Evaluation of a dentin barrier test by cyctotoxicity testing of various dental cements.


:In this study, cell reaction after exposure to several dental cements was determined using a dentin barrier test device. The reaction of mouse fibroblasts grown on the "pulpal" side of a bovine dentin disk was determined after exposure to dental cements applied on the "cavity" side of the disk. For pretreatment, dentin disks (500-micrometer-thick) were etched on one side and either sterilized by autoclaving or disinfected with ethanol. It was found for both pretreatment groups that zinc phosphate cement was less toxic than the conventional glass ionomer cements. A light-cured glass ionomer cement and zinc oxide-eugenol were the most toxic materials tested. Disinfecting the dentin slices instead of autoclaving reduced the toxicity of the phosphate cement and the glass ionomer cements tendentiously. Because the strong cytotoxic reaction evoked by zinc oxide-eugenol and by the glass ionomer cements is in contrast to in vivo findings, further improvements of the dentin barrier test device will be necessary.


J Endod


Journal of endodontics


Schmalz G,Schweikl H,Esch J,Hiller KA




Has Abstract


1996-03-01 00:00:00














  • Dynamic Torsional and Cyclic Fracture Behavior of ProFile Rotary Instruments at Continuous or Reciprocating Rotation as Visualized with High-speed Digital Video Imaging.

    abstract:INTRODUCTION:This study examined the dynamic fracture behavior of nickel-titanium rotary instruments in torsional or cyclic loading at continuous or reciprocating rotation by means of high-speed digital video imaging. METHODS:The ProFile instruments (size 30, 0.06 taper; Dentsply Maillefer, Ballaigues, Switzerland) we...

    journal_title:Journal of endodontics

    pub_type: 杂志文章


    authors: Tokita D,Ebihara A,Miyara K,Okiji T

    更新日期:2017-08-01 00:00:00

  • Indirect pulp capping and primary teeth: is the primary tooth pulpotomy out of date?

    abstract::Formocresol pulpotomy (FP) in the United States is most frequently used to treat asymptomatic caries near the pulp in primary teeth. Indirect pulp therapy (IPT) is also indicated and has a significantly higher long-term success. Pulpotomy is thought to be indicated for primary teeth with carious pulp exposures, but re...

    journal_title:Journal of endodontics

    pub_type: 杂志文章,评审


    authors: Coll JA

    更新日期:2008-07-01 00:00:00

  • Long-term prognosis of endodontically treated teeth: a retrospective analysis of preoperative factors in molars.

    abstract:INTRODUCTION:Long-term predictability of restored endodontically treated teeth is important for the decision of tooth retention versus extraction and implant placement. The purpose of this study was to validate the hypothesis that preoperative factors can predict the long-term prognosis of molars requiring endodontic a...

    journal_title:Journal of endodontics

    pub_type: 杂志文章


    authors: Setzer FC,Boyer KR,Jeppson JR,Karabucak B,Kim S

    更新日期:2011-01-01 00:00:00

  • Evaluation of the Raypex 5 and the Mini Apex Locator: an in vivo study.

    abstract:INTRODUCTION:The purpose of this study was to compare the accuracy in vivo of 2 electronic apex locators (EALs), the Raypex 5 and the Mini Apex Locator. METHODS:The working length (WL) was determined electronically for 40 human root canals by using a K-file and 1 of the 2 EALs. The files were fixed at the WL, and the ...

    journal_title:Journal of endodontics

    pub_type: 杂志文章,随机对照试验


    authors: Stöber EK,de Ribot J,Mercadé M,Vera J,Bueno R,Roig M,Duran-Sindreu F

    更新日期:2011-10-01 00:00:00

  • Postdebridement retention of endodontic reagents: a quantitative measurement with radioactive isotope.

