WWamide-1, -2 and -3: novel neuromodulatory peptides isolated from ganglia of the African giant snail, Achatina fulica.

Abstract:

:Three novel neuropeptides, isolated from ganglia of the African giant snail, Achatina fulica, were named WWamide-1, -2 and -3. These substances were biologically active heptapeptide amides with a Trp residue at both the N- and C-termini. WWamide-1, which displayed an inhibitory activity on a central neuron of the snail, exhibited peripherally modulatory effects on muscular contractions of not only the gut and other tissues of the snail but also certain tissues of other molluscs.

journal_name

FEBS Lett

journal_title

FEBS letters

authors

Minakata H,Ikeda T,Muneoka Y,Kobayashi M,Nomoto K

doi

10.1016/0014-5793(93)81458-c

subject

Has Abstract

pub_date

1993-05-24 00:00:00

pages

104-8

issue

1-2

eissn

0014-5793

issn

1873-3468

pii

0014-5793(93)81458-C

journal_volume

323

pub_type

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