Disease resistance results from foreign phytoalexin expression in a novel plant.

abstract：:Although freeze-fracture electron microscopy is normally analysed with the presumption that particles represent proteins embedded within the membrane, particles which appeared to represent inverted lipid micelles within membranes have been reported. I have now confirmed the occurrence of particles in protein-free lipo...

journal_title：Nature

authors： Miller RG

更新日期：1980-09-11 00:00:00

abstract：:How diverse cell fates and complex forms emerge and feed back to each other to sculpt functional organs remains unclear. In the developing heart, the myocardium transitions from a simple epithelium to an intricate tissue that consists of distinct layers: the outer compact and inner trabecular layers. Defects in this p...

journal_title：Nature

authors： Priya R,Allanki S,Gentile A,Mansingh S,Uribe V,Maischein HM,Stainier DYR

更新日期：2020-12-01 00:00:00

abstract：:In this Letter, the top structure of the right panel of Fig. 1a should be that of cis-9-octadecenoic acid, not trans-9-octadecenoic acid. Please see the accompanying Author Correction. This error has not been corrected online. ...

journal_title：Nature

authors： Yang Z,Wei J,Sobolev YI,Grzybowski BA

更新日期：2019-03-01 00:00:00

abstract：:The relay of information through thalamus to cortex is dynamically gated, as illustrated by the retinogeniculocortical pathway. Important to this is the inhibitory interneuron in the lateral geniculate nucleus (LGN). For the typical neuron, synaptic information arrives through postsynaptic dendrites and is transmitted...

journal_title：Nature

authors： Cox CL,Zhou Q,Sherman SM

更新日期：1998-07-30 00:00:00

abstract：:Electrochemical reduction of carbon dioxide (CO2) to carbon monoxide (CO) is the first step in the synthesis of more complex carbon-based fuels and feedstocks using renewable electricity. Unfortunately, the reaction suffers from slow kinetics owing to the low local concentration of CO2 surrounding typical CO2 reductio...

journal_title：Nature

authors： Liu M,Pang Y,Zhang B,De Luna P,Voznyy O,Xu J,Zheng X,Dinh CT,Fan F,Cao C,de Arquer FP,Safaei TS,Mepham A,Klinkova A,Kumacheva E,Filleter T,Sinton D,Kelley SO,Sargent EH

更新日期：2016-09-15 00:00:00

abstract：:Recent theory on sexual selection suggests that females in species without paternal care choose mates by their secondary sexual characters because these indicate genotypic quality which will be transmitted to the offspring. These ideas are not yet empirically supported as data quantifying the relationship between fema...

journal_title：Nature

authors： von Schantz T,Göransson G,Andersson G,Fröberg I,Grahn M,Helgée A,Wittzell H

更新日期：1989-01-12 00:00:00

abstract：:The emission of isoprene from the leaves of forest trees is a fundamental component of biosphere-atmosphere interactions, controlling many aspects of photochemistry in the lower atmosphere. As almost all commercial agriforest species emit high levels of isoprene, proliferation of agriforest plantations has significant...

journal_title：Nature

authors： Rosenstiel TN,Potosnak MJ,Griffin KL,Fall R,Monson RK

更新日期：2003-01-16 00:00:00

abstract：:Sheep learn to recognize the odours of their lambs within two hours of giving birth, and this learning involves synaptic changes within the olfactory bulb. Specifically, mitral cells become increasingly responsive to the learned odour, which stimulates release of both glutamate and GABA (gamma-aminobutyric acid) neuro...

journal_title：Nature

authors： Kendrick KM,Guevara-Guzman R,Zorrilla J,Hinton MR,Broad KD,Mimmack M,Ohkura S

更新日期：1997-08-14 00:00:00

abstract：:Tectal polarity for retinal connections remains reversible long after the anatomical pattern of neural structures has been determined. Cells in the diencephalon seem to control this polarity. Following certain embryonic operations, the diencephalon developed behind the tectum. In such cases, the polarity of the retino...

journal_title：Nature

authors： Chung SH,Cooke J

更新日期：1975-11-13 00:00:00

abstract：:Segmentation of the vertebrate hindbrain into rhombomeres is important for the anterior-posterior arrangement of cranial motor nuclei and efferent nerves. Underlying this reiterated organization, Hox genes display segmentally restricted domains of expression, such as expression of Hoxb-1 (refs 5, 6) in rhombomere 4 (r...

journal_title：Nature

authors： Studer M,Lumsden A,Ariza-McNaughton L,Bradley A,Krumlauf R

更新日期：1996-12-19 00:00:00

abstract：:Selective lowering of Abeta42 levels (the 42-residue isoform of the amyloid-beta peptide) with small-molecule gamma-secretase modulators (GSMs), such as some non-steroidal anti-inflammatory drugs, is a promising therapeutic approach for Alzheimer's disease. To identify the target of these agents we developed biotinyla...

