Factors associated with different responses to periodontal therapy.

Abstract:

:In a study of the efficacy of modified Widman flap surgery and scaling and root planning accompanied by 1 of 4 systemic adjunctive agents, Augmentin, tetracycline, ibuprofen or placebo, it was observed that subjects differed in their response to therapy. The difference was only partially accounted for by the adjunctive agent employed. The purpose of the present investigation was to examine clinical and microbiological features in subjects who showed different levels of attachment change post-therapy. 40 subjects were subset into 3 groups based on mean attachment level change post-therapy. 10 poor response subjects showed mean attachment loss; 19 moderate response subjects showed mean attachment gain between 0.02-0.5 mm and 11 good response subjects showed a mean gain of attachment > 0.5 mm. Clinical parameters were measured at 6 sites per tooth both pre- and post-therapy. Microbiological samples were taken from the mesial aspect of each tooth and evaluated individually for their content of 14 subgingival taxa using a colony lift method and DNA probes. % of sites colonized by each species was computed for each subject both pre- and post-therapy. Significant differences were observed among treatment response groups for mean probing pocket depth, attachment level and % of sites with plaque pre-therapy. The poor response subjects had the lowest mean probing pocket depth and attachment level, but the highest plaque levels. Post-therapy, the poor response group exhibited the greatest degree of gingival inflammation as assessed by gingival redness and bleeding on probing.(ABSTRACT TRUNCATED AT 250 WORDS)

journal_name

J Clin Periodontol

authors

Haffajee AD,Dibart S,Kent RL Jr,Socransky SS

doi

10.1111/j.1600-051x.1995.tb00816.x

subject

Has Abstract

pub_date

1995-08-01 00:00:00

pages

628-36

issue

8

eissn

0303-6979

issn

1600-051X

journal_volume

22

pub_type

临床试验,杂志文章
  • Squamous odontogenic tumor (SOT): a benign neoplasm of the periodontium. A review of 36 reported cases.

    abstract::True neoplasms are rarely localised to the periodontium. However, early recognition and diagnosis of neoplastic lesions resides within the realm of responsibility of the dentist. In recent years, a number of odontogenic tumors has been described characterized by an occurrence on the gingiva or in the intrabony part of...

    journal_title:Journal of clinical periodontology

    pub_type: 杂志文章,评审

    doi:10.1111/j.1600-051x.1996.tb00512.x

    authors: Philipsen HP,Reichart PA

    更新日期:1996-10-01 00:00:00

  • Effects of smoking and gingival inflammation on salivary antioxidant capacity.

    abstract:AIM:This study evaluated possible effects of smoking and gingival inflammation on salivary antioxidants in gingivitis patients. METHODS:Twenty otherwise healthy gingivitis patients (10 self-reported smokers) and 20 periodontally and systemically healthy volunteer subjects were enrolled in the study. Whole saliva sampl...

    journal_title:Journal of clinical periodontology

    pub_type: 杂志文章

    doi:10.1111/j.1600-051X.2006.00892.x

    authors: Buduneli N,Kardeşler L,Işik H,Willis CS 3rd,Hawkins SI,Kinane DF,Scott DA

    更新日期:2006-03-01 00:00:00

  • The relationship of gingival crevicular fluid short chain carboxylic acid concentration to gingival inflammation.

    abstract::Short-chain carboxylic acids (SCCA; C < or = 5; e.g., lactic acid, propionic acid, butyric acid) are metabolic by-products of bacterial metabolism which accumulate in the gingival crevice, and exhibit significant biological activity, including the ability to alter gene expression. It has been hypothesized that among t...

    journal_title:Journal of clinical periodontology

    pub_type: 杂志文章

    doi:10.1111/j.1600-051x.1996.tb00604.x

    authors: Niederman R,Buyle-Bodin Y,Lu BY,Naleway C,Robinson P,Kent R

    更新日期:1996-08-01 00:00:00

  • Particulate bioglass as a grafting material in the treatment of periodontal intrabony defects.

    abstract::The present clinical trial was designed to evaluate the effects of a bioactive glass, Perioglas, in the treatment of periodontal intrabony defects. 20 patients, 23-55 years of age (44 sites), with intrabony defects completed the 1-year study. Teeth with furcation involvement were excluded. After completion of initial ...