    abstract::Forty freshly extracted human teeth were biomechanically prepared for endodontic obturation using a radioisotopically labeled EDTA-urea peroxide-Carbowax compound. The amount of radiolabeled mixture remaining in the canals after through cleansing was about 3.8% of that originally applied. The amount of residue did not...

    journal_title:Journal of endodontics

    pub_type: 杂志文章


    authors: Zurbriggen T,del Rio CE,Brady JM

    更新日期:1975-09-01 00:00:00

  • New core and sealer materials for root canal obturation and retrofilling.

    abstract::A new endodontic obturation and retrofilling material has been invented to satisfy Grossman's requirements for an ideal material. Methylene blue dye leakage studies were carried out to compare the new material with conventional products, for both obturation and retrofilling. The experimental material when used in root...

    journal_title:Journal of endodontics

    pub_type: 杂志文章


    authors: Reeh ES,Combe EC

    更新日期:2002-07-01 00:00:00

  • Influence of single-file endodontics on apical transportation in curved root canals: an ex vivo micro-computed tomographic study.

    abstract:INTRODUCTION:More information regarding the ability of single files to maintain the original canal position is required before adopting a single-file approach to cleaning and shaping. This study compares apical transportation in curved root canals when instrumenting with a single WaveOne (WO) file (Dentsply Tulsa Denta...

    journal_title:Journal of endodontics

    pub_type: 杂志文章


    authors: Junaid A,Freire LG,da Silveira Bueno CE,Mello I,Cunha RS

    更新日期:2014-05-01 00:00:00

  • A Retrospective Brazilian Multicenter Study of Biopsies at the Periapical Area: Identification of Cases of Nonendodontic Periapical Lesions.

    abstract:INTRODUCTION:The purpose of this study was to analyze the features of lesions obtained from biopsies at the periapical area of teeth with a radiographic or clinical initial diagnosis of apical periodontitis. METHODS:A retrospective study was conducted on biopsies obtained from 1953-2018 at 3 Brazilian oral and maxillo...

    journal_title:Journal of endodontics

    pub_type: 杂志文章,多中心研究


    authors: Vieira CC,Pappen FG,Kirschnick LB,Cademartori MG,Nóbrega KHS,do Couto AM,Schuch LF,Melo LA,Dos Santos JN,de Aguiar MCF,Vasconcelos ACU

    更新日期:2020-04-01 00:00:00

  • Outcomes of nonsurgical retreatment and endodontic surgery: a systematic review.

    abstract:INTRODUCTION:The purpose of this systematic review was to compare the clinical and radiographic outcomes of nonsurgical retreatment with those of endodontic surgery to determine which modality offers more favorable outcomes. METHODS:The study began with targeted electronic searches of MEDLINE, PubMed, and Cochrane dat...

    journal_title:Journal of endodontics

    pub_type: 杂志文章,meta分析,评审


    authors: Torabinejad M,Corr R,Handysides R,Shabahang S

    更新日期:2009-07-01 00:00:00

  • Hepatocyte growth factor exerts promoting functions on murine dental papilla cells.

    abstract::Hepatocyte growth factor (HGF) is a potent mitogenic and angiogenic factor involved in the development of many tissues including the teeth. We previously reported that dental pulp cells express the HGF receptor c-met and that HGF can enhance cell proliferation and differentiation. The purpose of this study was to dete...

    journal_title:Journal of endodontics

    pub_type: 杂志文章


    authors: Li R,Peng L,Ren L,Tan H,Ye L

    更新日期:2009-03-01 00:00:00

  • Roentgenographic in vitro investigation of frequency and location of curvatures in human maxillary premolars.

    abstract::The aim of this study was to determine the location of the root canal curvature and measure the distance from the CEJ to the first curvature using in vitro methods. Extracted maxillary premolars (n = 358) were fixed and digitally radiographed using the parallel technique. Excluded from further analysis were teeth with...

