Acute toxicological effects in rats treated with a mixture of commercially formulated products containing methyl parathion and permethrin.

Abstract:

:The study examined the interactions between a commercial formulation of methyl parathion (CF-MP) and a commercially formulated product of permethrin (CF-PMT) in male rats. The acute toxicity (LD50 values) and brain cholinesterase activity were investigated as toxicological endpoints. Results indicated that CF-MP modified the acute toxicity of CF-PMT. When animals were treated with a mixture, the addition of 380 mg/kg of CF-MP reduced the LD50 of CF-PMT by only 9.0%; however, when rats received CF-MP at 464 mg/kg, the LD50 of CF-PMT was reduced by 37% (P < 0.001). Also, CF-PMT decreased the CF-MP-induced inhibition of cholinesterase activity by 50% (P < 0.05). It was interesting to observe that xylene, which is the most abundant component in the vehicle of both formulations, had no effect on the CF-MP-induced inhibition of the cholinesterase activity. There was no relation between lethality and the inhibition of the brain cholinesterase activity in rats treated with mixtures containing CF-MP+CF-PMT or with either commercially formulated product alone. Considering the increased toxicity observed in rats treated with CF-PMT+CF-MP, it would be advisable to investigate further the interactions between both pesticides.

journal_name

Ecotoxicol Environ Saf

authors

Ortiz D,Yáñez L,Gómez H,Martínez-Salazar JA,Díaz-Barriga F

doi

10.1006/eesa.1995.1096

subject

Has Abstract

pub_date

1995-11-01 00:00:00

pages

154-8

issue

2

eissn

0147-6513

issn

1090-2414

pii

S0147651385710962

journal_volume

32

pub_type

杂志文章
  • The effect of biotic and abiotic environmental factors on Pd(II) adsorption and reduction by Bacillus wiedmannii MSM.

    abstract::In this paper, we found a bacteria (Bacillus wiedmannii MSM) that could not only culture quickly under aerobic condition, but also can biological reduction of Pd (II) under both aerobic and anaerobic conditions. For reducing Pd (II) by Bacillus wiedmannii MSM, the best electron donor was sodium formate and the best gr...

    journal_title:Ecotoxicology and environmental safety

    pub_type: 杂志文章

    doi:10.1016/j.ecoenv.2018.07.043

    authors: Chen Y,Chen Y,Wu J,Zhang J

    更新日期:2018-10-30 00:00:00

  • Effects of heavy metal terbium on contents of cytosolic nutrient elements in horseradish cell.

    abstract::The wide application of rare earth elements (REEs) has led to the accumulation of REEs in soil and plant. Thereby, the effect of Tb(3+) on the contents of cytosolic nutrient elements in horseradish was investigated with the synchronous detection technique of scanning electron microscope and energy dispersive X-ray spe...

    journal_title:Ecotoxicology and environmental safety

    pub_type: 杂志文章

    doi:10.1016/j.ecoenv.2010.03.010

    authors: Wang L,Zhou Q,Huang X

    更新日期:2010-07-01 00:00:00

  • Root system architecture, physiological analysis and dynamic transcriptomics unravel the drought-responsive traits in rice genotypes.

    abstract::Drought is the major abiotic factors that limit crop productivity worldwide. To withstand stress conditions, plants alter numerous mechanisms for adaption and tolerance. Therefore, in the present study, 106 rice varieties were screened for drought tolerance phenotype via exposing different concentrations of polyethyle...

    journal_title:Ecotoxicology and environmental safety

    pub_type: 杂志文章

    doi:10.1016/j.ecoenv.2020.111252

    authors: Tiwari P,Srivastava D,Chauhan AS,Indoliya Y,Singh PK,Tiwari S,Fatima T,Mishra SK,Dwivedi S,Agarwal L,Singh PC,Asif MH,Tripathi RD,Shirke PA,Chakrabarty D,Chauhan PS,Nautiyal CS

    更新日期:2021-01-01 00:00:00

  • Antifouling and toxic properties of the bioactive metabolites from the seagrasses Syringodium isoetifolium and Cymodocea serrulata.

    abstract::The present study documents the antifouling and toxic properties of seagrasses Syringodium isoetifolium and Cymodocea serrulata. For that, the seagrasses S. isoetifolium and C. serrulata were extracted individually using organic solvents viz. dichloromethane, acetone and methanol. Amongst the extracts, the maximum ant...

    journal_title:Ecotoxicology and environmental safety

    pub_type: 杂志文章

    doi:10.1016/j.ecoenv.2014.02.009

    authors: Iyapparaj P,Revathi P,Ramasubburayan R,Prakash S,Palavesam A,Immanuel G,Anantharaman P,Sautreau A,Hellio C

