Abstract:
:Calorimetry was used to measure the rates of irreversible denaturation of collagen in intact mammalian lens capsules, isothermally stored in water at different temperatures, and the kinetic characteristics of the process determined. At 47.4 degrees C, the number of native collagen molecules declined by a factor of 10 in 21.4 +/- 2.9 min (this is called the D-value) and increasing the storage temperature by 2.32 +/- 0.12 degrees C reduced the D-value by a factor of 10. The activation energy of the process was 860 +/- 44 kJ mol-1, and the activation enthalpy and entropy were respectively 858 +/- 45 kJ mol-1 and 2.38 +/- 0.14 kJ mol-1 K-1. Using equations derived in the paper, these kinetic characteristics were used to predict the position and shape of the denaturation endotherms over a range of scanning rates. Comparison of the predicted and actual positions of peak maxima showed a close correspondence, demonstrating that the principal phenomenon determining the position of the peak maxima was an irreversible rate process. While there was fairly good agreement between the predicted and actual shape of the endotherm at low scanning rates, measurements at high rates were distorted by the finite response time of the calorimeter, and the agreement was poor.
journal_name
Int J Biol Macromoljournal_title
International journal of biological macromoleculesauthors
Miles CAdoi
10.1016/0141-8130(93)90025-hsubject
Has Abstractpub_date
1993-10-01 00:00:00pages
265-71issue
5eissn
0141-8130issn
1879-0003pii
0141-8130(93)90025-Hjournal_volume
15pub_type
杂志文章abstract::Interaction between split RNA aptamer and the clinically important target, HIV-1 Tat was investigated on a biosensing surface transduced by functionally choreographed multiwall carbon nanotubes (MWCNTs). Acid oxidation was performed to functionalize MWCNTs with carboxyl functional groups. X-ray photoelectron spectrosc...
journal_title:International journal of biological macromolecules
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journal_title:International journal of biological macromolecules
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journal_title:International journal of biological macromolecules
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journal_title:International journal of biological macromolecules
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journal_title:International journal of biological macromolecules
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journal_title:International journal of biological macromolecules
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journal_title:International journal of biological macromolecules
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journal_title:International journal of biological macromolecules
pub_type: 杂志文章
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journal_title:International journal of biological macromolecules
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journal_title:International journal of biological macromolecules
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journal_title:International journal of biological macromolecules
pub_type: 杂志文章
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journal_title:International journal of biological macromolecules
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journal_title:International journal of biological macromolecules
pub_type: 杂志文章
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journal_title:International journal of biological macromolecules
pub_type: 杂志文章,评审
doi:10.1016/j.ijbiomac.2016.09.056
更新日期:2016-12-01 00:00:00
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journal_title:International journal of biological macromolecules
pub_type: 杂志文章
doi:10.1016/j.ijbiomac.2018.06.173
更新日期:2018-10-15 00:00:00
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journal_title:International journal of biological macromolecules
pub_type: 杂志文章
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journal_title:International journal of biological macromolecules
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journal_title:International journal of biological macromolecules
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journal_title:International journal of biological macromolecules
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journal_title:International journal of biological macromolecules
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更新日期:2005-10-30 00:00:00
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journal_title:International journal of biological macromolecules
pub_type: 杂志文章
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journal_title:International journal of biological macromolecules
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更新日期:2016-10-01 00:00:00
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journal_title:International journal of biological macromolecules
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journal_title:International journal of biological macromolecules
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journal_title:International journal of biological macromolecules
pub_type: 杂志文章,评审
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journal_title:International journal of biological macromolecules
pub_type: 杂志文章
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更新日期:2014-08-01 00:00:00
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journal_title:International journal of biological macromolecules
pub_type: 杂志文章
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