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Effect of haemodialysate and its peptide fractions on acetylcholinesterase activity in erythrocytes from healthy subjects and patients with terminal renal failure.

Abstract：

:The effects of haemodialysate and its three peptide fractions on acetylcholinesterase (AChE, E.C. 3.1.1.7) activity in erythrocytes from healthy subjects and patients with terminal renal insufficiency treated by repeated haemodialyses have been studied. It was shown that erythrocytes from haemodialysed patients display an increased activity of the enzyme if compared with those from healthy subjects. Neither haemodialysate nor any of its three peptide fractions, when incubated with erythrocytes from healthy subjects and from haemodialysed patients, have altered the activity of the enzyme, except for fraction III at the highest concentration. This fraction exerted an inhibitory effect on AChE activity of the erythrocyte derived from healthy subjects.

journal_name

Int Urol Nephrol

journal_title

International urology and nephrology

authors

Smoleński O,Tabarowski Z,Miszta H,Dabrowski Z

subject

Has Abstract

pub_date

1993-01-01 00:00:00

pages

503-8

issue

5

eissn

0301-1623

issn

1573-2584

journal_volume

25

pub_type

杂志文章

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