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Synthesis and structure-activity relationship of (lactamylvinyl)cephalosporins exhibiting activity against staphylococci, pneumococci, and enterococci.

Abstract：

:The synthesis and structure-activity relationships of a new class of vinylcephalosporins substituted with a lactamyl residue are described. These compounds show excellent activity against enterococci and retain the broad spectrum activity of third-generation cephalosporins such as ceftriaxone.

journal_name

J Med Chem

journal_title

Journal of medicinal chemistry

authors

Heinze-Krauss I,Angehrn P,Guerry P,Hebeisen P,Hubschwerlen C,Kompis I,Page MG,Richter HG,Runtz V,Stalder H,Weiss U,Wei CC

doi

10.1021/jm950886v

subject

Has Abstract

pub_date

1996-04-26 00:00:00

pages

1864-71

issue

9

eissn

0022-2623

issn

1520-4804

pii

jm950886v

journal_volume

39

pub_type

杂志文章

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