Abstract:
:Gastric juice ascorbic acid concentrations were examined in black and white patients. Significantly lower concentrations were found in blacks, in the absence of a significant difference in the plasma concentration of vitamin C between races. Blacks had higher prevalence of Helicobacter pylori infection, higher gastric pH, more severe acute and chronic inflammation of the gastric mucosa and higher frequency of Lewis (a-b-) phenotype. Although most of these factors have been related to low ascorbic acid levels in gastric juice, none of them could account entirely for the difference between races either individually or after joint consideration. These observations may help to explain the high incidence of gastric carcinoma among the black population in southern Louisiana.
journal_name
Cancer Lettjournal_title
Cancer lettersauthors
Ruiz B,Correa P,Fontham ET,Rood JC,Malcom GT,Torrado J,Perez A,Ramakrishnan T,Hunter FMdoi
10.1016/0304-3835(94)90336-0subject
Has Abstractpub_date
1994-08-15 00:00:00pages
323-9issue
1-2eissn
0304-3835issn
1872-7980pii
0304-3835(94)90336-0journal_volume
83pub_type
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