    更新日期:2014-05-01 00:00:00

  • Bioavailability indicators of inhaled cadmium compounds.

    abstract::In a thirty-day inhalation study male Wistar rats were continuously exposed to submicron aerosols of three different cadmium compounds. The cadmium chloride (CdCl2) and cadmium oxide (CdO) aerosol concentrations were 0.1 mg/m3 Cd. Because of its lower solubility the cadmium sulfide (CdS) level was 1 mg/m3 Cd. For CdCl...

    journal_title:Ecotoxicology and environmental safety

    pub_type: 杂志文章

    doi:10.1016/0147-6513(86)90100-4

    authors: Glaser U,Klöppel H,Hochrainer D

    更新日期:1986-06-01 00:00:00

  • Influence of nine antibiotics on key secondary metabolites and physiological characteristics in Triticum aestivum: leaf volatiles as a promising new tool to assess toxicity.

    abstract::Extensive worldwide use of antibiotics has resulted in significant diffuse pollution of antibiotics in environment, but understanding the effects of many important antibiotics on plant physiological activity is still limited, especially at realistic environmental concentrations of antibiotics. To gain insight into inf...

    journal_title:Ecotoxicology and environmental safety

    pub_type: 杂志文章

    doi:10.1016/j.ecoenv.2012.09.019

    authors: Opriş O,Copaciu F,Loredana Soran M,Ristoiu D,Niinemets U,Copolovici L

    更新日期:2013-01-01 00:00:00

  • Effects of continuous acute and intermittent exposure on the tolerance of juvenile yellow catfish (Pelteobagrus fulvidraco) in total dissolved gas supersaturated water.

    abstract::Total dissolved gas (TDG) supersaturation generated by discharged flood water may cause the death of fish downstream of dams and severely threaten their survival during the flood season. No study has performed to investigate the effects of TDG on fish dwelling in shallows in China. Furthermore, varied TDG levels are c...

    journal_title:Ecotoxicology and environmental safety

    pub_type: 杂志文章

    doi:10.1016/j.ecoenv.2020.110855

    authors: Cao C,Deng Y,Yin Q,Li N,Liu X,Shi H,Yang Y,Xu L

    更新日期:2020-09-15 00:00:00

  • Growth, reproduction and biochemical toxicity of chlorantraniliprole in soil on earthworms (Eisenia fetida).

    abstract::Diamide insecticides have become the fourth most commonly used insecticide class in the world. Chlorantraniliprole (CAP) is a first-generation diamide insecticide with broad application potential. In this experiment, the eco-toxicity of CAP in soil at 0.1, 1.0, 5.0 and 10.0mg/kg on earthworms (Eisenia fetida) was eval...

    journal_title:Ecotoxicology and environmental safety

    pub_type: 杂志文章

    doi:10.1016/j.ecoenv.2017.12.010

    authors: Liu T,Wang X,Chen D,Li Y,Wang F

    更新日期:2018-04-15 00:00:00

  • Acute toxicity of lead on tolerance, oxygen consumption, ammonia-N excretion, and metal accumulation in Penaeus indicus postlarvae.

    abstract::The estuaries and backwaters that are the potential breeding grounds of penaeid shrimps are subject to heavy metal pollution through industrial effluents and domestic sewage. In the present investigation, laboratory experiments were conducted to study the acute toxicity of lead on tolerance, oxygen consumption, ammoni...

    journal_title:Ecotoxicology and environmental safety

    pub_type: 杂志文章

    doi:10.1006/eesa.2000.2019

    authors: Chinni S,Khan RN,Yallapragada PR

    更新日期:2002-02-01 00:00:00

  • Maleic acid assisted improvement of metal chelation and antioxidant metabolism confers chromium tolerance in Brassica juncea L.

    abstract::Chromium (Cr) is a highly toxic environmental pollutant that negatively affects plant growth and development. Thus, remediating Cr from soil or increasing plant tolerance against Cr stress is urgent. Organic acids are recognized as agents of phytoremediation and as exogenous protectants, but using maleic acid (MA) to ...

    journal_title:Ecotoxicology and environmental safety

    pub_type: 杂志文章

    doi:10.1016/j.ecoenv.2017.06.010

    authors: Mahmud JA,Hasanuzzaman M,Nahar K,Rahman A,Hossain MS,Fujita M

    更新日期:2017-10-01 00:00:00

  • Prediction of heavy metal behavior in soil by means of simple field tests.

