Chloroquine excretion in semen following antimalarial-drug administration.

Abstract:

:The study described here was carried out to establish whether or not chloroquine was excreted in semen. Chloroquine was assayed in the semen of eight male volunteers (aged between 19 and 45 years) by a fluorimetric method before and after taking a total dose of 1.500 mg chloroquine base corresponding to the accepted dosage of the drug in malarial chemotherapy. Mean pre- and post-drug administration levels of 0.7 +/- 0.2 microM and 5.7 +/- 0.6 microM were obtained respectively, indicating a significant excretion of chloroquine in semen.

journal_name

Andrologia

journal_title

Andrologia

authors

Adeeko AO,Dada OA

doi

10.1111/j.1439-0272.1994.tb00782.x

subject

Has Abstract

pub_date

1994-05-01 00:00:00

pages

165-6

issue

3

eissn

0303-4569

issn

1439-0272

journal_volume

26

pub_type

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