Treatment of terminal cancer pain in France: a questionnaire study.

abstract：:The effects of cognitive and competing sensory processing tasks on pain perception and as a function of time are only partially understood. To study these effects, we compared the simultaneous effects of noxious heat stimulation (HS), auditory stimulation (AS) (sinusoidally modulated speech-like signal, SMSLS), and a ...

journal_title：Pain

authors： Pud D,Sapir S

更新日期：2006-01-01 00:00:00

abstract：:Chronic neuropathic pain is associated with long-term changes at multiple levels of the neuroaxis, including in the brain, where electrical stimulation has been used to manage severe pain conditions. However, the clinical outcome of deep brain stimulation is often mixed, and the mechanisms are poorly understood. By me...

journal_title：Pain

authors： Iwata M,LeBlanc BW,Kadasi LM,Zerah ML,Cosgrove RG,Saab CY

更新日期：2011-11-01 00:00:00

abstract：:The associative network theory of memory [2] is outlined along with the concepts of mood congruity and state dependent learning. Two experiments are reported which investigate the occurrence of these effects where memory for pain is concerned. In experiment 1 the performance of 25 chronic pain patients was compared wi...

journal_title：Pain

authors： Pearce SA,Isherwood S,Hrouda D,Richardson PH,Erskine A,Skinner J

更新日期：1990-11-01 00:00:00

abstract：:A growing body of literature suggests that the experience of clinical pain differs across ethnocultural groups. Additionally, some evidence indicates greater sensitivity to experimentally induced pain among African Americans; however, most studies have included only one pain modality. This study examined ethnic differ...

journal_title：Pain

authors： Campbell CM,Edwards RR,Fillingim RB

更新日期：2005-01-01 00:00:00

abstract：:Oxytocin (OT), known for its neurohormonal effects around birth, has recently been suggested for being a critical determinant in neurodevelopmental disorders. This hypothalamic neuropeptide exerts a potent analgesic effect through an action on the nociceptive system. This endogenous control of pain has an important ad...

journal_title：Pain

authors： Melchior M,Juif PE,Gazzo G,Petit-Demoulière N,Chavant V,Lacaud A,Goumon Y,Charlet A,Lelièvre V,Poisbeau P

更新日期：2018-12-01 00:00:00

abstract：:Neuropathic pain can be a predictor of severe emotional distress, up to full-blown depressive states. In these patients, it is important to move beyond the sole treatment of pain, to recognize depressive symptoms, and to ultimately improve the quality of life. We systematically searched for published and unpublished c...

journal_title：Pain

authors： Caruso R,Ostuzzi G,Turrini G,Ballette F,Recla E,Dall'Olio R,Croce E,Casoni B,Grassi L,Barbui C

更新日期：2019-10-01 00:00:00

abstract：:The role of 5-hydroxytryptamine (5-HT)(4), 5-HT(6), and 5-HT(7) receptors in formalin-induced secondary allodynia and hyperalgesia in rats was assessed. Formalin produced acute nociceptive behaviors (flinching and licking/lifting) followed by long-term secondary mechanical allodynia and hyperalgesia. Pretreatment (-10...

journal_title：Pain

authors： Godínez-Chaparro B,Barragán-Iglesias P,Castañeda-Corral G,Rocha-González HI,Granados-Soto V

更新日期：2011-03-01 00:00:00

abstract：:The synaptic vesicle protein synapsin II plays an important role in the regulation of neurotransmitter release and synaptic plasticity. Here, we investigated its involvement in the synaptic transmission of nociceptive signals in the spinal cord and the development of pain hypersensitivity. We show that synapsin II is ...

journal_title：Pain

authors： Schmidtko A,Del Turco D,Coste O,Ehnert C,Niederberger E,Ruth P,Deller T,Geisslinger G,Tegeder I

更新日期：2005-05-01 00:00:00

abstract：:We report the case of bilateral hand swelling following acupuncture therapy for chronic low back pain. Despite thorough history, examination and laboratory testing no systemic cause for the swelling could be elicited. This case highlights the incomplete knowledge of acupuncture mechanisms and that limited acupuncture ...

journal_title：Pain

authors： McCartney CJ,Herriot R,Chambers WA

更新日期：2000-02-01 00:00:00

abstract：:The N-methyl-D-aspartic acid (NMDA) receptor antagonist D, L-2-amino-5-phosphonopentanoic acid (AP5) caused a stronger inhibition of wind-up in single wide dynamic range (WDR) neurons after carrageenan inflammation compared with control neurons without inflammation in the receptive field. This indicates that even a sh...