    abstract::Binding and retention against uptake by plants, and groundwater pollution of the metal ions Cd, Mn, Ni, Co, Zn, Cu, Cr(III), Pb, Hg, Fe(III), and Al by soils in relation to pH, redox potential, texture, organic matter, and iron oxide contents can be diagnosed in the form of rough relative values with simple field meth...

    journal_title:Ecotoxicology and environmental safety

    pub_type: 杂志文章

    doi:10.1016/0147-6513(91)90056-u

    authors: Blume HP,Brümmer G

    更新日期:1991-10-01 00:00:00

  • Environmental resistome risks of wastewaters and aquatic environments deciphered by shotgun metagenomic assembly.

    abstract::In this paper, we deciphered the core resistome disseminating from hospital wastewater to the aquatic environment by characterising the resistome, plasmidome, mobilome and virulome using metagenomic analysis. This study also elucidated different environmental resistome risks using shotgun-metagenomic assembly. The res...

    journal_title:Ecotoxicology and environmental safety

    pub_type: 杂志文章

    doi:10.1016/j.ecoenv.2020.110612

    authors: Ekwanzala MD,Dewar JB,Momba MNB

    更新日期:2020-07-01 00:00:00

  • Differential gene expression analysis of benzo(a)pyrene toxicity in the clam, Ruditapes philippinarum.

    abstract::Polycyclic aromatic hydrocarbons (PAHs) are known for their carcinogenic, teratogenic and mutagenic properties. Benzo(a)pyrene (BaP) possesses the greatest carcinogenic potential among the various PAHs. In this study, digital gene expression (DGE) was performed to investigate the digestive gland transcriptome profile ...

    journal_title:Ecotoxicology and environmental safety

    pub_type: 杂志文章

    doi:10.1016/j.ecoenv.2015.02.007

    authors: Liu T,Pan L,Jin Q,Cai Y

    更新日期:2015-05-01 00:00:00

  • Photochemistry and proteomics of mulberry (Morus alba L.) seedlings under NaCl and NaHCO3 stress.

    abstract::In order to explore the response and adaptation mechanisms of photosynthesis of the leaves of mulberry (Morus alba L.) seedlings to saline-alkali stress. Photosynthetic activity, and the response of related proteomics of M. alba seedling leaves under NaCl and NaHCO3 stress were studied by using chlorophyll fluorescenc...

    journal_title:Ecotoxicology and environmental safety

    pub_type: 杂志文章

    doi:10.1016/j.ecoenv.2019.109624

    authors: Hui-Hui Z,Guang-Liang S,Jie-Yu S,Xin L,Ma-Bo L,Liang M,Nan X,Guang-Yu S

    更新日期:2019-11-30 00:00:00

  • Perfluorinated chemicals in blood of residents in Wenzhou, China.

    abstract::Perfluorinated compounds (PFCs) are persistent organic pollutants ubiquitously distributed in the environment and human populations. Here we report PFC concentrations in the residents of Wenzhou City, which is characterized as the 'Footwear Capital' of China. Specifically, fifty serum samples collected from workers in...

    journal_title:Ecotoxicology and environmental safety

    pub_type: 杂志文章

    doi:10.1016/j.ecoenv.2011.04.027

    authors: Zhang W,Lin Z,Hu M,Wang X,Lian Q,Lin K,Dong Q,Huang C

    更新日期:2011-09-01 00:00:00

  • Exogenous phosphite application alleviates the adverse effects of heat stress and improves thermotolerance of potato (Solanum tuberosum L.) seedlings.

    abstract::Phosphite (Phi), an analog of phosphate (Pi) anion, is emerging as a potential biostimulator, fungicide and insecticide. Here, we reported that Phi also significantly enhanced thermotolerance in potatoes under heat stress. Potato plants with and without Phi pretreatment were exposed to heat stress and their heat toler...

    journal_title:Ecotoxicology and environmental safety

    pub_type: 杂志文章

    doi:10.1016/j.ecoenv.2019.110048

    authors: Xi Y,Han X,Zhang Z,Joshi J,Borza T,Mohammad Aqa M,Zhang B,Yuan H,Wang-Pruski G

    更新日期:2020-03-01 00:00:00

  • Copper induces hepatocyte autophagy via the mammalian targets of the rapamycin signaling pathway in mice.

    abstract::Although copper is among the indispensable trace elements in animal physiological processes, it exerts toxicity upon over-exposure. The present study aimed to investigate hepatocyte autophagy induced by CuSO4 and its potential mechanism. A total of 240 ICR mice (four-week-old, 120 males and 120 females) were randomly ...

