Sequence analysis of the complete mitochondrial DNA molecule of the hedgehog, Erinaceus europaeus, and the phylogenetic position of the Lipotyphla.

abstract：:The question of whether natural selection favors genetic stability or genetic variability is a fundamental problem in evolutionary biology. Bioinformatic analyses demonstrate that selection favors genetic stability by avoiding unstable nucleotide sequences in protein encoding DNA. Yet, such unstable sequences are main...

journal_title：Journal of molecular evolution

authors： Falster DS,Nakken S,Bergem-Ohr M,Rødland EA,Breivik J

更新日期：2010-03-01 00:00:00

abstract：:The retrieval of Neanderthal (Homo neanderthalsensis) mitochondrial DNA is thought to be among the most significant ancient DNA contributions to date, allowing conflicting hypotheses on modern human (Homo sapiens) evolution to be tested directly. Recently, however, both the authenticity of the Neanderthal sequences an...

journal_title：Journal of molecular evolution

authors： Hebsgaard MB,Wiuf C,Gilbert MT,Glenner H,Willerslev E

更新日期：2007-01-01 00:00:00

abstract：:We examined the cis- vs. trans-splicing status of the mitochondrial group II intron nad1i728 in 439 species (427 genera) of land plants, using both Southern hybridization results (for 416 species) and intron sequence data from the literature. A total of 164 species (157 genera), all angiosperms, was found to have a tr...

journal_title：Journal of molecular evolution

authors： Qiu YL,Palmer JD

更新日期：2004-07-01 00:00:00

abstract：:Many proteins exhibit sequence periodicity, often correlated with a visible structural periodicity. The statistical significance of such periodicity can be assessed by means of a chi-squared-based test, with significance thresholds being calculated from shuffled sequences. Comparison of the complete proteomes of 45 sp...

journal_title：Journal of molecular evolution

authors： Gatherer D,McEwan NR

更新日期：2005-04-01 00:00:00

abstract：:Fish protamines are highly specialized molecules which are responsible for chromatin condensation during the last stages of spermatogenesis (spermiogenesis). However, not all fish contain protamines in their sperm nuclei; rather, there seems to be a random distribution of protamines within this group. The origin of th...

journal_title：Journal of molecular evolution

authors： Saperas N,Ausio J,Lloris D,Chiva M

更新日期：1994-09-01 00:00:00

abstract：:Covarion processes allow changes in evolutionary rates at sites along the branches of a phylogenetic tree. Covarion-like evolution is increasingly recognized as an important mode of protein evolution. Several recent reports suggest that maximum likelihood estimation employing covarion models may support different opti...

journal_title：Journal of molecular evolution

authors： Wang HC,Susko E,Spencer M,Roger AJ

更新日期：2008-01-01 00:00:00

abstract：:EcoRI restriction of the B. nigra rDNA recombinants, isolated from a lambda genomic library, showed that the 3.9-kb fragment corresponded to the Intergenic Spacer (IGS), which was sequenced and found to be 3,928 bp in size. Sequence and dot-matrix analyses showed that the organization of the B. nigra rDNA IGS was typi...

journal_title：Journal of molecular evolution

authors： Bhatia S,Singh Negi M,Lakshmikumaran M

更新日期：1996-11-01 00:00:00

abstract：:We present a new approach for analyzing directional mutation pressure and nucleotide content in protein-coding genes. Directional mutation pressure, the heterogenicity in the likelihood of different nucleotide substitutions, is used to explain the increasing or decreasing guanine-cytosine content (GC%) in DNA and is r...

journal_title：Journal of molecular evolution

authors： Jermiin LS,Graur D,Lowe RM,Crozier RH

更新日期：1994-08-01 00:00:00

abstract：:Catalyzed polymerization reactions represent a primary anabolic activity of all cells. It can be assumed that early cells carried out such reactions, in which macromolecular catalysts were encapsulated within some type of boundary membrane. In the experiments described here, we show that a template-independent RNA pol...

journal_title：Journal of molecular evolution

authors： Chakrabarti AC,Breaker RR,Joyce GF,Deamer DW

更新日期：1994-12-01 00:00:00

abstract：:Sequence data from regions of five vertebrate vitellogenin genes were used to examine the frequency, distribution, and mutability of the dinucleotide CpG, the preferred modification site for eukaryotic DNA methyltransferases. The observed level of the CpG dinucleotide in all five genes was markedly lower than that exp...