journal_title：Pain

authors： Svendsen F,Rygh LJ,Hole K,Tjølsen A

更新日期：1999-12-01 00:00:00

abstract：:Patients with schizophrenia report reduced pain sensitivity in clinical studies, but experimental studies are required to establish pain sensitivity as a potential endophenotype. We conducted a systematic review of electronic databases from database inception until April 15, 2015, including experimental studies invest...

journal_title：Pain

authors： Stubbs B,Thompson T,Acaster S,Vancampfort D,Gaughran F,Correll CU

更新日期：2015-11-01 00:00:00

abstract：:Clinical observations and recent studies suggest that arthritis patients vary considerably in their involvement in self-management efforts. In the literature on health promotion, there is growing recognition that patients may be at different stages of change with respect to the adoption of self-management strategies. ...

journal_title：Pain

authors： Keefe FJ,Lefebvre JC,Kerns RD,Rosenberg R,Beaupre P,Prochaska J,Prochaska JO,Caldwell DS

更新日期：2000-09-01 00:00:00

abstract：:Movement is changed in pain, but the mechanisms remain unclear. Key questions are unresolved such as whether activation can be inhomogeneously distributed within a muscle in a manner that is specific to the location of noxious input. This study addressed this question using high-density electromyography (EMG) to study...

journal_title：Pain

authors： Gallina A,Salomoni SE,Hall LM,Tucker K,Garland SJ,Hodges PW

更新日期：2018-11-01 00:00:00

abstract：:Toll-like receptor 7 (TLR7) is associated with the pathophysiology of systemic lupus erythematosus and Sjögren syndrome, well-known diseases accompanying interstitial cystitis (IC). We studied TLR7 expression in the bladder of patients with Hunner-type IC (HIC) and its functional roles in bladder inflammation and noci...

journal_title：Pain

authors： Ichihara K,Aizawa N,Akiyama Y,Kamei J,Masumori N,Andersson KE,Homma Y,Igawa Y

更新日期：2017-08-01 00:00:00

abstract：:Treatment of neuropathic pain is a major clinical challenge that has been met with minimal success. After peripheral nerve injury, a decrease in the expression of the K-Cl cotransporter KCC2, a major neuronal Cl(-) extruder, leads to pathologic alterations in GABA(A) and glycine receptor function in the spinal cord. T...

journal_title：Pain

authors： Asiedu M,Ossipov MH,Kaila K,Price TJ

更新日期：2010-02-01 00:00:00

abstract：:Orexins are neuropeptides that are mostly expressed in the posterior and lateral hypothalamus, and related to the central control of appetite, arousal, and antinociception. Orexin neurons projected to the tuberomammillary nucleus and orexins may release histamine from the histamine neurons in this nucleus. Histamine i...

journal_title：Pain

authors： Mobarakeh JI,Takahashi K,Sakurada S,Nishino S,Watanabe H,Kato M,Naghdi N,Yanai K

更新日期：2005-11-01 00:00:00

abstract：:TRPV1 is expressed in a subpopulation of myelinated Aδ and unmyelinated C-fibers. TRPV1+ fibers are essential for the transmission of nociceptive thermal stimuli and for the establishment and maintenance of inflammatory hyperalgesia. We have previously shown that high-power, short-duration pulses from an infrared diod...

journal_title：Pain

authors： Mitchell K,Lebovitz EE,Keller JM,Mannes AJ,Nemenov MI,Iadarola MJ

更新日期：2014-04-01 00:00:00

abstract：:Pain behaviors are shaped by social demands and learning processes, and chronic pain has been previously suggested to affect their meaning. In this study, we combined functional magnetic resonance imaging with in-scanner video recording during thermal pain stimulations and use multilevel mediation analyses to study th...

journal_title：Pain

authors： Vachon-Presseau E,Roy M,Woo CW,Kunz M,Martel MO,Sullivan MJ,Jackson PL,Wager TD,Rainville P

更新日期：2016-08-01 00:00:00

abstract：:Previous research implicates an endogenous central pain inhibitory mechanism in opiate analgesia, analgesia produced by focal electrical stimulation of the brain, and acupuncture analgesia. This investigation evaluates the possibility that analgesia produced by hypnosis is also mediated by such a mechanism. Results su...

journal_title：Pain

authors： Barber J,Mayer D

更新日期：1977-10-01 00:00:00

abstract：:This article reports on a study that examines the influence of task-related factors on nurses' pain assessments and decision regarding interventions. In an experimental design pediatric nurses (n = 202), were exposed to different cases, each case being a combination of a vignette and a videotape. For every case subjec...

journal_title：Pain

authors： Hamers JPH,Abu-Saad HH,van den Hout MA,Halfens RJG,Kester ADM

更新日期：1996-04-01 00:00:00

abstract：:This study investigated the effects of a single administration of 6-(4-methoxyphenyl)-5-methyl-3-pyridinyl-4-isoxazolo[4,5-c]pyridin-4(5H)-one (MMPIP), a negative allosteric modulator (NAM) of metabotropic glutamate receptor 7 (mGluR7), on pain and on affective and cognitive behavior in neuropathic mice. The activity ...

