuracy. Simple modifications including use of a more efficient vi...

journal_title：International archives of allergy and immunology

authors： Schüpbach J

更新日期：2003-11-01 00:00:00

abstract：INTRODUCTION:The aim of this study was to evaluate the effectiveness of specific immunotherapy (SIT) management with allergoids in children with allergic asthma by monitoring changes in clinical parameters and inflammatory markers in exhaled breath. METHODS:The study population included 43 patients (24 males) of 6-14 ...

journal_title：International archives of allergy and immunology

authors： Lozano J,Cruz MJ,Piquer M,Giner MT,Plaza AM

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:The cytokine transforming growth factor-beta(TGF-beta) has important regulatory roles in the immune system. To investigate the role of intact TGF-beta signaling during the contact hypersensitivity (CHS) response to a respiratory allergen, we exposed Smad3-/- mice to topical trimellitic anhydride (TMA). METH...

journal_title：International archives of allergy and immunology

authors： Anthoni M,Fyhrquist N,Lehtimäki S,Alenius H,Wolff H,Lauerma A

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:Despite parallel increases in asthma and obesity prevalence, there is little data on obesity as a risk factor for atopy. The latter is an important phenotype in asthmatic patients. This study investigates the association between asthma traits, atopy and obesity-related markers in Chinese adolescents. METHOD...

journal_title：International archives of allergy and immunology

authors： Leung TF,Kong AP,Chan IH,Choi KC,Ho CS,Chan MH,So WY,Lam CW,Wong GW,Chan JC

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND:Mountain cedar (Juniperus ashei) pollen commonly causes a winter time allergic rhinitis in the central USA. Jun a 1 is the dominant allergenic protein, but biologically active recombinant Jun a 1 has not been successfully expressed, despite numerous attempts with several expression systems. METHOD:Jun a 1 c...

journal_title：International archives of allergy and immunology

authors： Liu Z,Bhattacharyya S,Ning B,Midoro-Horiuti T,Czerwinski EW,Goldblum RM,Mort A,Kearney CM

更新日期：2010-01-01 00:00:00

abstract：:The prevalence of IgE myeloma is 0.01% in all plasmocytomas. Although signs and symptoms are similar, it is generally accepted that IgE myeloma has a more malignant clinical course than other forms of plasmocytoma with monoclonal gammopathy. The disease has widely variable presentation. Most of the reported cases were...

journal_title：International archives of allergy and immunology

authors： Jako JM,Gesztesi T,Kaszas I

更新日期：1997-04-01 00:00:00

abstract：BACKGROUND:The prevalence of allergic rhinitis (AR) is increasing rapidly in Central China. The skin prick test (SPT) is the standard tool with which to determine the allergen sensitization status in AR patients. Changes in allergen sensitization patterns have been observed within countries and regions due to geographi...

journal_title：International archives of allergy and immunology

authors： Wang J,Wu Y,Li J,Huang X,Zhu R

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:Dendritic cells (DC) play a decisive role in the induction of allergen-induced Th1 and Th2 responses. Since the induction of allergen-specific Th1 responses has shown to inhibit allergen-induced Th2-type inflammation, in this study we investigated whether manipulated myeloid-derived DC pulsed with the specif...

journal_title：International archives of allergy and immunology

authors： Trujillo-Vargas CM,Ramirez-Pineda JR,Palmetshofer A,Grunewald S,Moll H,Berberich C,Erb KJ

更新日期：2005-07-01 00:00:00

abstract：BACKGROUND:DNA immunization and protein immunization with CpG motifs as adjuvants represent promising approaches in allergen-specific immunotherapy. OBJECTIVE:We investigated the effect of coinjection or prepriming with CpG-ODN on Th2-type responses induced by gene gun and protein immunization. METHODS:BALB/c mice we...

journal_title：International archives of allergy and immunology

authors： Hochreiter R,Hartl A,Freund J,Valenta R,Ferreira F,Thalhamer J

更新日期：2001-01-01 00:00:00

abstract：:Mercuric chloride (HgCl(2)) has been proposed to be a mitogen for human blood lymphocytes in vitro. In our previous study, we demonstrated that HgCl(2) preferentially stimulates the CD4+ T cell subset to blast transformation and DNA synthesis and that the reaction is dependent on CD14+ accessory cells. In order to cha...

journal_title：International archives of allergy and immunology

authors： Loftenius A,Ekstrand J,Möller E

更新日期：1999-09-01 00:00:00

abstract：BACKGROUND:It is not known why some foods sensitizing via the gastrointestinal tract are prevalent allergenic foods and others are not. Eating habits, processing, and the food matrix have been suggested to influence the allergenicity of a given food. Factors related to protein structure, such as stability to digestion,...

journal_title：International archives of allergy and immunology

authors： Kroghsbo S,Bøgh KL,Rigby NM,Mills EN,Rogers A,Madsen CB

更新日期：2011-01-01 00:00:00

abstract：:Human foamy virus (HFV) is a recently characterized member of the retrovirus subfamily Spumaretrovirinae. HFV has a complex structure: it encodes the classical three retroviral structural genes gag, pol and env, but also possesses additional regulatory, so-called bel sequences. Foamy viruses have been discussed occasi...

journal_title：International archives of allergy and immunology

authors： Wick G,Grubeck-Loebenstein B,Trieb K,Kalischnig G,Aguzzi A

更新日期：1992-01-01 00:00:00

abstract：:In recent years, the Th1/Th2 concept has become of prime importance in the understanding of heterogeneous responses of the immune system and implications thereof for infectious and autoimmune diseases. Originally established on the basis of different cytokines produced by T cell clones, it is now known that the Th1/Th...