journal_title：Nature

authors： Kukar TL,Ladd TB,Bann MA,Fraering PC,Narlawar R,Maharvi GM,Healy B,Chapman R,Welzel AT,Price RW,Moore B,Rangachari V,Cusack B,Eriksen J,Jansen-West K,Verbeeck C,Yager D,Eckman C,Ye W,Sagi S,Cottrell BA,Torpey J

更新日期：2008-06-12 00:00:00

abstract：: ...

journal_title：Nature

authors： Hershkovitz I

更新日期：2019-02-01 00:00:00

abstract：:Dengue disease is caused by four different flavivirus serotypes, which infect 390 million people yearly with 25% symptomatic cases and for which no licensed vaccine is available. Recent phase III vaccine trials showed partial protection, and in particular no protection for dengue virus serotype 2 (refs 3, 4). Structur...

journal_title：Nature

authors： Rouvinski A,Guardado-Calvo P,Barba-Spaeth G,Duquerroy S,Vaney MC,Kikuti CM,Navarro Sanchez ME,Dejnirattisai W,Wongwiwat W,Haouz A,Girard-Blanc C,Petres S,Shepard WE,Desprès P,Arenzana-Seisdedos F,Dussart P,Mongkolsapaya J

更新日期：2015-04-02 00:00:00

abstract：:Expression of Ets2, a proto-oncogene and transcription factor, occurs in a variety of cell types. During murine development it is highly expressed in newly forming cartilage, including in the skull precursor cells and vertebral primordia. Ets2 is located on human chromosome 21 (ref. 8) and is overexpressed in Down's s...

journal_title：Nature

authors： Sumarsono SH,Wilson TJ,Tymms MJ,Venter DJ,Corrick CM,Kola R,Lahoud MH,Papas TS,Seth A,Kola I

更新日期：1996-02-08 00:00:00

abstract：:Excitation-contraction coupling in skeletal muscle involves a voltage sensor in the plasma membrane which, in response to depolarization, causes an intracellular calcium-release channel to open. The skeletal isoform of the ryanodine receptor (RyR-1) functions as the Ca2+-release channel and the dihydropyridine recepto...

journal_title：Nature

authors： Nakai J,Dirksen RT,Nguyen HT,Pessah IN,Beam KG,Allen PD

更新日期：1996-03-07 00:00:00

abstract：:The terminal differentiation of myogenic cells initiates in the proximal portion of the limb bud whereas the distal region remains undifferentiated and proliferative. The apical ectodermal ridge maintains the progress zone in an undifferentiated state and induces proliferation of limb mesenchymal cells. Hox-7.1, a hom...

journal_title：Nature

authors： Song K,Wang Y,Sassoon D

更新日期：1992-12-03 00:00:00

abstract：:Fusion of myeloma cells and B lymphocytes to form hybridomas which produce monoclonal antibodies has been a major advance, but the poor efficiency and randomness of viral or polyethylene glycol fusion techniques generally gives poor yields of specific, high affinity antibodies. High voltage electrical fields with diel...

journal_title：Nature

authors： Lo MM,Tsong TY,Conrad MK,Strittmatter SM,Hester LD,Snyder SH

更新日期：1984-08-30 00:00:00

abstract：:Humans and other animals must often make decisions on the basis of imperfect evidence. Statisticians use measures such as P values to assign degrees of confidence to propositions, but little is known about how the brain computes confidence estimates about decisions. We explored this issue using behavioural analysis an...

journal_title：Nature

authors： Kepecs A,Uchida N,Zariwala HA,Mainen ZF

更新日期：2008-09-11 00:00:00

abstract：:Within the substantia nigra, the dendrites of dopaminergic neurons that project to the striatum appear to play an active and nonclassical role in the physiology of the neuron in that they release transmitter and protein, but little is known of the factors controlling release of substances from these dendrites. In this...

journal_title：Nature

authors： Nedergaard S,Bolam JP,Greenfield SA

更新日期：1988-05-12 00:00:00

abstract：:We have previously identified a structurally abnormal insulin in the serum and pancreas of a middle-aged man with diabetes mellitus which arose from a leucine for phenylalanine substitution at position 24 or 25 of the insulin B chain; further analysis of the patient's leukocyte DNA showed that one of the patient's ins...

journal_title：Nature

authors： Shoelson S,Haneda M,Blix P,Nanjo A,Sanke T,Inouye K,Steiner D,Rubenstein A,Tager H

更新日期：1983-04-07 00:00:00

abstract：:Surface gravity is a basic stellar property, but it is difficult to measure accurately, with typical uncertainties of 25 to 50 per cent if measured spectroscopically and 90 to 150 per cent if measured photometrically. Asteroseismology measures gravity with an uncertainty of about 2 per cent but is restricted to relati...

