The effect of interleukin 1 alpha on acetaminophen-induced hepatotoxicity.

abstract：BACKGROUND:IL-10 family cytokines are associated with the host immune response to pulmonary tuberculosis (PTB), but their association with host response in tuberculous lymphadenitis (TBL) is not known. METHODS:Hence, we examined the circulating levels of the whole panel of IL-10 family cytokines in TBL (n = 44) and co...

journal_title：Cytokine

authors： Kathamuthu GR,Kumar NP,Moideen K,Baskaran D,Hissar S,Shrinivasa BM,Sridhar R,Babu S

更新日期：2018-11-01 00:00:00

abstract：:Inflammatory processes are implicated in gastric cancer development. In contrast, the role of inflammation and proinflammatory cytokines in established cancer remains to be clarified. We investigated the contribution of IL-17A versus IL-17F-mediated intracellular signalling pathways in human gastric adenocarcinoma AGS...

journal_title：Cytokine

authors： Zhou Y,Toh ML,Zrioual S,Miossec P

更新日期：2007-06-01 00:00:00

abstract：:Inflammatory bowel diseases are characterized by dysregulated immune response to the normal microflora and structural and functional changes of the enteric nervous system which occur in inflamed as well as non-inflamed areas of the bowel. This study describes the changes in the expression of nerve growth factor (NGF) ...

journal_title：Cytokine

authors： Barada KA,Mourad FH,Sawah SI,Khoury C,Safieh-Garabedian B,Nassar CF,Tawil A,Jurjus A,Saadé NE

更新日期：2007-03-01 00:00:00

abstract：:CC Chemokine ligand 22 (Ccl22) is a selective, high affinity ligand at the CC chemokine receptor 4 (Ccr4). We have identified cDNAs encoding both ligand and receptor of the Ccl22-Ccr4 pair in cDNA libraries of the anterior hypothalamus/pre-optic area (AH/POA) by PCR. The AH/POA is the key brain region where endogenous...

journal_title：Cytokine

authors： Osborn O,Sanchez-Alavez M,Dubins JS,Gonzalez AS,Morrison B,Hadcock JR,Bartfai T

更新日期：2011-03-01 00:00:00

abstract：:Interleukin (IL)-7 is a potent proliferation, activation, and survival cytokine for CD8+ T cells to improve viral and tumor specific CD8+ T cell responses. However, the role of IL-7 in regulation of dysfunctional hepatitis C virus (HCV)-specific CD8+ T cells was not fully elucidated. Thus, a total of 53 patients with ...

journal_title：Cytokine

authors： Hou H,Kang Y,Zeng Y,Li Y,Shang J

更新日期：2018-02-01 00:00:00

abstract：:Several studies assessed the associations of interleukin-10 (IL-10) polymorphisms with asthma in different populations. However, the results were inconclusive. The aim of the present study was to further assess the associations by the method of meta-analysis. Pubmed, EMBASE, Wanfang Database, China National Knowledge ...

journal_title：Cytokine

authors： Nie W,Fang Z,Li B,Xiu QY

更新日期：2012-12-01 00:00:00

abstract：:Pro-inflammatory cytokines are important mediators in tissue responses to a wide range of endogenous (e.g. autoantigens) and exogenous (e.g. infections, wounds, biomaterials) stimuli. The complex interactions taking place between different cell types in such processes are difficult to examine in vivo. Here we studied ...

journal_title：Cytokine

authors： Gretzer C,Thomsen P,Jansson S,Nilsson M

更新日期：2000-01-01 00:00:00

abstract：:Inhibition of inflammation is one of the possible therapeutic approaches for Insulin resistance (IR) during type 2 diabetes mellitus (T2DM). In the current study we investigated the effects of palmitate and chicoric acid (CA) on inflammation in peripheral blood mononuclear cells (PBMCs) of newly diagnosed T2DM patient...

journal_title：Cytokine

authors： Sadeghabadi ZA,Ziamajidi N,Abbasalipourkabir R,Mohseni R,Borzouei S

更新日期：2019-04-01 00:00:00

abstract：:Interleukin 2 (IL-2) and interleukin 12 (IL-12) have potent anti-tumour activity as single agent therapy against several different murine and human tumours. Combining these cytokines may result in improved therapeutic effectiveness, however, the toxicity associated with simultaneous administration is prohibitive. This...

journal_title：Cytokine

authors： Kaufman HL,Swartout BG,Hörig H,Lubensky I

更新日期：2002-01-07 00:00:00

abstract：:C-reactive protein (CRP) has been demonstrated to induce blood-brain barrier disruption (BBB) involving NAD(P)H-oxidase dependent oxidative stress. It is unclear why CRP affects the BBB and not other vascular beds following stroke. Therefore we examined CRP receptor and NAD(P)H-oxidase expression levels in bovine brai...

journal_title：Cytokine

authors： Closhen D,Bender B,Luhmann HJ,Kuhlmann CR

更新日期：2010-05-01 00:00:00

abstract：:Although G-CSF mobilized peripheral blood stem cell (PBSC) transplantation is commonly used in adults, bone marrow (BM) is still the preferred stem cell source in pediatric stem cell transplantation. Despite the fact that G-CSF is increasingly being used to enhance the hematopoietic stem/progenitor cell (HSPC) yield i...