journal_title：Journal of molecular evolution

authors： Cooper DN,Gerber-Huber S,Nardelli D,Schubiger JL,Wahli W

更新日期：1987-01-01 00:00:00

abstract：:This study examines the diverse maximum wavelength absorption (lambdamax) found in crayfishes (Decapoda: Cambaridae and Parastacidae) and the associated genetic variation in their opsin locus. We measured the wavelength absorption in the photoreceptors of six species that inhabit environments of different light intens...

journal_title：Journal of molecular evolution

authors： Crandall KA,Cronin TW

更新日期：1997-11-01 00:00:00

abstract：:Alu elements are not distributed homogeneously throughout the human genome: old elements are preferentially found in the GC-rich parts of the genome, while young Alus are more often found in the GC-poor parts of the genome. The process giving rise to this differential distribution remains poorly understood. Here we in...

journal_title：Journal of molecular evolution

authors： Belle EM,Webster MT,Eyre-Walker A

更新日期：2005-03-01 00:00:00

abstract：:The human Rh blood group locus consists of two structurally related genes (D and CcEe) in Rh-positive haplotypes but a single gene (CcEe) in Rh-negative haplotypes. The genome of rhesus monkeys (Macaca mulatta), while not expressing any of the human Rh D, C, c, E, or e specificities, carries a Rh-like locus strongly r...

journal_title：Journal of molecular evolution

authors： Mouro I,Le Van Kim C,Cherif-Zahar B,Salvignol I,Blancher A,Cartron JP,Colin Y

更新日期：1994-02-01 00:00:00

abstract：:Exon-shuffling is an important mechanism accounting for the origin of many new proteins in eukaryotes. However, its role in the creation of proteins in the ancestor of prokaryotes and eukaryotes is still debatable. Excess of symmetric exons is thought to represent evidence for exon-shuffling since the exchange of exon...

journal_title：Journal of molecular evolution

authors： Vibranovski MD,Sakabe NJ,de Oliveira RS,de Souza SJ

更新日期：2005-09-01 00:00:00

abstract：:Gamete-recognition proteins have been shown to evolve by positive selection in diverse organism groups, such as marine invertebrates and mammals, although underlying evolutionary mechanisms driving this rapid divergence are poorly understood. However, several hypotheses have been put forward to explain the observed pa...

journal_title：Journal of molecular evolution

authors： Berlin S,Qu L,Ellegren H

更新日期：2008-11-01 00:00:00

abstract：:Polymerization of various nucleoside-5'-phosphorimidazolides has been conducted in neutral aqueous solution using divalent metal ions as catalysts. Oligonucleotide formation took place from each of the ribonucleoside-5'-phosphorimidazolides, ImpC, ImpU, ImpA, ImpG, and ImpI. The yields and distributions of the resulti...

journal_title：Journal of molecular evolution

authors： Sawai H

更新日期：1988-01-01 00:00:00

abstract：:As the origin(s) of life on Earth remains an open question, detailed characteristics about the "last universal ancestor" (LUA) continue to be obscured. Here we provide arguments that strengthen the bacterial-like nature of the LUA. Our view attempts to recreate the evolution of archaeal lipids, the major components of...

journal_title：Journal of molecular evolution

authors： Payandeh J,Pai EF

更新日期：2007-03-01 00:00:00

abstract：:We have previously shown that several multicopy gene families within the major histocompatibility complex (MHC) arose from a process of segmental duplication. It has also been observed that retroelements play a role in generating diversity within these duplicated segments. The objective of this study was to compare th...

journal_title：Journal of molecular evolution

authors： Freitas EM,Gaudieri S,Zhang WJ,Kulski JK,van Bockxmeer FM,Christiansen FT,Dawkins RL

更新日期：2000-04-01 00:00:00

abstract：:We have determined the genomic structure of an integrin beta-subunit gene from the coral, Acropora millepora. The coding region of the gene contains 26 introns, spaced relatively uniformly, and this is significantly more than have been found in any integrin beta-subunit genes from higher animals. Twenty-five of the 26...

journal_title：Journal of molecular evolution

authors： Schmitt DM,Brower DL

更新日期：2001-12-01 00:00:00

abstract：:Abortive cycling features transcription initiation by RNA polymerase in both prokaryote and eukaryote. It is known that T7 RNA polymerase produces abortive transcripts up to eight ribonucleotides in length depending on the initial sequence of the DNA message. On the other hand, T7 RNA polymerase initiates DNA replicat...