    journal_title:Journal of endodontics

    pub_type: 杂志文章


    authors: Willershausen B,Tekyatan H,Kasaj A,Marroquín BB

    更新日期:2006-04-01 00:00:00

  • A comparison of canal centering ability of four instrumentation techniques.

    abstract::The purpose of this study was to compare three engine driven (nickel-titanium) NiTi instrument systems with hand files for their effect on canal transportation. Mesial roots of mature lower first molars with separate canals were paired on the basis of curvature and morphology. Canal lengths were standardized to 11 mm ...

    journal_title:Journal of endodontics

    pub_type: 杂志文章


    authors: Short JA,Morgan LA,Baumgartner JC

    更新日期:1997-08-01 00:00:00

  • Regional push-out bond strength and coronal microleakage of Resilon after different light-curing methods.

    abstract::The purpose of this study was to assess the push-out bond strength and coronal microleakage of the Epiphany (Pentron Clinical Technologies, Wallingford, CT) + Resilon (Resilon Research LLC, Madison, CT) obturation system with respect to different photoactivation methods used. Roots of human maxillary central incisors ...

    journal_title:Journal of endodontics

    pub_type: 杂志文章


    authors: Nagas E,Cehreli ZC,Durmaz V,Vallittu PK,Lassila LV

    更新日期:2007-12-01 00:00:00

  • In the Dental Implant Era, Why Do We Still Bother Saving Teeth?

    abstract::Teeth are vital sensory organs that contribute to our daily activities of living. Unfortunately, teeth can be lost for several reasons including trauma, caries, and periodontal disease. Although dental trauma injuries and caries are more frequently encountered in a younger population, tooth loss because of periodontal...

    journal_title:Journal of endodontics

    pub_type: 杂志文章


    authors: Clark D,Levin L

    更新日期:2019-12-01 00:00:00

  • Fracture strength of roots instrumented with self-adjusting file and the ProTaper rotary systems.

    abstract:INTRODUCTION:The purpose of this study was to evaluate the fracture strength of roots instrumented with the Self-Adjusting File (SAF; ReDent-Nova, Ra'anana, Israel) and the ProTaper system (Dentsply Maillefer, Ballaigues, Switzerland) and filled with the cold lateral compaction technique. METHODS:In total, 50 mandibul...

    journal_title:Journal of endodontics

    pub_type: 杂志文章


    authors: Capar ID,Altunsoy M,Arslan H,Ertas H,Aydinbelge HA

    更新日期:2014-04-01 00:00:00

  • Pain reduction in untreated irreversible pulpitis using an intraosseous injection of Depo-Medrol.

    abstract::The purpose of this prospective, double-blind, randomized study was to evaluate pain reduction using an intraosseous injection of slow-releasing methylprednisolone in teeth with irreversible pulpitis. Forty subjects presenting for emergency treatment completed the study. Each subject had a tooth with a clinical diagno...

    journal_title:Journal of endodontics

    pub_type: 临床试验,杂志文章,随机对照试验


    authors: Gallatin E,Reader A,Nist R,Beck M

    更新日期:2000-11-01 00:00:00

  • Prevalence and Characteristics of the Maxillary C-shaped Molar.

    abstract:INTRODUCTION:The anatomy of the maxillary C-shaped molar has been the subject of several case reports although no true prevalence research has ever been conducted. The aim of this observational study was to evaluate and characterize the incidence of these morphologies using cone-beam computed tomographic (CBCT) technol...

    journal_title:Journal of endodontics

    pub_type: 杂志文章


    authors: Martins JN,Mata A,Marques D,Anderson C,Caramês J

    更新日期:2016-03-01 00:00:00

  • Effect of Liquid Platelet-rich Fibrin and Platelet-rich Plasma on the Regenerative Potential of Dental Pulp Cells Cultured under Inflammatory Conditions: A Comparative Analysis.