journal_title：International archives of allergy and immunology

authors： Lohoff M,Gessner A,Bogdan C,Röllinghoff M

更新日期：1998-03-01 00:00:00

abstract：:Antiphospholipid antibody syndrome (APS) is characterized by autoantibodies against negatively charged phospholipids in the serum, and clinically by multiple thromboses, thrombocytopenia, and recurrent fetal loss. The mechanism(s) by which the antibodies cause the clinical picture are not clear. We review the possible...

journal_title：International archives of allergy and immunology

authors： Aron AL,Gharavi AE,Shoenfeld Y

更新日期：1995-01-01 00:00:00

abstract：BACKGROUND:It has been shown that antigen presentation by resting B cells can induce tolerance to intravenously administered protein antigens, but the role of resting B cells in the induction of oral tolerance is unclear. METHODS:Mice continuously treated since birth with rabbit anti-mouse IgM serum for 5 weeks were d...

journal_title：International archives of allergy and immunology

authors： Peng HJ,Chang ZN,Kuo SW,Lee CC,Tzau YY

更新日期：2000-07-01 00:00:00

abstract：BACKGROUND:Severe asthma is a heterogeneous disease, which is characterized by airway damage and remodeling. All triggers of asthma, such as allergens, bacteria, viruses, and pollutants, interact with the airway epithelial cells, which drive the airway inflammatory response through the release of cytokines, particularl...

journal_title：International archives of allergy and immunology

authors： Boita M,Heffler E,Omedè P,Bellocchia M,Bussolino C,Solidoro P,Giorgis V,Guerrera F,Riva G,Brussino L,Bucca C,Rolla G

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:Cytosolic phospholipase A2 (cPLA2) plays a key role in the development of late-phase anaphylaxis. L-Glutamine (Gln), a nonessential amino acid, has anti-inflammatory activity via inhibiting cPLA2. METHODS:We used a penicillin-induced murine model of anaphylaxis, and late-phase anaphylaxis was quantified by ...

journal_title：International archives of allergy and immunology

authors： Kim HK,Song CH,Bae YS,Im SY,Lee HK

更新日期：2016-01-01 00:00:00

abstract：:We studied the binding activities of IgE, IgG and IgA antibodies in patients with allergy to hen's egg white against two different ovalbumin (OVA) preparations, which were physically or chemically denatured OVA and enzyme-digested OVA fragments. The binding activities of IgE antibodies to these OVA preparations with t...

journal_title：International archives of allergy and immunology

authors： Honma K,Kohno Y,Saito K,Shimojo N,Tsunoo H,Niimi H

更新日期：1994-01-01 00:00:00

abstract：:The antigenic and allergenic characteristics of three bovine epithelial extracts, dander, skin scrapings and whole skin, were compared using IgE-ELISA inhibition and SDS-PAGE with immunoblotting. Cow dander extract was shown to contain more allergenic activity than skin scrapings or whole skin extracts which were need...

journal_title：International archives of allergy and immunology

authors： Ylönen J,Mäntyjärvi R,Taivainen A,Virtanen T

更新日期：1992-01-01 00:00:00

abstract：:Homogenates of bovine iris were fractionated by gel filtration chromatography, and the column-eluted proteins were probed with pooled sera obtained from patients with pauciarticular juvenile rheumatoid arthritis (JRA). The serum pool prepared from patients with pauciarticular JRA and a history of anterior uveitis, but...

journal_title：International archives of allergy and immunology

authors： Hunt DW,Petty RE,Millar F

更新日期：1993-01-01 00:00:00

abstract：:We carried out a cross-sectional chronobiological investigation on blood histamine, thyroid histamine and thyroid mast cell number in Wistar rats. Daily, blood histamine varied from 0.38 +/- 0.01 (12.00 h) to 0.60 +/- 0.01 mg/g wet weight (20.00 h) and thyroid histamine from 21.2 +/- 1.19 (04.00 h) to 38.3 +/- 1.54 mg...

journal_title：International archives of allergy and immunology

authors： Catini C,Miliani A,Macchi C

更新日期：1994-12-01 00:00:00

abstract：:The aim of this study was to assess the relevance of immunoinflammatory markers on the response to short acting beta(2)-agonist in acute asthma exacerbation. Thus, we measured serum eosinophil cationic protein (ECP) levels and sIL-2R at acute exacerbation in 52 adult patients with atopic asthma, and assessed forced ex...

journal_title：International archives of allergy and immunology

authors： Di Lorenzo G,Pacor ML,Morici G,Drago A,Esposito-Pellitteri M,Candore G,Lo Bianco C,Caruso C

更新日期：2002-04-01 00:00:00

abstract：BACKGROUND:Intestinal intraepithelial lymphocytes (iIELs) play an important role in intestinal innate immunity and oral immune tolerance. To compare the differences in gene expression between murine iIELs and splenic T lymphocytes, we established the cDNA subtractive library of iIELs and analyzed the iIELs special gene...

journal_title：International archives of allergy and immunology

authors： Ma C,Xu C,Duan L,He W

更新日期：2006-01-01 00:00:00

abstract：:The peripheral blood mononuclear cells (PBMC) from humans allergic to grass pollens (GR+ subjects) show strong in vitro proliferative responses to purified allergens from Lolium perenne pollen Lol p 1, and to a lesser extent to Lol p 2 and Lol p 3. By contrast, PBMC from grass allergic patients undergoing immunotherap...

journal_title：International archives of allergy and immunology

authors： Baskar S,Hamilton RG,Norman PS,Ansari AA

更新日期：1997-02-01 00:00:00