Neurosurgery at the University of Michigan.

abstract：:After toxicity studies in dogs, a preliminary feasibility trial of the continuous intracranial infusion of a muscarinic agonist was begun in four patients with biopsy-documented Alzheimer's disease. During the last 8 months, a totally implantable infusion system has been used to deliver bethanechol chloride into the c...

journal_title：Neurosurgery

authors： Harbaugh RE,Roberts DW,Coombs DW,Saunders RL,Reeder TM

更新日期：1984-10-01 00:00:00

abstract：BACKGROUND:Markers of coagulation have shown to have important value in predicting traumatic brain injury outcome. OBJECTIVE:To externally validate and investigate the role of markers of coagulation for outcome prediction by using the International Mission for Prognosis and Analysis of Clinical Trials (IMPACT) model w...

journal_title：Neurosurgery

authors： Raj R,Siironen J,Kivisaari R,Hernesniemi J,Tanskanen P,Handolin L,Skrifvars MB

更新日期：2013-08-01 00:00:00

abstract：BACKGROUND:Although there are several large-species animal models for saccular aneurysms, there is a need for a simple, reproducible saccular aneurysm model in mice. OBJECTIVE:To develop a murine saccular aneurysm model, which replicates key characteristics that occur in the formation of human cerebral aneurysms. MET...

journal_title：Neurosurgery

authors： Hoh BL,Velat GJ,Wilmer EN,Hosaka K,Fisher RC,Scott EW

更新日期：2010-03-01 00:00:00

abstract：OBJECTIVE:Various techniques have been used to stop venous bleeding from the epidural space, vertebral venous plexus, and cavernous sinus. Here, we describe our experience with the use of fibrin glue to stop venous bleeding in these areas. METHODS:During the last 8 years, the senior author (LNS) has used injection of ...

journal_title：Neurosurgery

authors： Sekhar LN,Natarajan SK,Manning T,Bhagawati D

更新日期：2007-09-01 00:00:00

abstract：OBJECTIVE:Pediatric epilepsy surgery candidates with unilateral congenital or early-acquired brain lesions may present with refractory seizures and generalized electroencephalographic features such as electrical status epilepticus in sleep (ESES). The purpose of our study was to review the clinical presentation, neuroi...

journal_title：Neurosurgery

authors： Loddenkemper T,Cosmo G,Kotagal P,Haut J,Klaas P,Gupta A,Lachhwani DK,Bingaman W,Wyllie E

更新日期：2009-02-01 00:00:00

abstract：BACKGROUND:It is a prevalent myth that a postoperative infection may actually confer a survival advantage in patients with malignant glioma. This contention is based largely on anecdotal reports. Recently, a single-center study showed there was no survival advantage in those patients who had glioblastoma with postopera...

journal_title：Neurosurgery

authors： De Bonis P,Albanese A,Lofrese G,de Waure C,Mangiola A,Pettorini BL,Pompucci A,Balducci M,Fiorentino A,Lauriola L,Anile C,Maira G

更新日期：2011-10-01 00:00:00

abstract：BACKGROUND:Robot-assisted stereoelectroencephalography (SEEG) may represent a simplified, precise, and safe alternative to the more traditional SEEG techniques. OBJECTIVE:To report our clinical experience with robotic SEEG implantation and to define its utility in the management of patients with medically refractory e...

journal_title：Neurosurgery

authors： González-Martínez J,Bulacio J,Thompson S,Gale J,Smithason S,Najm I,Bingaman W

更新日期：2016-02-01 00:00:00

abstract：OBJECTIVE:Diffuse arteriovenous malformations (AVM) have non-compact niduses, irregular margins, and intervening brain parenchyma. Deep perforating arteries often contribute to the ragged border of these diffuse AVMs. We hypothesized that diffuseness and deep perforator supply increase the difficulties and risks associ...

journal_title：Neurosurgery

authors： Du R,Keyoung HM,Dowd CF,Young WL,Lawton MT

更新日期：2007-04-01 00:00:00

abstract：OBJECTIVE AND IMPORTANCE:Vertebrobasilar insufficiency resulting from disease of the subclavian artery is well recognized. Usually, this occurs as the "subclavian steal" syndrome in the context of chronic subclavian stenosis and is consequently well tolerated because of collateralization. Acute disruption of the hemody...

journal_title：Neurosurgery

authors： Amar AP,Levy ML,Giannotta SL

更新日期：1998-12-01 00:00:00

abstract：:Vittorio Marchi was an Italian neuroscientist who lived during the second half of the 19th century. He is generally remembered for developing a novel staining method to trace the degeneration of nervous fibers in lesions of the central nervous system. This osmium-based method was used worldwide for approximately a cen...

