Echo-planar magnetic resonance imaging studies of frontal cortex activation during word generation in humans.

abstract：:Carbon can exist as isolated dumbbell, 1D chain, 2D plane, and 3D network in carbon solids or carbon-based compounds, which attributes to its rich chemical binding way, including sp-, sp(2)-, and sp(3)-hybridized bonds. sp(2)-hybridizing carbon always captures special attention due to its unique physical and chemical ...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Li YL,Luo W,Zeng Z,Lin HQ,Mao HK,Ahuja R

更新日期：2013-06-04 00:00:00

abstract：:Dictyostelium actin was shown to become phosphorylated on Tyr-53 late in the developmental cycle and when cells in the amoeboid stage are subjected to stress but the phosphorylated actin had not been purified and characterized. We have separated phosphorylated and unphosphorylated actin and shown that Tyr-53 phosphory...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Liu X,Shu S,Hong MS,Levine RL,Korn ED

更新日期：2006-09-12 00:00:00

abstract：:We study inverse statistical mechanics: how can one design a potential function so as to produce a specified ground state? In this article, we show that unexpectedly simple potential functions suffice for certain symmetrical configurations, and we apply techniques from coding and information theory to provide mathemat...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Cohn H,Kumar A

更新日期：2009-06-16 00:00:00

abstract：:Many current treatments for the reclamation of contaminated water sources are chemical-intensive, energy-intensive, and/or require posttreatment due to unwanted by-product formation. We demonstrate that through the integration of nanostructured materials, enzymatic catalysis, and iron-catalyzed free radical reactions ...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Lewis SR,Datta S,Gui M,Coker EL,Huggins FE,Daunert S,Bachas L,Bhattacharyya D

更新日期：2011-05-24 00:00:00

abstract：:The eyes of some aquatic animals form images through reflective optics. Shrimp, lobsters, crayfish, and prawns possess reflecting superposition compound eyes, composed of thousands of square-faceted eye units (ommatidia). Mirrors in the upper part of the eye (the distal mirror) reflect light collected from many ommati...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Palmer BA,Hirsch A,Brumfeld V,Aflalo ED,Pinkas I,Sagi A,Rosenne S,Oron D,Leiserowitz L,Kronik L,Weiner S,Addadi L

更新日期：2018-03-06 00:00:00

abstract：:The unique specificity of monoclonal antibodies (Ab) was combined with the cell-killing function of the cytolytic alternative pathway of complement. The functionally C3b-like glycoprotein of cobra venom was linked to a murine monoclonal Ab directed to a human melanoma-associated antigen by a disulfide bond, by using a...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Vogel CW,Müller-Eberhard HJ

更新日期：1981-12-01 00:00:00

abstract：:Mutations in Cu, Zn superoxide dismutase (SOD1) cause the neurodegenerative disease familial amyotrophic lateral sclerosis from an as-yet-unidentified toxic property(ies). Analysis in Saccharomyces cerevisiae of a broad range of human familial amyotrophic lateral sclerosis-linked SOD1 mutants (A4V, G37R, G41D, H46R, H...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Corson LB,Strain JJ,Culotta VC,Cleveland DW

更新日期：1998-05-26 00:00:00

abstract：:The blind Mexican cave tetra, Astyanax mexicanus, is a unique model system for the study of parallelism and the evolution of cave-adapted traits. Understanding the genetic basis for these traits has recently become feasible thanks to production of a genome-wide linkage map and quantitative trait association analyses. ...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Gross JB,Protas M,Conrad M,Scheid PE,Vidal O,Jeffery WR,Borowsky R,Tabin CJ

更新日期：2008-12-23 00:00:00

abstract：:A mutant strain deficient in RNase T was isolated and used to study the role of this enzyme in Escherichia coli. Strains lacking as much as 70% of RNase T activity, alone or in combination with the absence of other RNases, display normal growth properties. However, in cca strains, which lack tRNA nucleotidyltransferas...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Deutscher MP,Marlor CW,Zaniewski R

更新日期：1985-10-01 00:00:00

abstract：:Multidrug resistance in Gram-negative bacteria, to which multidrug efflux pumps such as the AcrB transporter makes a major contribution, is becoming a major public health problem. Unfortunately only a few compounds have been cocrystallized with AcrB, and thus computational approaches are essential in elucidating the i...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Vargiu AV,Nikaido H