    abstract:INTRODUCTION:Platelet-rich plasma (PRP) has been widely used in regenerative dentistry for over 2 decades. Nevertheless, previous studies have shown that its growth factor content is released over a short time period, and the application of anticoagulants limits its regenerative potential. Therefore, a second-generatio...

    journal_title:Journal of endodontics

    pub_type: 杂志文章


    authors: Chai J,Jin R,Yuan G,Kanter V,Miron RJ,Zhang Y

    更新日期:2019-08-01 00:00:00

  • The use of guided tissue regeneration techniques among endodontists: a web-based survey.

    abstract:INTRODUCTION:The purpose of this study was to determine factors and clinical situations that influence an endodontist's decision to use guided tissue regeneration (GTR) techniques during endodontic root-end surgery. METHODS:An invitation to participate in a web-based survey was e-mailed to 3,750 members of the America...

    journal_title:Journal of endodontics

    pub_type: 杂志文章


    authors: Naylor J,Mines P,Anderson A,Kwon D

    更新日期:2011-11-01 00:00:00

  • Association of black-pigmented bacteria with endodontic infections.

    abstract::Black-pigmented bacteria (BPB) have been associated with endodontic infections. The purpose of this study was to evaluate further the presence of BPB with the clinical signs and symptoms associated with endodontic infections. Microbial samples were collected from the root canals of 40 intact teeth with necrotic pulps ...

    journal_title:Journal of endodontics

    pub_type: 杂志文章


    authors: Baumgartner JC,Watkins BJ,Bae KS,Xia T

    更新日期:1999-06-01 00:00:00

  • Mandibular molar with 5 canals: report of a case.

    abstract::A unique case of a mandibular molar with 5 canals is described. Literature pertaining to the analysis of the morphology of mandibular first molars is reviewed. Clinicians should thoroughly examine the pulpal floor and radiographs for the possibility of additional canals. ...

    journal_title:Journal of endodontics

    pub_type: 杂志文章


    authors: DeGrood ME,Cunningham CJ

    更新日期:1997-01-01 00:00:00

  • An evidence-based analysis of the antibacterial effectiveness of intracanal medicaments.

    abstract::The authors reviewed the literature evaluating the antibacterial effectiveness of intracanal medicaments used in the management of apical periodontitis. A PICO (problem, intervention, comparison, outcome) strategy was developed to identify studies dealing with calcium hydroxide, phenolic derivatives, iodine-potassium ...

    journal_title:Journal of endodontics

    pub_type: 杂志文章


    authors: Law A,Messer H

    更新日期:2004-10-01 00:00:00

  • Antimicrobial activity of Ca(OH)2 containing pastes with Enterococcus faecalis in vitro.

    abstract::Sixty-eight standardized human root specimens were infected with Enterococcus faecalis for 3 wk after removal of the smear layer. After 3 wk of infection, the smear layer was reformed and in half of the specimens, the smear layer was again removed. Aqueous Ca(OH)2 paste and silicone oil based Ca(OH)2 paste were used a...

    journal_title:Journal of endodontics

    pub_type: 杂志文章


    authors: Han GY,Park SH,Yoon TC

    更新日期:2001-05-01 00:00:00

  • Effect of Diclofenac Potassium Premedication on Postendodontic Pain in Mandibular Molars with Symptomatic Irreversible Pulpitis: A Randomized Placebo-Controlled Double-Blind Trial.

    abstract:INTRODUCTION:The aim of this prospective, randomized, double-blind clinical trial was to evaluate the effect of a preoperative, single, oral dose of diclofenac potassium (DFK) on postoperative pain and rescue analgesic intake in patients with symptomatic irreversible pulpitis in mandibular molars treated in 1 visit. M...

    journal_title:Journal of endodontics

    pub_type: 杂志文章,随机对照试验


    authors: Al-Rawhani AH,Gawdat SI,Wanees Amin SA

    更新日期:2020-08-01 00:00:00

  • Association between Increased Inducible Costimulator/Inducible Costimulator Ligand Expression with Bone Destruction in Apical Periodontitis.