journal_title：Nature

authors： Bastien FA,Stassun KG,Basri G,Pepper J

更新日期：2013-08-22 00:00:00

abstract：:B LYMPHOCYTES are key participants in the immune response because of their specificity, their ability to take up and present antigens to T cells, and their capacity to differentiate into antibody-secreting cells. To limit reactivity to self antigens, autospecific B cells can be functionally inactivated or deleted. Dev...

journal_title：Nature

authors： Russell DM,Dembić Z,Morahan G,Miller JF,Bürki K,Nemazee D

更新日期：1991-11-28 00:00:00

abstract：:A consequence of relativity is that in the presence of an electric field, the spin and momentum states of an electron can be coupled; this is known as spin-orbit coupling. Such an interaction opens a pathway to the manipulation of electron spins within non-magnetic semiconductors, in the absence of applied magnetic fi...

journal_title：Nature

authors： Kato Y,Myers RC,Gossard AC,Awschalom DD

更新日期：2004-01-01 00:00:00

abstract：:X chromosomes evolve differently from autosomes, but general governing principles have not emerged. For example, genes with male-biased expression are under-represented on the X chromosome of D. melanogaster, but are randomly distributed in the genome of Anopheles gambiae. In direct global profiling experiments using ...

journal_title：Nature

authors： Sturgill D,Zhang Y,Parisi M,Oliver B

更新日期：2007-11-08 00:00:00

abstract：:Unmethylated CpG dinucleotides are more frequent in the genomes of bacteria and viruses than of vertebrates. We report here that bacterial DNA and synthetic oligodeoxynucleotides containing unmethylated CpG dinucleotides induce murine B cells to proliferate and secrete immunoglobulin in vitro and in vivo. This activat...

journal_title：Nature

authors： Krieg AM,Yi AK,Matson S,Waldschmidt TJ,Bishop GA,Teasdale R,Koretzky GA,Klinman DM

更新日期：1995-04-06 00:00:00

abstract：:Evolutionary relationships among the eight major lineages of Mollusca have remained unresolved despite their diversity and importance. Previous investigations of molluscan phylogeny, based primarily on nuclear ribosomal gene sequences or morphological data, have been unsuccessful at elucidating these relationships. Re...

journal_title：Nature

authors： Kocot KM,Cannon JT,Todt C,Citarella MR,Kohn AB,Meyer A,Santos SR,Schander C,Moroz LL,Lieb B,Halanych KM

更新日期：2011-09-04 00:00:00

abstract：:A cholecystokinin (CCK)-inactivating peptidase was purified and identified as a membrane-bound isoform of tripeptidyl peptidase II (EC 3.4.14.10), a cytosolic subtilisin-like peptidase of previously unknown functions. The peptidase was found in neurons responding to cholecystokinin, as well as in non-neuronal cells. B...

journal_title：Nature

authors： Rose C,Vargas F,Facchinetti P,Bourgeat P,Bambal RB,Bishop PB,Chan SM,Moore AN,Ganellin CR,Schwartz JC

更新日期：1996-04-04 00:00:00

abstract：:The tyrosine phosphatase SHP2, encoded by PTPN11, is required for the survival, proliferation and differentiation of various cell types. Germline activating mutations in PTPN11 cause Noonan syndrome, whereas somatic PTPN11 mutations cause childhood myeloproliferative disease and contribute to some solid tumours. Recen...

journal_title：Nature

authors： Yang W,Wang J,Moore DC,Liang H,Dooner M,Wu Q,Terek R,Chen Q,Ehrlich MG,Quesenberry PJ,Neel BG

更新日期：2013-07-25 00:00:00

abstract：:Since 2013 the occurrence of human infections by a novel avian H7N9 influenza virus in China has demonstrated the continuing threat posed by zoonotic pathogens. Although the first outbreak wave that was centred on eastern China was seemingly averted, human infections recurred in October 2013 (refs 3-7). It is unclear ...

journal_title：Nature

authors： Lam TT,Zhou B,Wang J,Chai Y,Shen Y,Chen X,Ma C,Hong W,Chen Y,Zhang Y,Duan L,Chen P,Jiang J,Zhang Y,Li L,Poon LL,Webby RJ,Smith DK,Leung GM,Peiris JS,Holmes EC,Guan Y,Zhu H

更新日期：2015-06-04 00:00:00

abstract：:Superantigens bind class II major histocompatibility proteins and stimulate powerful proliferative responses of T lymphocytes bearing particular V beta sequences as part of their alpha beta antigen receptor. Exogenous bacterial superantigens are responsible for food poisoning and toxic shock syndrome. Murine virus-enc...

journal_title：Nature

authors： Lafon M,Lafage M,Martinez-Arends A,Ramirez R,Vuillier F,Charron D,Lotteau V,Scott-Algara D

更新日期：1992-08-06 00:00:00