journal_title：Neurosurgery

authors： Talamonti G,D'Aliberti G,Debernardi A,Innocenti G

更新日期：2013-11-01 00:00:00

abstract：:The rete mirabile, a vascular network assumed to give origin to the intracranial segments of the internal carotid arteries, was interpreted by Galen as the key station for the conversion of the "vital spirit" into the "animal spirit." According to this interpretation, the rete was determinant either in sustaining the ...

journal_title：Neurosurgery

authors： Viale G

更新日期：2006-06-01 00:00:00

abstract：OBJECTIVE:The development of delayed ischemia caused by cerebral vasospasm remains a common cause of morbidity and mortality after aneurysmal subarachnoid hemorrhage. Preliminary studies suggest that 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors (statins) may decrease the risk of vasospasm, but additional ...

journal_title：Neurosurgery

authors： Kramer AH,Gurka MJ,Nathan B,Dumont AS,Kassell NF,Bleck TP

更新日期：2008-02-01 00:00:00

abstract：OBJECTIVE:Vestibular schwannomas present significant management challenges in patients with neurofibromatosis Type 2 (NF2). We evaluated the results of gamma knife radiosurgery for the management of these tumors, focusing on tumor response, hearing preservation, and other factors affecting outcomes. METHODS:Stereotact...

journal_title：Neurosurgery

authors： Mathieu D,Kondziolka D,Flickinger JC,Niranjan A,Williamson R,Martin JJ,Lunsford LD

更新日期：2007-03-01 00:00:00

abstract：OBJECTIVE:The treatment of residual and/or recurrent pituitary tumors, initially operated on through transsphenoidal and/or transcranial approaches, required a new single approach that would make it possible to excise the tumor from the sella and from the neighboring regions. Surgical complications, such as pneumatocep...

journal_title：Neurosurgery

authors： Dolenc VV

更新日期：1997-09-01 00:00:00

abstract：:Cerebral vascular tone is modulated, at least in part, by the vascular endothelium. This probably results from a balance between the release of the endothelium-derived relaxing factor(s) and the endothelium-derived constricting factor(s) (e.g., endothelin). The time course of the induction and the decay of these mutua...

journal_title：Neurosurgery

authors： Papadopoulos SM,Gilbert LL,Webb RC,D'Amato CJ

更新日期：1990-05-01 00:00:00

abstract：OBJECTIVE:The recent successful development of chronic stimulation of the motor cortex as a treatment for neuropathic and central pain does not exclude the possibility of eventual side effects, such as epileptic seizure or a lowering of the epileptic threshold. This study evaluates the behavioral and electroencephalogr...

journal_title：Neurosurgery

authors： Bezard E,Boraud T,Nguyen JP,Velasco F,Keravel Y,Gross C

更新日期：1999-08-01 00:00:00

abstract：OBJECTIVE:To evaluate diffusion tensor imaging (DTI)-based functional neuronavigation in surgery of cerebral gliomas with pyramidal tract (PT) involvement with respect to both perioperative assessment and follow-up outcome. METHODS:A prospective, randomized controlled study was conducted between 2001 and 2005. A conse...

journal_title：Neurosurgery

authors： Wu JS,Zhou LF,Tang WJ,Mao Y,Hu J,Song YY,Hong XN,Du GH

更新日期：2007-11-01 00:00:00

abstract：BACKGROUND:Intraprocedural rupture is a dangerous complication of endovascular treatment. Small ruptured anterior communicating artery (ACoA) aneurysms and microaneurysms present a challenge for both surgical and endovascular therapies to achieve obliteration. An understanding of the complication rates of treating rupt...

journal_title：Neurosurgery

authors： Schuette AJ,Hui FK,Spiotta AM,Obuchowski NA,Gupta R,Moskowitz SI,Tong FC,Dion JE,Cawley CM

更新日期：2011-03-01 00:00:00

abstract：OBJECTIVE:Embolization before surgical resection of tumors has been demonstrated to reduce intraoperative blood loss, but the optimal time that should elapse between embolization and tumor resection has not been established. We evaluated whether immediate surgical resection (< or =24 h) after embolization or delayed su...

journal_title：Neurosurgery

authors： Chun JY,McDermott MW,Lamborn KR,Wilson CB,Higashida R,Berger MS

更新日期：2002-06-01 00:00:00

abstract：OBJECTIVE AND IMPORTANCE:Herein we describe two cases of extracranial-intracranial vein graft bypasses for the treatment of giant intracranial aneurysms in prepubertal pediatric patients. One patient is, we think, the youngest patient reported in the literature to have been successfully treated in such a manner, with a...

journal_title：Neurosurgery

authors： Zhang YJ,Barrow DL,Day AL

更新日期：2002-03-01 00:00:00

abstract：OBJECTIVE:Resection of intracranial tumors in the posterior hippocampus and the parahippocampal gyrus can be associated with significant morbidity because of the parenchymal resection and the cortical retraction often required in gaining access to this infrequently explored region. With the use of image guidance, the o...

