Transformation of morphological, functional and metabolic properties of fast-twitch muscle as induced by long-term electrical stimulation.

Abstract:

:Transformation of structural, functional, metabolic and molecular characteristics is induced by stimulating fast-twitch muscles with the frequency pattern of a motoneuron normally innervating a slow-twitch muscle. These changes correspond to a transition of a "fast-white" into a "slow-red" muscle. Intermittent stimulation (8 h/d) does not affect the system but causes alterations of the sarcoplasmic reticulum which lead to changes in time to peak and half relaxation time. Continuous stimulation (24 h/d) induces a transformation of the muscle also at the level of the myosin system.

journal_name

Basic Res Cardiol

authors

Pette D,Heilmann C

doi

10.1007/BF01906369

subject

Has Abstract

pub_date

1977-03-01 00:00:00

pages

247-53

issue

2-3

eissn

0300-8428

issn

1435-1803

journal_volume

72

pub_type

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