The nature of active and passive thyroglobulin binding lymphoid cells in Obese strain (OS) chickens.

abstract：:In vitro prepared antigen-specific helper factors reactive to the synthetic polypeptide antigens poly-L(Tyr, Glu)-poly-DLAla--poly-LLys [(T, G)-A--L] or LGlu60-LAla30-LTyr10 (GAT) and bearing Ia determinants were analyzed serologically to determine the nature of the Ia determinants they expressed. I subregion-specific...

journal_title：European journal of immunology

authors： Howie S,Parish CR,David CS,McKenzie IF,Maurer PH,Feldmann M

更新日期：1979-07-01 00:00:00

abstract：:Because of their plasticity and central role in orchestrating immunity and tolerance, DCs can respond to pregnancy-specific signals, thus promoting the appropriate immune response in order to support pregnancy. Here, we show that pregnancy-specific glycoprotein (PSG1a), the major variant of PSG released into the circu...

journal_title：European journal of immunology

authors： Martínez FF,Knubel CP,Sánchez MC,Cervi L,Motrán CC

更新日期：2012-06-01 00:00:00

abstract：:Listeria monocytogenes (LM) is a foodborne Gram-positive intracellular pathogen that can cause listeriosis in humans and animals. Although phagocytes are known to be involved in the response to this infection, the role of neutrophils is not entirely clear. Here, we have demonstrated that soon after LM infection, a lar...

journal_title：European journal of immunology

authors： Wang G,Lin A,Han Q,Zhao H,Tian Z,Zhang J

更新日期：2018-09-01 00:00:00

abstract：:Secretion of proinflammatory mediators by activated macrophages plays an important role in the immune response to Trypanosoma cruzi. We have previously reported that AgC10, a glycosylphosphatidylinositol-anchored mucin from T. cruzi, inhibits TNF secretion by activated macrophages (de Diego, J., Punzon, C., Duarte, M....

journal_title：European journal of immunology

authors： Alcaide P,Fresno M

更新日期：2004-06-01 00:00:00

abstract：:Membrane-bound IgG was found only on old populations of platelets from normal individuals. This IgG could be dissociated from senescent cells by repeatedly heating the cells. Heat-eluted IgG (He-IgG) prepared from senescent red blood cells was capable of binding to either heat-treated old platelets or Vibrio cholerae ...

journal_title：European journal of immunology

authors： Khansari N,Fudenberg HH

更新日期：1983-12-01 00:00:00

abstract：:The glycolipid alpha-galactosylceramide (alpha-GalCer) is a potent activator of invariant natural killer T (iNKT) cells and has been shown to be an effective agent against cancer, infections and autoimmune diseases. The effectiveness of alpha-GalCer and its alkyl chain analogues depends on efficient loading and presen...

journal_title：European journal of immunology

authors： Denkberg G,Stronge VS,Zahavi E,Pittoni P,Oren R,Shepherd D,Salio M,McCarthy C,Illarionov PA,van der Merwe A,Besra GS,Dellabona P,Casorati G,Cerundolo V,Reiter Y

更新日期：2008-03-01 00:00:00

abstract：:In this investigation we compare the repopulation of the CD8+ T cell compartments of bone marrow (BM) chimeras by either normal nontransgenic or T cell receptor (TcR) alpha beta-transgenic (TG) CD8+ T cells, the fate of TG and non-TG CD8+ T cells in different parabionts and the survival of TG and non-TG peripheral CD8...

journal_title：European journal of immunology

authors： Freitas AA,Agenes F,Coutinho GC

更新日期：1996-11-01 00:00:00

abstract：:Persistent polyclonal B cell lymphocytosis (PPBL) is a hematological disorder diagnosed predominantly in women, characterized by a polyclonal increase in the number of peripheral blood B lymphocytes. Abnormality of the B cell population was evidenced by the finding of multiple bcl-2/Ig gene rearrangements and an addit...

journal_title：European journal of immunology

authors： Loembé MM,Néron S,Delage R,Darveau A

更新日期：2002-12-01 00:00:00

abstract：:Type I IFN are cytokines which play a central role in host resistance to viral or microbial infections and are important components linking innate and adaptive immunity. We and others have previously demonstrated that the production of IFN-beta by DC following bacterial infections or TLR triggering influences, in an a...

journal_title：European journal of immunology

authors： Remoli ME,Gafa V,Giacomini E,Severa M,Lande R,Coccia EM

更新日期：2007-12-01 00:00:00

abstract：:The contribution of Gal alpha 1,3Gal (alpha-Gal) to cell-mediated organ xenograft rejection is controversial. We have used recombinant lentiviruses encoding a porcine alpha 1,3 galactosyltransferase (alpha 1,3GalT) to obtain alpha-Gal-expressing primary human aortic endothelial cells (HAEC) at a frequency of 70-90%. T...