    journal_title:Journal of clinical periodontology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1111/j.1600-051x.1997.tb00205.x

    authors: Zamet JS,Darbar UR,Griffiths GS,Bulman JS,Brägger U,Bürgin W,Newman HN

    更新日期:1997-06-01 00:00:00

  • Sulfate-reducing bacteria in periodontal pockets and in healthy oral sites.

    abstract::The aim of this study was to monitor the presence of sulfate-reducing bacteria (SRB) at different sites in the mouths of both healthy individuals and periodontitis patients. In 20 healthy subjects and 21 periodontitis patients, samples were taken from the palate, vestibulum, dorsum of the tongue, supragingival plaque,...

    journal_title:Journal of clinical periodontology

    pub_type: 杂志文章

    doi:10.1034/j.1600-051x.1999.260906.x

    authors: Langendijk PS,Hagemann J,van der Hoeven JS

    更新日期:1999-09-01 00:00:00

  • Mandibular and maxillary furcation tunnel preparations--literature review and a case report.

    abstract:AIM:The objective of this literature review and subsequent case report is to discuss and illustrate the tunnel preparation procedure as a treatment alternative for furcation-involved molars. REVIEW OF THE LITERATURE:Furcation tunnel preparation, i.e., the creation of access for plaque control between periodontally dis...

    journal_title:Journal of clinical periodontology

    pub_type: 杂志文章,评审

    doi:

    authors: Rüdiger SG

    更新日期:2001-01-01 00:00:00

  • Mandibular reconstruction using a calcium phosphate/polyethylene glycol hydrogel carrier with BMP-2.

    abstract:AIM:To test the hypothesis that a synthetic hydroxyapatite/β-tricalcium phosphate (HA/TCP) construct combined with polyethylene glycol (PEG) hydrogel including recombinant human bone morphogenetic proteins-2 (rhBMP-2) enhances new bone formation compared with bone morphogenetic proteins-2 (BMP-2) delivered using the HA...

    journal_title:Journal of clinical periodontology

    pub_type: 杂志文章

    doi:10.1111/jcpe.12264

    authors: Gruber RM,Krohn S,Mauth C,Dard M,Molenberg A,Lange K,Perske C,Schliephake H

    更新日期:2014-08-01 00:00:00

  • Epithelial remnants in the crestal periodontium of the deciduous and permanent dentition of beagle dogs.

    abstract::The purpose of this study was to document and characterize epithelial remnants (EPRs) of the crestal periodontium of the deciduous dentition of a diphyodont and compare them with EPR units found in the corresponding area of the permanent dentition. 7 beagle dogs were used. At the age of 10 weeks (deciduous dentition) ...

    journal_title:Journal of clinical periodontology

    pub_type: 杂志文章

    doi:10.1111/j.1600-051x.1994.tb00754.x

    authors: Sterrett JD,Berglundh T,Lindhe J

    更新日期:1994-10-01 00:00:00

  • Depth of alveolar bone dehiscences in relation to gingival recessions.

    abstract::Dehiscence depths were measured in vivo during surgical treatment of 113 teeth with gingival recession in 27 subjects. The average dehiscence depth determined was 5.43 mm with an average recession depth of 2.67 mm. Statistical evidence of a correlation between recession depth and dehiscence depth (average distance bet...

    journal_title:Journal of clinical periodontology

    pub_type: 杂志文章

    doi:10.1111/j.1600-051x.1984.tb00911.x

    authors: Löst C

    更新日期:1984-10-01 00:00:00

  • A radiographic survey of periodontal conditions in Greece.

    abstract::The present study used radiographic assessments to evaluate the pattern of destructive periodontal disease ina rural and an urban sample of 25-64 year old Greek adults. The rural sample (A) comprised 190 subjects and the urban sample (B) 400 subjects. 13% of the subjects in sample A and 8% in sample B were edentulous....

    journal_title:Journal of clinical periodontology

    pub_type: 杂志文章

    doi:10.1111/j.1600-051x.1995.tb00165.x

    authors: Diamanti-Kipioti A,Afentoulidis N,Moraitaki-Tsami A,Lindhe J,Mitsis F,Papapanou PN

    更新日期:1995-05-01 00:00:00

  • Variation in periodontal referral by general dental practitioners.

    abstract::This study investigated the extent of and reasons for variation in the periodontal referral patterns of general dental practitioners in Northern Ireland. A questionnaire was circulated to all general dental practitioners in Northern Ireland. This questionnaire investigated the management of periodontal disease in the ...

