Polyamines and terminal deoxynucleotidyl transferase expression in KM 3 pre-B cell line during phorbol ester induced differentiation.

abstract：:It has been proposed that cyclical gene expression occurs at a large number of different times during the cell cycle. The existence of a large number of cycle-specific variations in mRNA and protein during the eukaryotic cell cycle raises the problem of how cell-cycle variations are regulated. This is the "infinite re...

journal_title：Cell biology international

authors： Cooper S,Shedden K,Vu-Phan D

更新日期：2009-01-01 00:00:00

abstract：:Neuroinflammation is closely related with the pathogenesis and progress of neurodegenerative diseases including Alzheimer's disease (AD). Loganin, an iridoid glycoside obtained from traditional Chinese medicine Cornus officinalis, has properties of inhibiting inflammation and improving memory. The present study was ai...

journal_title：Cell biology international

authors： Cui Y,Wang Y,Zhao D,Feng X,Zhang L,Liu C

更新日期：2018-12-01 00:00:00

abstract：:Mouse embryonic stem (ES) cells can be differentiated into neural lineage cells, but the differentiation efficiency remains low. This study revealed two important factors that influence the neural differentiation efficiency of mouse ES cells: the first is the quality of embryonic bodies (EBs); good quality of EBs cons...

journal_title：Cell biology international

authors： Zhou JM,Xing FY,Shi JJ,Fang ZF,Chen XJ,Chen F

更新日期：2008-09-01 00:00:00

abstract：:Umbilical cord blood (UCB) is a valuable source for hematopoietic progenitor cell therapy. Moreover, it contains another subset of non-hematopoietic population referred to as mesenchymal progenitor cells (MPCs), which can be ex vivo expanded and differentiated into osteoblasts, chondrocytes and adipocytes. In this stu...

journal_title：Cell biology international

authors： Chang YJ,Tseng CP,Hsu LF,Hsieh TB,Hwang SM

更新日期：2006-06-01 00:00:00

abstract：:MicroRNA molecules (miRNAs) play important roles in regulating cell behavior. The expression of certain miRNAs has been shown to be regulated by the androgen receptor (AR), which seems to have a critical role in the tumorigenic process of breast cancer. The differential expression of 84 miRNAs was first examined in th...

journal_title：Cell biology international

authors： Ahram M,Mustafa E,Zaza R,Abu Hammad S,Alhudhud M,Bawadi R,Zihlif M

更新日期：2017-12-01 00:00:00

abstract：:In the present study, we investigated the effects of tetramethylpyrazine (TMP) on hydrogen peroxide (H2O2)-induced apoptosis in PC12 cells. The apoptosis in H2O2-induced PC12 cells was accompanied by a decrease in Bcl-2/Bax protein ratio, release of cytochrome c to cytosol and the activation of caspase-3. TMP not only...

journal_title：Cell biology international

authors： Cheng XR,Zhang L,Hu JJ,Sun L,Du GH

更新日期：2007-05-01 00:00:00

abstract：:Triple-negative breast cancer (TNBC) is a highly heterogeneous disease. The aim of this study is to identify the diagnostic and poor prognostic signatures in TNBC by exploring the aberrant DNA methylation and gene expression. Differential expression and methylation analysis of the TNBC and paracancer samples from The ...

journal_title：Cell biology international

authors： Zhang X,Kang X,Jin L,Bai J,Zhang H,Liu W,Wang Z

更新日期：2020-10-01 00:00:00

abstract：:The low density lipoprotein receptor-related protein (alpha(2)MR/LRP) is a cell surface receptor which is present on most cells and tissues. We show that the 85 kDa subunit, containing the transmembrane region and cytoplasmic domain is phosphorylated in vivo. Comparison of the phosphorylation of the low density lipopr...

journal_title：Cell biology international

authors： Djordjevic JT,Waterkeyn JG,Hennessy KL,Stanley KK

更新日期：2000-01-01 00:00:00

abstract：:Mutations in the lamin A gene have been shown, among other defects, to give rise to Hutchinson-Gilford progeria syndrome (HGPS) and to atypical Werner syndrome (WS), both of which are progeroid disorders. Here, we have investigated well-characterized WS patient cell strains that are compound heterozygous for mutations...

journal_title：Cell biology international

authors： Adelfalk C,Scherthan H,Hirsch-Kauffmann M,Schweiger M

更新日期：2005-12-01 00:00:00

abstract：:Whether fructose (FRU), as the sole energy source, confers a metabolic advantage on cancer cells against noxious stimuli is unknown. The aim of this study was to evaluate the effects of low (11 mM), moderate (25 mM), and high (55 mM) FRU concentrations alone or in combination with rotenone (ROT) or doxorubicin (DOX) i...