    journal_title:Ecotoxicology and environmental safety

    pub_type: 杂志文章

    doi:10.1016/j.ecoenv.2020.111656

    authors: Liu H,Deng H,Cui H,Jian Z,Guo H,Fang J,Zuo Z,Deng J,Li Y,Wang X,Zhao L

    更新日期:2021-01-15 00:00:00

  • Activities of cellulase and amylase in soils as influenced by insecticide interactions.

    abstract::Interaction effects of the insecticides monocrotophos and quinalphos (organophosphates), and cypermethrin (pyrethroid), on microbial activities in two agricultural soils-black vertisol soil and red alfinsol soil were tested for 30 days under laboratory conditions. Individual application of the three insecticides at 5,...

    journal_title:Ecotoxicology and environmental safety

    pub_type: 杂志文章

    doi:10.1016/j.ecoenv.2006.11.011

    authors: Gundi VA,Viswanath B,Chandra MS,Kumar VN,Reddy BR

    更新日期:2007-10-01 00:00:00

  • Chemical and toxicological evaluation of underground coal gasification (UCG) effluents. The coal rank effect.

    abstract::The effect of coal rank on the composition and toxicity of water effluents resulting from two underground coal gasification experiments with distinct coal samples (lignite and hard coal) was investigated. A broad range of organic and inorganic parameters was determined in the sampled condensates. The physicochemical t...

    journal_title:Ecotoxicology and environmental safety

    pub_type: 杂志文章

    doi:10.1016/j.ecoenv.2014.10.038

    authors: Kapusta K,Stańczyk K

    更新日期:2015-02-01 00:00:00

  • Pigments as biomarkers of exposure to the vineyard herbicide flazasulfuron in freshwater algae.

    abstract::Weed control in Champagne vineyards has long relied on the use of diuron and substituted triazines; these compounds are now being replaced by flazasulfuron, a sulfonylurea that is used at a much lower dosage. The vineyards of Champagne are planted on steep slopes and runoff is important, and even though low doses of t...

    journal_title:Ecotoxicology and environmental safety

    pub_type: 杂志文章

    doi:10.1016/s0147-6513(02)00064-7

    authors: Couderchet M,Vernet G

    更新日期:2003-07-01 00:00:00

  • Reduction of hexavalent chromium by the earthworm Eisenia foetida (Savigny).

    abstract::Several metabolic systems in Eisenia foetida competent to achieve an intracellular Cr(VI) reduction are described. Evidence that earthworms act as effective scavengers of hexavalent chromium from the environment is also provided. Results suggest that E. foetida may play an important role during occasional Cr(VI) pollu...

    journal_title:Ecotoxicology and environmental safety

    pub_type: 杂志文章

    doi:10.1016/0147-6513(91)90011-d

    authors: Arillo A,Melodia F

    更新日期:1991-02-01 00:00:00

  • Effects of electromagnetic fields on parthenogenic eggs of Daphnia magna Straus.

    abstract::Developing parthenogenetic eggs of Daphnia magna were used as a test-system to evaluate the effect of a number of low-frequency electromagnetic fields (EMF) of 75microT density. Two blocks of EMF acting frequencies were found in the studied series-45, 110, and 175Hz, and 435 and 500Hz. Developing parthenogenetic eggs ...

    journal_title:Ecotoxicology and environmental safety

    pub_type: 杂志文章

    doi:10.1016/j.ecoenv.2009.03.005

    authors: Krylov VV

    更新日期:2010-01-01 00:00:00

  • Acute toxicity of locust insecticides to two indigenous invertebrates from Sahelian temporary ponds.

    abstract::During desert locust plagues large amounts of insecticides are used for control operations. Drift from these treatments and accidental overspraying may contaminate small surface waters such as temporary ponds. The present study describes methods for static acute toxicity tests with two abundant organisms that occur in...

    journal_title:Ecotoxicology and environmental safety

    pub_type: 杂志文章

    doi:10.1006/eesa.2000.1995

    authors: Lahr J,Badji A,Marquenie S,Schuiling E,Ndour KB,Diallo AO,Everts JW

    更新日期:2001-01-01 00:00:00

  • Cell density dependence of Microcystis aeruginosa responses to copper algaecide concentrations: Implications for microcystin-LR release.

    abstract::Along with mechanistic models, predictions of exposure-response relationships for copper are often derived from laboratory toxicity experiments with standardized experimental exposures and conditions. For predictions of copper toxicity to algae, cell density is a critical factor often overlooked. For pulse exposures o...