journal_title：Cytokine

authors： Aerts-Kaya F,Kilic E,Köse S,Aydin G,Cagnan I,Kuskonmaz B,Uckan-Cetinkaya D

更新日期：2020-12-28 00:00:00

abstract：:Three representative cytokines interleukin (IL-8), RANTES and tumour necrosis factor alpha (TNF-alpha) have a concentration-dependent chemotactic effect on the unicellular Tetrahymena. Maximal effective concentrations of IL-8 (1 ng/ml) and RANTES (75 ng/ml) are in the same range as in mammals, which indicates an evolu...

journal_title：Cytokine

authors： Köhidai L,Csaba G

更新日期：1998-07-01 00:00:00

abstract：:Rheumatoid arthritis (RA) is an immune disease in which the pathological immune reaction is thought to be initiated by the presentation of an (auto) antigen or superantigen by MHC class II positive cells to CD4 T cells. These successive immunological events can be studied by the cytokines produced at the different sta...

journal_title：Cytokine

authors： Zangerle PF,De Groote D,Lopez M,Meuleman RJ,Vrindts Y,Fauchet F,Dehart I,Jadoul M,Radoux D,Franchimont P

更新日期：1992-11-01 00:00:00

abstract：:Lung cancer is a common malignant disease, nearly 2.09 million new patients occurred last year. Approximately 85% of the patients are classified as non-small-cell lung cancer (NSCLC). It is therefore important to identify new diagnostic and prognostic biomarkers for the early detection of this disease. The presented s...

journal_title：Cytokine

authors： Cai D,Xu Y,Ding R,Qiu K,Zhang R,Wang H,Huang L,Xie X,Yan H,Deng Y,Lin X,Shao J,Luo X,Duan C

更新日期：2020-02-01 00:00:00

abstract：OBJECTIVE:The effects of LDL-apheresis (LDLa) with dextran sulphate on plasma cytokines in 6 homozygous familial hypercholesterolemic (HozFH) patients, were evaluated. METHODS:Plasma IL-1α; IL-1ra; IL-4; IL-6; IL-10; IL-12(p40); IL-12(p70); TNF-α, sTNF-R, VEGF, VEGF-R1, E-Selectin (ESEL), and P-Selectin (PSEL) concent...

journal_title：Cytokine

authors： Stefanutti C,Vivenzio A,Di Giacomo S,Ferraro PM

更新日期：2011-08-01 00:00:00

abstract：:Interleukin-8 (IL-8/CXCL8) is widely expressed in fetal tissues although inflammatory changes are not seen. Circulating IL-8 is comprised of an endothelial-derived [ala-IL-8](77) isoform and another, more potent [ser-IL-8](72) secreted by most other cells; [ala-IL-8](77) can be converted into [ser-IL-8](72) by proteol...

journal_title：Cytokine

authors： Maheshwari A,Voitenok NN,Akalovich S,Shaik SS,Randolph DA,Sims B,Patel RP,Killingsworth CR,Fallon MB,Ohls RK

更新日期：2009-04-01 00:00:00

abstract：AIM:How irreversible electroporation (IRE) affect immune status is still kept unknown. This preclinical study is to investigate its local and systemic immune reaction both on tumor-bearing and tumor free animals. METHODS:Liver ablation was performed by a standard IRE instrument and proposal. Altogether 57 tumor bearin...

journal_title：Cytokine

authors： Chen X,Ren Z,Yin S,Xu Y,Guo D,Xie H,Zhou L,Wu L,Jiang J,Li H,Sun J,Zheng S

更新日期：2017-05-01 00:00:00

abstract：:Literature studies suggest important protective effects of low-frequency, low-energy pulsed electromagnetic fields (PEMFs) on inflammatory pathways affecting joint and cerebral diseases. However, it is not clear on which bases they affect neuroprotection and the mechanism responsible is yet unknown. Therefore the aim ...

journal_title：Cytokine

authors： Merighi S,Gessi S,Bencivenni S,Battistello E,Vincenzi F,Setti S,Cadossi M,Borea PA,Cadossi R,Varani K

更新日期：2020-01-01 00:00:00

abstract：:Interleukin 6 (IL-6) stimulates fibrinogen (Fg) gene expression both in vivo and in vitro; while interleukin 1 (IL-1) paradoxically stimulates in vivo, yet inhibits in vitro, Fg synthesis. The naturally occurring interleukin 1 receptor antagonist (IL-1ra) and passive immunization with anti-IL-6 antiserum were used to ...

journal_title：Cytokine

authors： Rokita H,Neta R,Sipe JD

更新日期：1993-09-01 00:00:00

abstract：:Tumour necrosis factor alpha(TNF-alpha) is one of the most important pro-inflammatory cytokines, which plays an important role in host defense and acute inflammation related to tissue injury. The major source of TNF-alpha has been shown to be immune cells such as macrophages and neutrophils. In the present study, we d...