journal_title：Neurosurgery

authors： Russell SM,Kelly PJ

更新日期：2002-05-01 00:00:00

abstract：BACKGROUND:Epidemiological studies have indicated that postmenopausal women have a higher incidence of intracranial aneurysms than men in the same age group. OBJECTIVE:To investigate whether estrogen or estrogen receptors (ERs) mediate protective effects against the formation of intracranial aneurysms. METHODS:Intrac...

journal_title：Neurosurgery

authors： Tada Y,Makino H,Furukawa H,Shimada K,Wada K,Liang EI,Murakami S,Kudo M,Kung DK,Hasan DM,Kitazato KT,Nagahiro S,Lawton MT,Hashimoto T

更新日期：2014-12-01 00:00:00

abstract：BACKGROUND:Surgery for degenerative cervical spine disease has escalated since the 1990s. Fusion has become the mainstay of surgery despite concerns regarding adjacent segment degeneration. The patient-specific trends in reoperations have not been studied previously. OBJECTIVE:To analyze the occurrence, risk factors, ...

journal_title：Neurosurgery

authors： Kotkansalo A,Leinonen V,Korajoki M,Korhonen K,Rinne J,Malmivaara A

更新日期：2020-12-28 00:00:00

abstract：BACKGROUND:Meningeal hemangiopericytoma (M-HPC) is a rare entity. OBJECTIVE:To characterize our institutional experience in treating M-HPC. METHODS:We reviewed the medical records of patients with M-HPC evaluated at The University of Texas M.D. Anderson Cancer Center between 1979 and 2009. RESULTS:We identified 63 p...

journal_title：Neurosurgery

authors： Ghia AJ,Chang EL,Allen PK,Mahajan A,Penas-Prado M,McCutcheon IE,Brown PD

更新日期：2013-10-01 00:00:00

abstract：:This study examines the pathophysiology of stroke secondary to focal cerebral ischemia. The interaction of arachidonic acid metabolites and polyamines, a class of ubiquitous ornithine-derived molecules with important membrane effects on edema, Ca++-dependent endocytosis, platelet function, and prostaglandin (PG) forma...

journal_title：Neurosurgery

authors： Dempsey RJ,Roy MW,Meyer K,Tai HH,Olson JW

更新日期：1985-10-01 00:00:00

abstract：BACKGROUND:Targeted stereotactic radiosurgery (SRS) with sparing of the residual pituitary is the traditional radiosurgical method for pituitary adenomas. Whole-sella SRS is an alternative choice for radiologically indeterminate or large adenomas, the safety and efficacy of which has yet to be determined. OBJECTIVE:To...

journal_title：Neurosurgery

authors： Taylor DG,Janssen A,Ding D,Xu Z,Mehta GU,Liscak R,Kano H,Kosak M,Martinez-Moreno N,Hobbs L,Chen CJ,Grills IS,Mathieu D,Lunsford LD,Vance ML,Sheehan JP

更新日期：2020-05-01 00:00:00

abstract：:: The US health care system is struggling with rising costs, poor outcomes, waste, and inefficiency. The Patient Protection and Affordable Care Act represents a substantial effort to improve access and emphasizes value-based care. Value in health care has been defined as health outcomes for the patient per dollar spen...

journal_title：Neurosurgery

authors： Smith TR,Rambachan A,Cote D,Cybulski G,Laws ER

更新日期：2015-10-01 00:00:00

abstract：BACKGROUND:Anterior cingulotomy (AC) can be an effective therapy for patients with severe obsessive-compulsive disorder who are refractory to traditional medical therapy. For patients who do not respond to AC, the benefit of additional lesion procedures vs continued medical management remains unknown. OBJECTIVE:To det...

journal_title：Neurosurgery

authors： Bourne SK,Sheth SA,Neal J,Strong C,Mian MK,Cosgrove GR,Eskandar EN,Dougherty DD

更新日期：2013-02-01 00:00:00

abstract：BACKGROUND:Frontotemporal craniotomies are commonly performed for a variety of neurosurgical pathologies. Infections related to craniotomies cause significant morbidity. We hypothesized that the risk of cranial surgical site infections (SSIs) may be increased in patients whose frontal sinuses are breached during cranio...

journal_title：Neurosurgery

authors： Linzey JR,Wilson TJ,Sullivan SE,Thompson BG,Pandey AS

更新日期：2017-09-01 00:00:00

abstract：OBJECTIVE:The release of results of International Subarachnoid Aneurysm Trial in 2003 caused a shift in the paradigm of management of ruptured intracranial aneurysms. The cases selected for microsurgical clipping nowadays are usually those patients with aneurysms that are not suitable for embolization, and are often co...

journal_title：Neurosurgery

authors： Wong GK,Zhu CX,Ahuja AT,Poon WS

更新日期：2007-09-01 00:00:00