journal_title：European journal of immunology

authors： He Z,Ehrnfelt C,Kumagai-Braesch M,Islam KB,Holgersson J

更新日期：2004-04-01 00:00:00

abstract：:In humans and in BALB/c mice, immune responses to the hormone insulin use evolutionarily related VHV (human) and VHIX (murine) gene families. To determine if these structural relationships include regulatory elements, BALB/c mice were pretreated with autologous immunoglobulin G (IgG) monoclonal antibodies (mAb) that r...

journal_title：European journal of immunology

authors： Thomas JW

更新日期：1992-09-01 00:00:00

abstract：:The modulatory activity of dextran sulfate with a relative molecular mass of 8 and 500 kDa and pentosan polysulfate with a relative molecular mass of 6 kDa on human T cell surface molecules CD2, CD3, CD4, CD8 and HLA-DR was investigated by analytical flow cytometry. The 500-kDa dextran sulfate induces a complete disap...

journal_title：European journal of immunology

authors： Thiele B,Braig HR,Ehm I,Kunze R,Ruf B

更新日期：1989-06-01 00:00:00

abstract：:Murine cytolytic T cell lines have been analyzed for the expression of two surface glycoproteins called T145 and T130. T145, known to be expressed by activated cytolytic T cells, is also expressed by such lines, but T130, which has been described by a universal T cell marker, is not. Our results suggest a structural r...

journal_title：European journal of immunology

authors： Conzelmann A,Pink R,Acuto O,Mach JP,Dolivo S,Nabholz M

更新日期：1980-11-01 00:00:00

abstract：:Abnormal cytokine production can contribute in many instances to the development of pathology. Our study focuses on the regulation of interleukin (IL)-6 production in vitro in brain-specific endothelial cells (BEC) under physiological conditions and in a model of human T leukemia virus-1 (HTLV-1) infection. IL-6 produ...

journal_title：European journal of immunology

authors： Rott O,Tontsch U,Fleischer B,Cash E

更新日期：1993-08-01 00:00:00

abstract：:The activation requirements for antigen-dependent proliferation of CD4+ T cells are well documented, while the events leading to the inactivation phase are poorly understood. Here, we tested the hypothesis that the lymphocyte-activation gene 3 (LAG-3), a second major histocompatibility complex (MHC) class II ligand, p...

journal_title：European journal of immunology

authors： Huard B,Tournier M,Hercend T,Triebel F,Faure F

更新日期：1994-12-01 00:00:00

abstract：:Once generated during an infection, memory CD8+ T cells can provide long-lasting protection against reinfection with an intracellular pathogen, but the longevity of this defense depends on the ability of these pathogen-specific memory cells to be maintained. It is generally believed that the bone marrow plays an impor...

journal_title：European journal of immunology

authors： Nolte MA,Goedhart M,Geginat J

更新日期：2017-11-01 00:00:00

abstract：:Injection of M-1 (Cmu), G-1 (Cgamma) heterozygous chickens on the day of hatch with anti-IgM-1 antiserum induced allotype suppression from which chickens recovered over a period of approximately 4 months. The suppression of the serum IgM-1 levels was matched by a decrease in the number of splenic and peripheral blood ...

journal_title：European journal of immunology

authors： Ratcliffe MJ,Ivanyi J

更新日期：1981-04-01 00:00:00

abstract：:The magnitude of the IgE antibody response against the phosphorylcholine (PC) hapten and the rate of age-related change of IgE formation is polymorphic in the three long-lived and six relatively short-lived strains of mice studied. Long-lived mice showed an early increase, followed by a decline in the levels of anti-P...

journal_title：European journal of immunology

authors： Gerber V,Ponnappan U,Heusser CH,Blaser K,Cinader B

更新日期：1986-06-01 00:00:00

abstract：:We have followed the fate of mature CD8+ T cells with a male-specific transgenic T cell receptor after antigenic stimulation with hemopoietic cells in the absence or presence of help. Our data show that mature CD8+ T cells can be deleted after a 3-week period of transient activation and that help, e.g. in the form of ...

journal_title：European journal of immunology

authors： Kirberg J,Bruno L,von Boehmer H

更新日期：1993-08-01 00:00:00

abstract：:Chemokine receptors are important for recruiting leukocytes to sites of infection and may contribute to immune cell activation. The present study investigated the role of the chemokine receptor CCR2 in polymicrobial septic peritonitis. The results showed that peritoneal production of the CCR2 ligands CCL2 and CCL12 in...

journal_title：European journal of immunology

authors： Feterowski C,Mack M,Weighardt H,Bartsch B,Kaiser-Moore S,Holzmann B

更新日期：2004-12-01 00:00:00

abstract：:In this study two newly developed monoclonal antibodies, ED5 and ED6, are described, which specifically recognize nonlymphoid cells in B cell follicles of spleen and lymph nodes. Enzyme and immunocytochemical techniques demonstrated that ED5 and ED6 stain two different types of reticulum cells. The staining patterns w...