journal_title：Cytokine

authors： McRitchie DI,Isowa N,Edelson JD,Xavier AM,Cai L,Man HY,Wang YT,Keshavjee SH,Slutsky AS,Liu M

更新日期：2000-06-01 00:00:00

abstract：:In atherosclerotic plaques, macrophages (MAC) and smooth muscle cells (SMC) frequently reside in close proximity and resistin (Rs) and fractalkine (Fk) are present at increased levels, resistin being associated with CD68 macrophages and fractalkine predominantly associated with intimal SMC; however, their role in this...

journal_title：Cytokine

authors： Tucureanu MM,Butoi E,Gan AM,Stan D,Constantinescu CA,Calin M,Simionescu M,Manduteanu I

更新日期：2016-07-01 00:00:00

abstract：:Bullous pemphigoid (BP) is an autoimmune blistering skin disease characterized by the presence of autoantibodies to normal components of the hemidesmosome (BPAg1 and BPAg2). Histology of skin lesions demonstrate a subepidermal vesicle and a predominantly eosinophilic dermal cellular infiltrate. Interleukin 5 (IL-5) pl...

journal_title：Cytokine

authors： Engineer L,Bhol K,Kumari S,Razzaque Ahmed A

更新日期：2001-01-07 00:00:00

abstract：:Interferon-gamma (IFN-gamma) is a potent immunomodulatory cytokine whose physiological roles are modulated by the extracellular matrix. Here, circular dichroism and fluorescence spectroscopic techniques are used to demonstrate that low molecular weight heparin and chondroitin sulfate cause significant changes in secon...

journal_title：Cytokine

authors： Balasubramanian V,Ramanathan M

更新日期：2000-05-01 00:00:00

abstract：:Ocular trauma affects 20% of Americans in their lifetime and can cause permanent visual system damage. We have used a mouse model of ocular trauma (exposure to an air blast from a paintball gun) to examine pathways that trigger the resulting retinal damage and to develop treatment strategies that might ameliorate the ...

journal_title：Cytokine

authors： Jiang Y,Pagadala J,Miller DD,Steinle JJ

更新日期：2014-12-01 00:00:00

abstract：:This article has been retracted: please see Elsevier Policy on Article Withdrawal (https://www.elsevier.com/about/our-business/policies/article-withdrawal). This article has been retracted at the request of the Editor-in-Chief. Image duplication has been observed within Figure 1g-h. The corresponding author has been a...

journal_title：Cytokine

authors： Galloway C,Chattopadhyay M

更新日期：2013-07-01 00:00:00

abstract：BACKGROUND:Endothelial injury is recognized to trigger organ failures during the first 48h of septic shock. We evaluate endothelial biomarkers at ICU admission in their ability to predict severity, outcome, and organ failures in septic shock patients. METHODS:This prospective observational pilot study was conducted in...

journal_title：Cytokine

authors： Palud A,Parmentier-Decrucq E,Pastre J,De Freitas Caires N,Lassalle P,Mathieu D

更新日期：2015-06-01 00:00:00

abstract：:The aim of this research was to assess the relationship between plasma adiponectin, leptin, resistin, tumor necrosis factor alpha (TNF-α) levels and echocardiographic parameters of ventricular remodeling in patients with coronary artery disease, without acute myocardial infarction. The study population consisted of 49...

journal_title：Cytokine

authors： Farcaş AD,Rusu A,Stoia MA,Vida-Simiti LA

更新日期：2018-03-01 00:00:00

abstract：:Muscle wasting is a decline in skeletal muscle mass and function that is associated with aging, obesity, and a spectrum of pathologies including cancer. Cancer-associated wasting not only reduces quality of life, but also directly impacts cancer mortality, chemotherapeutic efficacy, and surgical outcomes. There is an ...

journal_title：Cytokine

authors： Hogan KA,Cho DS,Arneson PC,Samani A,Palines P,Yang Y,Doles JD

更新日期：2018-07-01 00:00:00

abstract：:Previously, two binding sites for interleukin 5 (IL-5) were identified on the IL-5 receptor alpha chain (IL-5Ralpha). They are located within the CD loop of the first fibronectin type III (FnIII)-like domain and the EF loop of the second FnIII-like domain. The first binding site was identified by exploiting the differ...

journal_title：Cytokine

authors： Czabotar PE,Holland J,Sanderson CJ

更新日期：2000-07-01 00:00:00

abstract：:The self-renewal capacity of germline derived stem cells (GSCs) makes them an ideal source for research and use in clinics. Despite the presence of active gene network similarities between embryonic stem cells (ESCs) and GSCs, there are unanswered questions regarding the roles of evolutionary conserved genes in GSCs. ...

journal_title：Cytokine

authors： Farshchian M,Matin MM,Armant O,Geerts D,Dastpak M,Nakhaei-Rad S,Tajeran M,Jebelli A,Shahriyari M,Bahrami M,Fallah A,Yaghoobi V,Mirahmadi M,Abbaszadegan MR,Bahrami AR

更新日期：2018-06-01 00:00:00