    journal_title:Journal of clinical periodontology

    pub_type: 杂志文章

    doi:10.1111/j.1600-051x.1998.tb02502.x

    authors: Linden GJ

    更新日期:1998-08-01 00:00:00

  • Effects of tetracycline hydrochloride and chlorhexidine gluconate on Candida albicans. An in vitro study.

    abstract::This study examined the effects of tetracycline hydrochloride (TCN) and chlorhexidine gluconate (CHX) on the growth and viability of Candida albicans. Subcultures of Candida albicans on Sabouraud's agar, were divided into 5 treatment groups: group 1, untreated control; group 2, 0.12% CHX; group 3, 3.0 mg/ml TCN adjust...

    journal_title:Journal of clinical periodontology

    pub_type: 杂志文章

    doi:10.1111/j.1600-051x.1997.tb00193.x

    authors: MacNeill S,Rindler E,Walker A,Brown AR,Cobb CM

    更新日期:1997-10-01 00:00:00

  • Sinus augmentation using rhBMP-2/ACS in a mini-pig model: Influence of an adjunctive ceramic bone biomaterial.

    abstract:BACKGROUND:Recombinant human bone morphogenetic protein-2 in an absorbable collagen sponge carrier (rhBMP-2/ACS) has been shown to support significant bone formation when used to augment the maxillary sinus for implant dentistry. Nevertheless, bone biomaterials have been suggested to extend rhBMP-2/ACS with limited sup...

    journal_title:Journal of clinical periodontology

    pub_type: 杂志文章

    doi:10.1111/jcpe.12921

    authors: Susin C,Lee J,Fiorini T,de Freitas RM,Chiu HC,Prasad HS,Buxton AN,Wikesjö UM

    更新日期:2018-08-01 00:00:00

  • The validity and reproducibility of an oral rating index as a measurement of gingival health care and oral hygiene level in adults.

    abstract::The purpose of this study was to investigate the validity and reproducibility of an oral rating index (ORI) as a conceptual measurement of "gingival health care" level in adults. The study was conducted on 163 patients who received medical examinations and attended for dental checkups at a hospital. The score of the O...

    journal_title:Journal of clinical periodontology

    pub_type: 杂志文章

    doi:10.1034/j.1600-051x.2000.027006411.x

    authors: Kawamura M,Fukuda S,Inoue C,Sasahara H,Iwamoto Y

    更新日期:2000-06-01 00:00:00

  • Inhibition of fibroblast attachment.

    abstract::Reattachment is at present an ephemeral goal. There is, therefore, much interest in clarifying the events which determine patterns of cellular repopulation of denuded cementum during periodontal healing, and thus determine the outcome of reattachment surgery. It has previously been reported that human saliva inhibits ...

    journal_title:Journal of clinical periodontology

    pub_type: 杂志文章

    doi:10.1111/j.1600-051x.1986.tb01438.x

    authors: Heaney TG

    更新日期:1986-11-01 00:00:00

  • Association between serum lipid levels and periodontal infection.

    abstract:OBJECTIVE:The aim of the study was to investigate the association between serum lipids and periodontal infection and the role of serum lipids in the association between body weight and periodontal infection. MATERIAL AND METHODS:The Health 2000 Health Examination Survey, which included 8028 subjects aged 30 or older l...

    journal_title:Journal of clinical periodontology

    pub_type: 杂志文章

    doi:10.1111/j.1600-051X.2008.01331.x

    authors: Saxlin T,Suominen-Taipale L,Kattainen A,Marniemi J,Knuuttila M,Ylöstalo P

    更新日期:2008-12-01 00:00:00

  • The effect of haemostatic agents on early healing of the extraction socket.

    abstract:AIM:This study aims to explore the effect of two commercially available haemostatic agents (i.e., collagen sponge and oxide cellulose) on early healing of the extraction socket. MATERIAL AND METHODS:In a murine model, bilateral maxillary first molars were extracted and the sockets were filled with or without haemostat...

    journal_title:Journal of clinical periodontology

    pub_type: 杂志文章

    doi:10.1111/jcpe.13122

    authors: Guo X,Hu H,Liu Y,Bao C,Wang L

    更新日期:2019-07-01 00:00:00

  • Oral health and changes in lipid profile: A nationwide cohort study.

    abstract:AIM:We aimed to investigate the association of periodontitis and oral hygiene indicators with changes in blood lipid parameters in a nationwide, population-based cohort in a longitudinal setting. MATERIALS AND METHODS:We included nationwide health screening program participants who underwent oral health examination in...