journal_title：Cell biology international

authors： Diaz-Aguirre V,Velez-Pardo C,Jimenez-Del-Rio M

更新日期：2016-11-01 00:00:00

abstract：:Insulin-like growth factor-1 (IGF-1) is a positive regulator in proliferation and differentiation of skeletal muscle cells, while myostatin (MSTN) is a member of transforming growth factor beta superfamily that acts as a negative regulator of skeletal muscle mass. The present study was performed to detail whether a co...

journal_title：Cell biology international

authors： Miyake M,Hayashi S,Sato T,Taketa Y,Watanabe K,Hayashi S,Tanaka S,Ohwada S,Aso H,Yamaguchi T

更新日期：2007-10-01 00:00:00

abstract：:Investigation of the relative slowness with which trypsin detaches epithelial cells from their adhesions with a substratum suggests that the adherent surface of the cells is normally rather inaccessible to the enzyme. Trypsinisation of cells through a porous filter allowing access of the enzyme to the underside of the...

journal_title：Cell biology international

authors： Simpson K,McGrath M,Curtis A

更新日期：1993-03-01 00:00:00

abstract：:Emergence of resistance to chemotherapy and radiotherapy is a major obstacle for the successful treatment of MM (multiple myeloma). Prednisone, vincristine and melphalan are commonly used chemotherapeutic agents for the treatment of MM. In the current study, we examined the presence of possible cross-resistance betwee...

journal_title：Cell biology international

authors： Mutlu P,Baran Y,Ural AU,Avcu F,Dirican B,Beyzadeoglu M,Gündüz U

更新日期：2011-07-01 00:00:00

abstract：:Aphidicolin, a selective inhibitor of DNA polymerase, totally blocks DNA replication in the micronucleus but not in the macronucleus of Paramecium caudatum. The ciliates no longer divide and after 4 days the DNA content of the macronucleus has increased by 64%. Concomitantly the cell volume has increased by 53%. ...

journal_title：Cell biology international

authors： Sabaneyeva E,Tao W,Verbelen JP

更新日期：1999-01-01 00:00:00

abstract：:Prolapsus uteri in pelvic supportive disorders are common in elderly women, and their etiology remains unclear. We examined elastin-binding proteins (EBPs) and binding sites in cultured cardinal ligament fibroblasts derived from elderly patients with prolapsus uteri (HPLiF) and compared them with those from age-matche...

journal_title：Cell biology international

authors： Yamamoto M,Akazawa K,Aoyagi M,Yamamoto N,Yamamoto K

更新日期：2002-01-01 00:00:00

abstract：:The effect of an organochlorine pesticide benzene hexachloride (containing alpha, beta, gamma and delta isomers) on the phagocytic activity of the vegetative cells of Dictyostelium discoideum was investigated. Benzene hexachloride (BHC) at concentrations of 60 ppm and above inhibited the phagocytic activity as reveale...

journal_title：Cell biology international

authors： Gayatri R,Chatterjee S

更新日期：1993-03-01 00:00:00

abstract：:The Drosophila ovary provides an attractive model for studying the extrinsic or intrinsic factors that regulate the fate of germline stem cells (GSCs). Using this model, we identified a new role for Drosophila spaghetti (spag), encoding a homolog of human RNA polymerase II-associated protein 3 (RPAP3), in regulating t...

journal_title：Cell biology international

authors： Chen D,Tao X,Zhou L,Sun F,Sun M,Fang X

更新日期：2018-07-01 00:00:00

abstract：:Periodontitis is a chronic inflammatory disease that results in the destruction of periodontal soft tissue and the resorption of alveolar bone. Evidence indicates that in diabetic patients, hyperglycemia suppresses periodontal ligament stem cell (PDLSC) functions and leads to difficulties in periodontal repair. The pr...

journal_title：Cell biology international

authors： Luo H,Zhu W,Mo W,Liang M

更新日期：2020-12-01 00:00:00

abstract：:Cell therapy and regenerative medicine are potentially two of the most exciting aspects of the novel therapeutic methods currently under development. However, these treatments present a number of important biosafety issues, like the possible transmission of microorganisms to the recipients. The most common potential f...

journal_title：Cell biology international

authors： Cobo F,Cortés JL,Cabrera C,Nieto A,Concha A

更新日期：2007-09-01 00:00:00

abstract：:Immunocytochemical staining of citrulline-containing proteins, i.e. products of endogenous peptidylarginine deiminase (EC 3.5.3.15) reaction, has been performed by chemical modification of citrulline residues in situ, followed by probing with IgG specific to the modified residues. Rat spinal cords that had been preinc...