journal_title：Pain

authors： Palazzo E,Romano R,Luongo L,Boccella S,De Gregorio D,Giordano ME,Rossi F,Marabese I,Scafuro MA,de Novellis V,Maione S

更新日期：2015-06-01 00:00:00

abstract：:This study focuses on changes in adrenergic sensitivity in untransected sensory axons that innervate an area of skin made neuropathic by transection of neighboring nerves. The segmental nerve injury model is favorable for this since all axons in the L5 and L6 nerves are transected whereas the L4 axons are intact. Earl...

journal_title：Pain

authors： Moon DE,Lee DH,Han HC,Xie J,Coggeshall RE,Chung JM

更新日期：1999-04-01 00:00:00

abstract：:Phantom urinary phenomena are a relatively rare disease entity. Literature search has revealed only one case following cystectomy, seven cases following spinal cord injury and several other cases in hemodialysis patients. This report presents a case of painful phantom bladder following cystectomy for chronic kidney an...

journal_title：Pain

authors： Brena SF,Sammons EE

更新日期：1979-10-01 00:00:00

abstract：:A large body of evidence indicates that nitric oxide (NO)/cGMP signaling essentially contributes to the processing of chronic pain. In general, NO-induced cGMP formation is catalyzed by 2 isoforms of guanylyl cyclase, NO-sensitive guanylyl cyclase 1 (NO-GC1) and 2 (NO-GC2). However, the specific functions of the 2 iso...

journal_title：Pain

authors： Petersen J,Mergia E,Kennel L,Drees O,Steubing RD,Real CI,Kallenborn-Gerhardt W,Lu R,Friebe A,Koesling D,Schmidtko A

更新日期：2019-03-01 00:00:00

abstract：:In a group of 30 subjects suffering from sympathetic reflex dystrophies of the limbs, the sympathetic ganglia of the affected side were blocked with a local anesthetic. Using an original method, we measured the cutaneous pain threshold before the block and at prefixed intervals after the block during a period of 2 day...

journal_title：Pain

authors： Procacci P,Francini F,Zoppi M,Maresca M

更新日期：1975-06-01 00:00:00

abstract：:The aim of the present study was to determine if acupuncture stimulation inhibits sympathetic nerve activity in humans. Multiunit efferent postganglionic sympathetic activity was recorded with a tungsten microelectrode inserted in a muscle fascicle of the peroneal nerve. Mean arterial pressure, heart rate and skin blo...

journal_title：Pain

authors： Knardahl S,Elam M,Olausson B,Wallin GB

更新日期：1998-03-01 00:00:00

abstract：:We investigated the question of how cultural and linguistic backgrounds affect relationships among ratings (reported by patients with metastatic cancer) of pain's interference with such functions as activity, mood, and sleep. Multidimensional scaling (MDS) was used to analyze ratings of pain interference from a sample...

journal_title：Pain

authors： Cleeland CS,Nakamura Y,Mendoza TR,Edwards KR,Douglas J,Serlin RC

更新日期：1996-10-01 00:00:00

abstract：:As part of a comprehensive study of the natural history of herpes zoster (HZ), 57 of 94 subjects in a cohort at elevated risk for post-herpetic neuralgia (PHN) consented to collection of 3-mm skin punch biopsies from affected, mirror-image, and distant control skin at baseline and followup visits. As cutaneous innerva...

journal_title：Pain

authors： Petersen KL,Rice FL,Farhadi M,Reda H,Rowbotham MC

更新日期：2010-07-01 00:00:00

abstract：:Chronic dry eye disease (DE) is associated with an unstable tear film and symptoms of ocular discomfort. The characteristics of symptoms suggest a key role for central neural processing; however, little is known about central neuroplasticity and DE. We used a model for tear deficient DE and assessed effects on eye bli...

journal_title：Pain

authors： Rahman M,Okamoto K,Thompson R,Katagiri A,Bereiter DA

更新日期：2015-05-01 00:00:00

abstract：:Our goal was to examine the association between mental health disorders (MHD) and subsequent risk of opioid use among commercially insured youth and adults (aged 14-64 years) with comorbid chronic noncancer pain (CNCP) conditions. We conducted a retrospective cohort study using IQVIA Health Plan Claims database from J...

journal_title：Pain

authors： Olopoenia A,Onukwugha E,Simoni-Wastila L,Camelo-Castillo W,Villalonga-Olives E,Gandhi AB,Slejko J

更新日期：2020-10-01 00:00:00