    journal_title:Ecotoxicology and environmental safety

    pub_type: 杂志文章

    doi:10.1016/j.ecoenv.2017.08.010

    authors: Kinley CM,Iwinski KJ,Hendrikse M,Geer TD,Rodgers JH Jr

    更新日期:2017-11-01 00:00:00

  • Modelling algae-duckweed interaction under chemical pressure within a laboratory microcosm.

    abstract::Contaminant effects on species are generally assessed with single-species bioassays. As a consequence, interactions between species that occur in ecosystems are not taken into account. To investigate the effects of contaminants on interacting species dynamics, our study describes the functioning of a 2-L laboratory mi...

    journal_title:Ecotoxicology and environmental safety

    pub_type: 杂志文章

    doi:10.1016/j.ecoenv.2016.02.008

    authors: Lamonica D,Clément B,Charles S,Lopes C

    更新日期:2016-06-01 00:00:00

  • Mobility and potential bioavailability of antimony in contaminated soils: Short-term impact on microbial community and soil biochemical functioning.

    abstract::Antimony (Sb) and its compounds are emerging priority pollutants which pose a serious threat to the environment. The aim of this study was to evaluate the short-term fate of antimonate added to different soils (S1 and S2) with respect to its mobility and impact on soil microbial communities and soil biochemical functi...

    journal_title:Ecotoxicology and environmental safety

    pub_type: 杂志文章

    doi:10.1016/j.ecoenv.2020.110576

    authors: Diquattro S,Garau G,Mangia NP,Drigo B,Lombi E,Vasileiadis S,Castaldi P

    更新日期:2020-06-15 00:00:00

  • Degradation of Jatropha curcas phorbol esters derived from Jatropha oil cake and their tumor-promoting activity.

    abstract::Large amount of oil cake is generated during biodiesel production from Jatropha seeds. Although Jatropha oil cake is rich in plant nutrients, presence of toxic phorbol esters restricts the usage of oil cake as a fertilizer. The objective of this study is to evaluate the components and tumor promoting activity of phorb...

    journal_title:Ecotoxicology and environmental safety

    pub_type: 杂志文章

    doi:10.1016/j.ecoenv.2014.07.009

    authors: Nakao M,Hasegawa G,Yasuhara T,Ishihara Y

    更新日期:2015-04-01 00:00:00

  • Age differential response of Hyalella curvispina to a cadmium pulse: influence of sediment particle size.

    abstract::In Argentina periurban streams frequently receive agricultural, livestock and industrial discharges. Heavy metals have been found in the water column and sediments of numerous water bodies of the pampean region, at levels above the limits established for aquatic life protection. This study aimed to evaluate the effect...

    journal_title:Ecotoxicology and environmental safety

    pub_type: 杂志文章

    doi:10.1016/j.ecoenv.2012.03.017

    authors: García ME,Rodrígues Capítulo A,Ferrari L

    更新日期:2012-06-01 00:00:00

  • Different lethal treatments induce changes in piperidine (1,1'-(1,2-ethanediyl)bis-) in the epidermal compounds of red imported fire ants and affect corpse-removal behavior.

    abstract::Corpse-removal behavior of the red imported fire ant (RIFA) and the effects of lethal substances on RIFA signal communication were investigated in this study. The RIFA corpses, obtained through freezing, ether, 0.25 mg/L thiamethoxam, and starvation to death treatments, and naturally dead red fire ants were subjected ...

    journal_title:Ecotoxicology and environmental safety

    pub_type: 杂志文章

    doi:10.1016/j.ecoenv.2020.110391

    authors: Qin D,Zhang P,Zhou Y,Zheng Q,Hou R,Liu B,Chen J,Zhang Z

    更新日期:2020-05-01 00:00:00

  • Effects of the naturally-occurring contaminant microcystins on the Azolla filiculoides-Anabaena azollae symbiosis.

    abstract::Harmful algal blooms (HABs) contaminate aquatic ecosystems and are responsible for animal poisoning worldwide. We conducted a toxicity test with the aquatic fern and the biofertilizer, Azolla filiculoides. The sporophytes were exposed to three concentrations (0.01, 0.1 and 1μgmL(-1)) of a microcystin (MC) cyanobacteri...

    journal_title:Ecotoxicology and environmental safety

    pub_type: 杂志文章

    doi:10.1016/j.ecoenv.2015.04.008

    authors: Pereira AL,Monteiro B,Azevedo J,Campos A,Osório H,Vasconcelos V

    更新日期:2015-08-01 00:00:00