更新日期：2012-12-11 00:00:00

abstract：:Islet transplantation offers a potential therapy to restore glucose homeostasis in type 1 diabetes patients. However, islet transplantation is not routinely successful because most islet recipients gradually lose graft function. Furthermore, serological markers of islet function are insensitive to islet loss until the...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Lu Y,Dang H,Middleton B,Zhang Z,Washburn L,Stout DB,Campbell-Thompson M,Atkinson MA,Phelps M,Gambhir SS,Tian J,Kaufman DL

更新日期：2006-07-25 00:00:00

abstract：:We have obtained the electron paramagnetic resonance spectrum of Cu2+ bound in a tetragonal single crystal of hen egg-white lysozyme. A part of this spectrum has been shown to originate from Cu2+ ions bound at the site designated as B by Teichberg et al. [Teichberg, V.I., Sharon, N., Moult, J., Smilansky, A. & Yonath,...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Hutchison CA Jr,Singel DJ,Hadad MN,Kemple MD

更新日期：1980-09-01 00:00:00

abstract：:Transcription of a right-handed double-helical DNA requires a relative rotation of the RNA polymerase and its nascent RNA around the DNA. We describe conditions under which the resistance to the rotational motion of the transcription ensemble around the DNA can be large. In such cases, the advancing polymerase generat...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Liu LF,Wang JC

更新日期：1987-10-01 00:00:00

abstract：:Four mouse POU domain genomic DNA clones--Brain-1, Brain-2, Brain-4, and Scip--and Brain-2 cDNA, which are expressed in adult brain, were cloned and the coding and noncoding regions of the genes were sequenced. The amino acid sequences of the four POU domains are highly conserved; sequences in other regions of the pro...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Hara Y,Rovescalli AC,Kim Y,Nirenberg M

更新日期：1992-04-15 00:00:00

abstract：:Cytochrome c oxidase (COX) is a 13-subunit protein complex that catalyzes the last step in mitochondrial electron transfer in mammals. Of the 10 subunits encoded by nuclear DNA (three are mtDNA products), some are expressed as tissue- and/or development-specific isoforms. For COX subunit VIII, previous work showed tha...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Goldberg A,Wildman DE,Schmidt TR,Huttemann M,Goodman M,Weiss ML,Grossman LI

更新日期：2003-05-13 00:00:00

abstract：:A rapid and convenient method has been devised to determine the binding sites for proteins on RNA. The procedure is an adaptation of one used to map DNA-protein complexes by protection against nuclease digestion. The method uses the cytotoxic ribonuclease alpha-sarcin, which hydrolyzes purines in both single- and doub...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Huber PW,Wool IG

更新日期：1984-01-01 00:00:00

abstract：:Nontypeable Hemophilus influenzae (NTHi) is an important human pathogen in both children and adults. In children, it causes otitis media, the most common childhood infection and the leading cause of conductive hearing loss in the United States. In adults, it causes lower respiratory tract infections in the setting of ...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Shuto T,Xu H,Wang B,Han J,Kai H,Gu XX,Murphy TF,Lim DJ,Li JD

更新日期：2001-07-17 00:00:00

abstract：:The complete amino acid sequence of Xenopus laevis nonmuscle myosin heavy chain B (MHC-B) has been deduced from overlapping cDNA clones isolated from an XTC cell library. RNA blots of various developmental stages, adult tissues, and XTC cells detect a single transcript of 7.5 kb which is expressed at similar levels th...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Bhatia-Dey N,Adelstein RS,Dawid IB

更新日期：1993-04-01 00:00:00

abstract：:The Kitaev model with an applied magnetic field in the [Formula: see text] direction shows two transitions: from a nonabelian gapped quantum spin liquid (QSL) to a gapless QSL at [Formula: see text] and a second transition at a higher field [Formula: see text] to a gapped partially polarized phase, where K is the stre...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Patel ND,Trivedi N

更新日期：2019-06-18 00:00:00

abstract：:Myoglobin-mediated oxygen delivery to intracellular mitochondria is demonstrated in cardiac myocytes isolated from the hearts of mature rats. Myocytes are held at high ambient oxygen pressure, 40-340 torr (5-45 kPa); sarcoplasmic myoglobin is fully oxygenated. In this condition oxygen availability does not limit respi...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Wittenberg BA,Wittenberg JB