journal_title：Journal of molecular evolution

authors： Matsumoto J

更新日期：1994-12-01 00:00:00

abstract：:Ornithine decarboxylase (ODC) is the first enzyme in the polyamine biosynthetic pathway. We have studied the evolutionary history of the mammalian ODC mRNA, focusing on the rate of accumulation of sequence divergence within specific subregions of the molecule. The phylogenetic relationships among the mRNAs from severa...

journal_title：Journal of molecular evolution

authors： Johannes GJ,Berger FG

更新日期：1993-06-01 00:00:00

abstract：:A new type of repeat unit was isolated from Balbiani ring 1 of Chironomus pallidivittatus and designated BR1 beta repeat. It consists of a constant and a subrepeated part, like previously described units belonging to the core blocks of the BR genes. The subrepeated part contains 10-codon subrepeats with an arrangement...

journal_title：Journal of molecular evolution

authors： Saiga H,Botella L,Edström JE

更新日期：1988-01-01 00:00:00

abstract：:We have studied the metal-ion catalysis of a number of reactions of the isomers of ImpGpG on a poly(C) template. In the absence of a catalytic metal ion, oligomers at least up to (pG)20 are obtained from the ImpGpG isomers in a 1-methylimidazole buffer. The Pb2+ ion improves the yield of longer oligomers and changes s...

journal_title：Journal of molecular evolution

authors： Lohrmann R,Bridson PK,Orgel LE

更新日期：1981-01-01 00:00:00

abstract：:Ca(2+)/cation antiporter (CaCA) proteins are integral membrane proteins that transport Ca(2+) or other cations using the H(+) or Na(+) gradient generated by primary transporters. The CAX (for CAtion eXchanger) family is one of the five families that make up the CaCA superfamily. CAX genes have been found in bacteria, ...

journal_title：Journal of molecular evolution

authors： Shigaki T,Rees I,Nakhleh L,Hirschi KD

更新日期：2006-12-01 00:00:00

abstract：:Skin pigmentation is a complex, conspicuous, highly variable human trait that exhibits a remarkable correlation with latitude. The evolutionary history and genetic basis of skin color variation has been the subject of intense research in the last years. This article reviews the major hypotheses explaining skin color d...

journal_title：Journal of molecular evolution

authors： Rocha J

更新日期：2020-01-01 00:00:00

abstract：:The phylogenetic relationships among Primates (human), Artiodactyla (cow), Cetacea (whale), Carnivora (seal), and Rodentia (mouse and rat) were estimated from the inferred amino acid sequences of the mitochondrial genomes using Marsupialia (opossum), Aves (chicken), and Amphibia (Xenopus) as an outgroup. The overall e...

journal_title：Journal of molecular evolution

authors： Cao Y,Adachi J,Janke A,Pääbo S,Hasegawa M

更新日期：1994-11-01 00:00:00

abstract：:The in vitro expression of two distinct proteins from overlapping reading frames in a sequence of rainbow trout genomic DNA has been demonstrated. In vitro transcription of DNA sequences, cloned in a plasmid under the control of Salmonella phage 6 polymerase promoter, led to the synthesis of two distinct and functiona...

journal_title：Journal of molecular evolution

authors： Jankowski JM,Krawetz SA,Walczyk E,Dixon GH

更新日期：1986-01-01 00:00:00

abstract：:The nucleotide sequences of 5S rRNAs from three protozoa, Bresslaua vorax, Euplotes woodruffi and Chlamydomonas sp. have been determined and aligned together with the sequences of 12 protozoa species including unicellular green algae already reported by the authors and others. Using this alignment, a phylogenic tree o...

journal_title：Journal of molecular evolution

authors： Kumazaki T,Hori H,Osawa S

更新日期：1983-01-01 00:00:00

abstract：:Analysis of the expanded data set of Sibley and Ahlquist (1987) on primate phylogeny using a maximum likelihood mixed model analysis of variance method shows that there is significant evidence for resolving the Homo-Pan-Gorilla trifurcation in favor of a Homo-Pan clade. The resulting tree is close to that estimated by...

journal_title：Journal of molecular evolution

authors： Felsenstein J

更新日期：1987-01-01 00:00:00

abstract：:Antibody binding site are formed by six hypervariable regions or complementarity determining regions (CDRs). The CDRs, three from the heavy chain and three from the light chain, are known as hypervariable segments and provide a surface complementary to that of the epitope. In recent work it was found that the amino ac...

journal_title：Journal of molecular evolution

authors： Vargas-Madrazo E,Lara-Ochoa F,Jiménez-Montaño M

更新日期：1994-01-01 00:00:00