    journal_title:Journal of clinical periodontology

    pub_type: 杂志文章

    doi:10.1111/jcpe.13373

    authors: Song TJ,Kim JW,Kim J

    更新日期:2020-12-01 00:00:00

  • A prospective longitudinal study on periodontal bone height changes in a Swedish population.

    abstract:BACKGROUND, AIMS:This investigation was performed to assess longitudinal changes in periodontal bone height in an adult population over a period of 17 years. METHODS:In 1973, a random sample of 1000 individuals aged 3-70 years in the city of Jönköping, Sweden, was examined clinically and radiographically to assess den...

    journal_title:Journal of clinical periodontology

    pub_type: 杂志文章

    doi:10.1034/j.1600-051x.2000.027009665.x

    authors: Hugoson A,Laurell L

    更新日期:2000-09-01 00:00:00

  • Aesthetic crown lengthening: periodontal and patient-centred outcomes.

    abstract:AIM:The objective of this prospective study was to assess clinical and patient-centred outcomes of aesthetic crown lengthening surgery for the treatment of altered passive eruption. MATERIALS AND METHODS:Twenty-two patients were treated and followed up for 6 months. The evaluated clinical parameters included, among ot...

    journal_title:Journal of clinical periodontology

    pub_type:

    doi:10.1111/jcpe.12482

    authors: Silva CO,Soumaille JM,Marson FC,Progiante PS,Tatakis DN

    更新日期:2015-12-01 00:00:00

  • Supportive periodontal therapy of furcation sites: non-surgical instrumentation with or without topical doxycycline.

    abstract:OBJECTIVES:Evaluation of the clinical effect of topical subgingival application of doxycycline gel adjunctively to scaling and root planing (SRP) at furcation sites during supportive periodontal therapy (SPT). MATERIAL AND METHODS:In 39 SPT patients exhibiting at least four pockets > or m with bleeding on probing, SRP...

    journal_title:Journal of clinical periodontology

    pub_type: 杂志文章,随机对照试验

    doi:10.1111/j.1600-051X.2009.01414.x

    authors: Dannewitz B,Lippert K,Lang NP,Tonetti MS,Eickholz P

    更新日期:2009-06-01 00:00:00

  • Effects of smoking on local delivery of controlled-release doxycycline as compared to scaling and root planing.

    abstract::This paper examines the effects of smoking on the treatment outcomes of two nonsurgical therapies: (1) scaling and root planing alone (SRP) or (2) controlled-release of subgingivally delivered doxycycline hyclate in a polylactic acid based polymer gel. Subjects from 2 9-month multicenter studies were classified as non...

    journal_title:Journal of clinical periodontology

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验

    doi:10.1034/j.1600-051x.1999.261008.x

    authors: Ryder MI,Pons B,Adams D,Beiswanger B,Blanco V,Bogle G,Donly K,Hallmon W,Hancock EB,Hanes P,Hawley C,Johnson L,Wang HL,Wolinsky L,Yukna R,Polson A,Carron G,Garrett S

    更新日期:1999-10-01 00:00:00

  • Gingival hyperplasia in renal allograft recipients receiving cyclosporin-A and calcium antagonists.

    abstract::Although it is established that the immunosuppressant cyclosporin-A (CsA) and calcium antagonists [Nifedipine (Nif) and Diltiazem (Dz)] can independently induce gingival enlargement, little has been documented on the significance of the salivary CsA levels and the combined effect of CsA and a calcium antagonist upon g...

    journal_title:Journal of clinical periodontology

    pub_type: 杂志文章

    doi:10.1111/j.1600-051x.1993.tb00360.x

    authors: King GN,Fullinfaw R,Higgins TJ,Walker RG,Francis DM,Wiesenfeld D

    更新日期:1993-04-01 00:00:00

  • Host response to microbial challenge following resective/non-resective periodontal therapy.

    abstract:BACKGROUND:The host response to microbial challenge depends on the recruitment of homing leucocytes and may be related to the experience to infectious insults over years. PURPOSE:The aim of this study was to investigate the soft tissue reactions to de novo plaque formation at sites treated with either open flap debrid...