    abstract:INTRODUCTION:The aim was to assess the association of inducible costimulator (ICOS) and ICOS ligand with bone destruction in apical periodontitis (AP). METHODS:Specimens from patients presenting with AP were obtained during apicoectomy and subjected to histopathologic analysis and molecular assessment of ICOS/ICOS lig...

    journal_title:Journal of endodontics

    pub_type: 杂志文章


    authors: Tao YW,Xing Q,Li D,Quan J,Gao Y,Hu X,Zhang X

    更新日期:2019-07-01 00:00:00

  • Anesthetic efficacy of four percent articaine for pulpal anesthesia by using inferior alveolar nerve block and buccal infiltration techniques in patients with irreversible pulpitis: a prospective randomized double-blind clinical trial.

    abstract:INTRODUCTION:The study was designed as a randomized double-blind trial to evaluate the anesthetic efficacy of 4% articaine with 1:100,000 epinephrine in inferior alveolar nerve block (IANB) and infiltration anesthetic techniques to anesthetize mandibular molars with irreversible pulpitis. METHODS:The study was compose...

    journal_title:Journal of endodontics

    pub_type: 杂志文章,随机对照试验


    authors: Poorni S,Veniashok B,Senthilkumar AD,Indira R,Ramachandran S

    更新日期:2011-12-01 00:00:00

  • Electrochemical dissolution of nickel-titanium endodontic files induces periodontal ligament cell death.

    abstract:INTRODUCTION:Fractured endodontic files present a major problem. A novel method has been proposed to retrieve fractured nickel-titanium (NiTi) endodontic files by using electrochemical dissolution. However, the effect of file dissolution on adjacent soft tissues such as the periodontal ligament (PDL) has not been inves...

    journal_title:Journal of endodontics

    pub_type: 杂志文章


    authors: Mitchell Q,Jeansonne BG,Stoute D,Lallier TE

    更新日期:2013-05-01 00:00:00

  • Real-time quantitative polymerase chain reaction and culture analyses of Enterococcus faecalis in root canals.

    abstract::Reports on the prevalence of Enterococcus faecalis in root canals vary considerably, potentially because of variations in clinical sampling and sample analysis methods. This study compared culture and real-time quantitative polymerase chain reaction (qPCR) to detect and quantify E. faecalis in the same root canal samp...

    journal_title:Journal of endodontics

    pub_type: 杂志文章


    authors: Sedgley C,Nagel A,Dahlén G,Reit C,Molander A

    更新日期:2006-03-01 00:00:00

  • Regenerative capacity of human dental pulp and apical papilla cells after treatment with a 3-antibiotic mixture.

    abstract:INTRODUCTION:A 3-antibiotic combination (3Mix) has been widely used in regenerative endodontics. Recent studies recommend that a safe concentration of 3Mix is in the range of 0.39 μg/mL and 1 mg/mL because higher concentrations may limit tissue regeneration. The aim of this study was to determine the regenerative capac...

    journal_title:Journal of endodontics

    pub_type: 杂志文章


    authors: Phumpatrakom P,Srisuwan T

    更新日期:2014-03-01 00:00:00

  • Effect of tricalcium silicate on the proliferation and odontogenic differentiation of human dental pulp cells.

    abstract:INTRODUCTION:This study was to investigate the effects of tricalcium silicate (Ca(3)SiO(5)) on proliferation and odontogenic differentiation of human dental pulp cells (hDPCs) in vitro. METHODS:The hDPCs were seeded in culture medium with or without Ca(3)SiO(5) extract and calcium hydroxide (Ca(OH)(2)) extract. Prolif...

    journal_title:Journal of endodontics

    pub_type: 杂志文章


    authors: Peng W,Liu W,Zhai W,Jiang L,Li L,Chang J,Zhu Y

    更新日期:2011-09-01 00:00:00