更新日期：1987-11-01 00:00:00

abstract：:Escherichia coli O157:H7, a toxin-producing food and waterborne bacterial pathogen, has been linked to large outbreaks of gastrointestinal illness for more than two decades. E. coli O157 causes a wide range of clinical illness that varies by outbreak, although factors that contribute to variation in disease severity a...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Manning SD,Motiwala AS,Springman AC,Qi W,Lacher DW,Ouellette LM,Mladonicky JM,Somsel P,Rudrik JT,Dietrich SE,Zhang W,Swaminathan B,Alland D,Whittam TS

更新日期：2008-03-25 00:00:00

abstract：:Topological state of matter and lithium batteries are currently two hot topics in science and technology. Here we combine these two by exploring the possibility of using all-carbon-based porous topological semimetal for lithium battery anode material. Based on density-functional theory and the cluster-expansion method...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Liu J,Wang S,Sun Q

更新日期：2017-01-24 00:00:00

abstract：:In view of the extensive literature on phytochrome mutants in the Ler accession of Arabidopsis, we sought to secure a phytochrome-null line in the same genetic background for comparative studies. Here we report the isolation and phenotypic characterization of phyABCDE quintuple and phyABDE quadruple mutants in the Ler...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Hu W,Franklin KA,Sharrock RA,Jones MA,Harmer SL,Lagarias JC

更新日期：2013-01-22 00:00:00

abstract：:Osteogenin was recently purified and the amino acid sequences of tryptic peptides were determined. Osteogenin in conjunction with insoluble collagenous bone matrix induces cartilage and bone formation in vivo. To understand the mechanism of action of osteogenin, we examined its influence on periosteal cells, osteoblas...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Vukicevic S,Luyten FP,Reddi AH

更新日期：1989-11-01 00:00:00

abstract：:Soot particles produced by incomplete combustion processes are one of the major components of urban air pollution. Chemistry at their surfaces lead to the heterogeneous conversion of several key trace gases; for example NO(2) interacts with soot and is converted into HONO, which rapidly photodissociates to form OH in ...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Monge ME,D'Anna B,Mazri L,Giroir-Fendler A,Ammann M,Donaldson DJ,George C

更新日期：2010-04-13 00:00:00

abstract：:The fdhF gene encoding the 80-kDa selenopolypeptide subunit of formate dehydrogenase H from Escherichia coli contains an in-frame TGA codon at amino acid position 140, which encodes selenocysteine. We have analyzed how this UGA "sense codon" is discriminated from a UGA codon signaling polypeptide chain termination. De...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Zinoni F,Heider J,Böck A

更新日期：1990-06-01 00:00:00

abstract：:Chronic wounds represent a substantial public health problem. The development of tools that would enable sophisticated scrutiny of clinical wound tissue material is highly desirable. This work presents evidence enabling rapid specific identification and laser capture of blood vessels from human tissue in a manner whic...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Roy S,Patel D,Khanna S,Gordillo GM,Biswas S,Friedman A,Sen CK

更新日期：2007-09-04 00:00:00

abstract：:Progressive amyloid deposition in senile plaques and cortical blood vessels may play a central role in the pathogenesis of Alzheimer disease. We have used x-ray diffraction and electron microscopy to study the molecular organization and morphology of macromolecular assemblies formed by three synthetic peptides homolog...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Kirschner DA,Inouye H,Duffy LK,Sinclair A,Lind M,Selkoe DJ

更新日期：1987-10-01 00:00:00

abstract：:We report the identification and cloning of a 28-kDa polypeptide (p28) in Tetrahymena macronuclei that shares several features with the well studied heterochromatin-associated protein HP1 from Drosophila. Notably, like HP1, p28 contains both a chromodomain and a chromoshadow domain. p28 also shares features with linke...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Huang H,Wiley EA,Lending CR,Allis CD

更新日期：1998-11-10 00:00:00

abstract：:The CuAAC reaction (click chemistry) has been used in conjunction with solid-phase synthesis to produce catalytically active hairpin ribozymes around 100 nucleotides in length. Cross-strand ligation through neighboring nucleobases was successful in covalently linking presynthesized RNA strands with high efficiency (tr...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： El-Sagheer AH,Brown T

更新日期：2010-08-31 00:00:00