journal_title：European journal of immunology

authors： Jeurissen SH,Dijkstra CD

更新日期：1986-05-01 00:00:00

abstract：:The role of complement receptors on the localization of T and B cells in the spleen of mice was studied using short-term homing experiments in cobra venom factor (CoF)-treated animals. The localization ratio of B and T cells in the spleen of CoF-treated mice decreased significantly compared to control recipients. No c...

journal_title：European journal of immunology

authors： Kraal G,Van Hoogstraten I,Klerx JP,Van Dijk H

更新日期：1985-07-01 00:00:00

abstract：:Cytomegalovirus latently infects myeloid cells; however, the acute effects of the virus on this cell subset are poorly characterised. We demonstrate that systemic cytomegalovirus infection induced rapid activation of monocytes in the bone marrow, characterised by upregulation of CD69, CD11c, Ly6C and M-CSF receptor. A...

journal_title：European journal of immunology

authors： Wikstrom ME,Khong A,Fleming P,Kuns R,Hertzog PJ,Frazer IH,Andoniou CE,Hill GR,Degli-Esposti MA

更新日期：2014-02-01 00:00:00

abstract：:The role of T cell differentiation antigens in antigen-specific and nonspecific cytotoxicity by human cytotoxic T lymphocyte (CTL) clones was investigated. In contrast to other reports, several monoclonal antibodies (mAb) against the T3 antigen only marginally blocked antigen-specific cytotoxicity at high concentratio...

journal_title：European journal of immunology

authors： Schrezenmeier H,Kurrle R,Wagner H,Fleischer B

更新日期：1985-10-01 00:00:00

abstract：:Stromal elements are major components of lymphoid tissues contributing to both tissue architecture and function. In this study we report on the phenotype and function of fibroblast-like stromal cells obtained from human spleen. These cells express high levels of CD44 and ICAM-1 and moderate levels of VLA-4, VCAM, CD40...

journal_title：European journal of immunology

authors： Skibinski G,Skibinska A,Stewart GD,James K

更新日期：1998-12-01 00:00:00

abstract：:CD23, the low-affinity IgE receptor, is up-regulated on interleukin (IL)-4-stimulated B cells and monocytes, with a concomitant increase in the release of soluble fragments of CD23 (sCD23) into the medium by proteolytic processing of the surface-bound intact CD23. The effect of inhibition of the processing of CD23 on ...

journal_title：European journal of immunology

authors： Christie G,Barton A,Bolognese B,Buckle DR,Cook RM,Hansbury MJ,Harper GP,Marshall LA,McCord ME,Moulder K,Murdock PR,Seal SM,Spackman VM,Weston BJ,Mayer RJ

更新日期：1997-12-01 00:00:00

abstract：:Murine Thy-1+, TcR V gamma 3/V delta 1+ dendritic epidermal T cells (DETC) differ from most other T cell subsets by the absence of CD4 and CD8 antigens as well as the lack of CD5 expression. To see whether negativity for those antigens is an intrinsic feature of a given T cell population or if such triple-negative T c...

journal_title：European journal of immunology

authors： Payer E,Kutil R,Stingl G

更新日期：1994-06-01 00:00:00

abstract：:Human ILCs are classically categorized into five subsets; cytotoxic CD127- CD94+ NK cells and non-cytotoxic CD127+ CD94- , ILC1s, ILC2s, ILC3s, and LTi cells. Here, we identify a previously unrecognized subset within the CD127+ ILC population, characterized by the expression of the cytotoxic marker CD94. These CD94+ I...

journal_title：European journal of immunology

authors： Krabbendam L,Heesters BA,Kradolfer CMA,Spits H,Bernink JH

更新日期：2020-12-09 00:00:00

abstract：:To study the question when and where self peptides become associated with major histocompatibility complex class II molecules for tolerance induction, we recently developed a system in which the intracellular site(s) of antigen expression could be manipulated using gene cloning techniques. We previously constructed a ...

journal_title：European journal of immunology

authors： Bikoff EK

更新日期：1991-06-01 00:00:00

abstract：:Human Vγ9Vδ2 T cells are potent anti-tumor lymphocytes that specifically respond to pyrophosphate (phospho-) antigens, which constitute the basis of current γδ T-cell-based immunotherapy strategies. Despite a clear involvement of the TCR, the costimulation requirements of Vγ9Vδ2 T cells remain ill-defined. Here, we sh...

journal_title：European journal of immunology

authors： DeBarros A,Chaves-Ferreira M,d'Orey F,Ribot JC,Silva-Santos B

更新日期：2011-01-01 00:00:00