Similarities among hypervariable segments of immunoglobulin chains.

Abstract:

:A human lambdaV (Mcg) and a human lambdaII (Vil) myeloma protein have identical sequences in their first hypervariable segments although they differ at 21 positions throughout the variable region. If a different structural gene is responsible for each subgroup, the findings favor insertion of information for the hypervariable or complementarity-determining segments.

authors

Wu TT,Kabat EA,Bilofsky H

doi

10.1073/pnas.72.12.5107

subject

Has Abstract

pub_date

1975-12-01 00:00:00

pages

5107-10

issue

12

eissn

0027-8424

issn

1091-6490

journal_volume

72

pub_type

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