journal_title：Cell biology international

authors： Asaga H,Senshu T

更新日期：1993-05-01 00:00:00

abstract：:Resistance to radiotherapy and chemotherapy has been a major problem of conventional cancer therapies, which consequently leads to cancer relapse and cancer-related death. It is known that cancer stem cells (CSCs) play a key role in therapy resistance and CSC-based targeted therapies have been considered as a powerful...

journal_title：Cell biology international

authors： Johari B,Rahmati M,Nasehi L,Mortazavi Y,Faghfoori MH,Rezaeejam H

更新日期：2020-12-01 00:00:00

abstract：:The authors examined the growth response of cardinal ligamental fibroblasts derived from patients with prolapsus uteri (HPLiF) and compared it with the response of those from control subjects (HCLiF). The growth rate during the logarithmic growth phase was not different between HPLiF and HCLiF, while the cell density ...

journal_title：Cell biology international

authors： Yamamoto M,Aoyagi M,Akazawa K,Tajima S,Yamamoto K

更新日期：1998-01-01 00:00:00

abstract：:Transforming growth factor β1 (TGFβ1) is a negative regulator of hematopoiesis, and yet, it is frequently found at the active sites of hematopoiesis. Here, we show for the first time that bone marrow-derived mononuclear cells (BM MNCs) secrete TGFβ1 in response to erythropoietin (EPO). We further show that human bone ...

journal_title：Cell biology international

authors： Kale VP

更新日期：2020-11-01 00:00:00

abstract：:The aim of this study was to obtain membrane-bound alkaline phosphatase from osteoblastic-like cells of human alveolar bone. Cells were obtained by enzymatic digestion and maintained in primary culture in osteogenic medium until subconfluence. First passage cells were cultured in the same medium and at 7, 14, and 21 d...

journal_title：Cell biology international

authors： Simão AM,Beloti MM,Rosa AL,de Oliveira PT,Granjeiro JM,Pizauro JM,Ciancaglini P

更新日期：2007-11-01 00:00:00

abstract：:The diabetic milieu is believed to change the activity, or result in damage of podocytes-a key component of the glomerular filtration barrier and known to secrete matrix for glomerular basement membrane. This in turn contributes to diabetic nephropathy. However, how podocyte dysfunction is triggered in diabetic nephro...

journal_title：Cell biology international

authors： Liu Y,Long L,Yuan F,Liu F,Liu H,Peng Y,Sun L,Chen G

更新日期：2015-02-01 00:00:00

abstract：:A view is emerging that human amylin (HA) kills pancreatic islet beta-cells by apoptosis. This study strengthens this view by documenting time-dependent morphological and ultrastructural changes in 10 microm HA-treated cultured RINm5F islet beta-cells. Membrane blebbing and microvilli loss were the earliest detectable...

journal_title：Cell biology international

authors： Saafi EL,Konarkowska B,Zhang S,Kistler J,Cooper GJ

更新日期：2001-01-01 00:00:00

abstract：:Reactive oxygen species (ROS) act as signaling molecules to regulate various cell functions. Numerous studies have demonstrated ROS to be essential for the differentiation of adipocytes. Peroxiredoxins (Prxs) are a ubiquitous family of antioxidant enzymes in mammalian cells. Prx2 is present in the cytoplasm and cell m...

journal_title：Cell biology international

authors： Kim MH,Kim JY,Kim JH,Lee HS,Huh JW,Lee DS

更新日期：2020-10-01 00:00:00

abstract：:The mdx mouse has been used as an animal model for human Duchenne muscular dystrophy (DMD). Unlike DMD, skeletal muscles of mdx mice undergo successful regeneration and do not show extensive fibrosis and functional impairment. Growth factors have been proposed to be involved in muscle growth and regeneration. We compa...

journal_title：Cell biology international

authors： Chen G,Bressler BH,Quinn LS

更新日期：1994-04-01 00:00:00

abstract：:The action of theophylline on the uptake of alpha-aminoisobutyric acid (AIB; an indicator of anti-inflammatory potency) stimulated by the glucocorticoid, dexamethasone, in cultured rat fibroblast monolayers was evaluated. Theophylline alone (0.1 m m) did not show significant activity (3314+/-27 cpm) compared with the ...

journal_title：Cell biology international

authors： Xenos K,Kalogeromitros D,Markantonis SL,Katsambas A,Katsarou A

更新日期：1998-01-01 00:00:00

abstract：:Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) gains access to host cells by attaching to angiotensin-converting enzyme 2 (ACE2). Vitamin D (VitD) can upregulate ACE2 and has an antagonistic effect on Renin, which exerts a vasodilatation and anti-inflammatory effect against coronavirus disease (COVID-19)...

journal_title：Cell biology international

authors： Shojaeefar E,Malih N,Rezaei N

更新日期：2021-01-01 00:00:00