    journal_title:Journal of clinical periodontology

    pub_type: 杂志文章,随机对照试验

    doi:10.1111/j.1600-051X.2005.00746.x

    authors: Zitzmann NU,Lindhe J,Berglundh T

    更新日期:2005-11-01 00:00:00

  • Ridge regeneration of damaged extraction sockets using rhBMP-2: an experimental study in canine.

    abstract:OBJECTIVES:This study evaluated the dimensional ridge alteration in a buccal-bone-deficient extraction socket, and ridge regeneration following socket grafting accompanied by recombinant human bone morphogenetic protein 2 (rhBMP-2) or a collagen membrane covering. MATERIAL AND METHODS:In five beagle dogs, entire bucca...

    journal_title:Journal of clinical periodontology

    pub_type: 杂志文章

    doi:10.1111/jcpe.12414

    authors: Lee JS,Jung JS,Im GI,Kim BS,Cho KS,Kim CS

    更新日期:2015-07-01 00:00:00

  • Prevalence of tetM, tetQ, nim and bla(TEM) genes in the oral cavities of Greek subjects: a pilot study.

    abstract:AIM:To investigate the prevalence of tetM, tetQ, nim and bla(TEM) antimicrobial resistance genes in subgingival and tongue samples of Greek subjects. MATERIALS AND METHODS:Fifty-four subjects participated in the present study. Participants each contributed with one pooled subgingival sample from the mesiobuccal surfac...

    journal_title:Journal of clinical periodontology

    pub_type: 杂志文章

    doi:10.1111/j.1600-051X.2009.01425.x

    authors: Ioannidis I,Sakellari D,Spala A,Arsenakis M,Konstantinidis A

    更新日期:2009-07-01 00:00:00

  • Periodontitis and arterial stiffness: a systematic review and meta-analysis.

    abstract:INTRODUCTION AND AIMS:Patients with periodontitis have a higher risk of cardiovascular diseases, although a causal relationship between these conditions remains unclear. Arterial stiffness is considered a marker of arteriosclerosis and a risk factor for cardiovascular diseases. A systematic review of the literature on ...

    journal_title:Journal of clinical periodontology

    pub_type: 杂志文章,meta分析,评审

    doi:10.1111/jcpe.12467

    authors: Schmitt A,Carra MC,Boutouyrie P,Bouchard P

    更新日期:2015-11-01 00:00:00

  • Post-extraction dimensional changes: A systematic review and meta-analysis.

    abstract:AIM:To analyse the evidence pertaining to post-extraction dimensional changes in the alveolar ridge after unassisted socket healing. MATERIALS AND METHODS:The protocol of this PRISMA-compliant systematic review (SRs) was registered in PROSPERO (CRD42020178857). A literature search to identify studies that fulfilled th...

    journal_title:Journal of clinical periodontology

    pub_type: 杂志文章,评审

    doi:10.1111/jcpe.13390

    authors: Couso-Queiruga E,Stuhr S,Tattan M,Chambrone L,Avila-Ortiz G

    更新日期:2021-01-01 00:00:00

  • A biomechanical assessment of the relation between the oral implant stability at insertion and subjective bone quality assessment.

    abstract:AIM:The study was set to evaluate the validity of subjective jaw bone quality assessment. MATERIALS AND METHODS:A total of 298 patients (198 females, mean age 56.4) were treated with oral implants at the Periodontology Department at the University Hospital of KUL. A total of 761 TiUnite implants have been installed. S...

    journal_title:Journal of clinical periodontology

    pub_type: 杂志文章

    doi:10.1111/j.1600-051X.2007.01047.x

    authors: Alsaadi G,Quirynen M,Michiels K,Jacobs R,van Steenberghe D

    更新日期:2007-04-01 00:00:00

  • Treatment of localized aggressive periodontitis alters local host immunoinflammatory profiles: A long-term evaluation.

    abstract:AIM:To evaluate the local immunoinflammatory profiles in localized aggressive periodontitis patients (LAP) before and after periodontal treatment and maintenance. METHODS:Sixty-six African-Americans with LAP (7-21 years old) were included. After periodontal examination, all patients received periodontal treatment with...

    journal_title:Journal of clinical periodontology

    pub_type: 杂志文章

    doi:10.1111/jcpe.13404

    authors: Branco-de-Almeida LS,Cruz-Almeida Y,Gonzalez-Marrero Y,Kudsi R,de Oliveira ICV,Dolia B,Huang H,Aukhil I,Harrison P,Shaddox LM

    更新日期:2021-02-01 00:00:00