Abstract：
:The rooting of intraspecific gene or haplotype trees has proven to be difficult using the traditional techniques of rooting species trees such as outgroups. As an alternative, we apply neutral coalescent theory to the problems of determining the root of an intraspecific gene tree and the relative ages of the haplotypes. By using a recursive equation, exact root probabilities can be calculated for small cladograms and sample sizes. These exact probabilities indicate that root probabilities are not very sensitive to the parameter theta, which is four times the mutation rate times the inbreeding effective size. The exact probabilities also indicate that root probabilities are not very sensitive to the absolute numbers of each haplotype (allele) class, only their relative proportions. The exact method, unfortunately, is not feasible for implementation with larger data sets with present algorithms and computers. However, the exact results suggested a simple heuristic for determining outgroup weights; that is, finding the haplotype that is the oldest in the sample and that can serve as an outgroup for the remainder of the haplotype tree. Computer simulations revealed that these outgroup weights are strongly correlated with actual age and are much better indicators of haplotype age than is the haplotype frequency, another commonly used indicator of relative age.
journal_name
Mol Phylogenet Evoljournal_title
Molecular phylogenetics and evolutionauthors
Castelloe J,Templeton ARdoi
10.1006/mpev.1994.1013subject
Has Abstractpub_date
1994-06-01 00:00:00pages
102-13issue
2eissn
1055-7903issn
1095-9513pii
S1055-7903(84)71013-Xjournal_volume
3pub_type
杂志文章abstract：:The superfamily Conoidea is one of the most speciose groups of marine mollusks, with estimates of about 340 recent valid genera and subgenera, and 4000 named living species. Previous classifications were based on shell and anatomical characters, and clades and phylogenetic relationships are far from well assessed. Bas...
journal_title：Molecular phylogenetics and evolution
pub_type： 杂志文章
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journal_title：Molecular phylogenetics and evolution
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journal_title：Molecular phylogenetics and evolution
pub_type： 杂志文章
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journal_title：Molecular phylogenetics and evolution
pub_type： 杂志文章
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journal_title：Molecular phylogenetics and evolution
pub_type： 杂志文章
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journal_title：Molecular phylogenetics and evolution
pub_type： 杂志文章
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journal_title：Molecular phylogenetics and evolution
pub_type： 杂志文章
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更新日期：2011-03-01 00:00:00
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journal_title：Molecular phylogenetics and evolution
pub_type： 杂志文章
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更新日期：2019-12-01 00:00:00
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journal_title：Molecular phylogenetics and evolution
pub_type： 杂志文章
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更新日期：2016-01-01 00:00:00
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journal_title：Molecular phylogenetics and evolution
pub_type： 杂志文章
doi：10.1006/mpev.1995.1021
更新日期：1995-09-01 00:00:00
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journal_title：Molecular phylogenetics and evolution
pub_type： 杂志文章
doi：10.1016/j.ympev.2009.09.025
更新日期：2010-02-01 00:00:00
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journal_title：Molecular phylogenetics and evolution
pub_type： 杂志文章
doi：10.1016/j.ympev.2004.11.004
更新日期：2005-04-01 00:00:00
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journal_title：Molecular phylogenetics and evolution
pub_type： 杂志文章
doi：10.1016/j.ympev.2008.03.026
更新日期：2008-06-01 00:00:00
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journal_title：Molecular phylogenetics and evolution
pub_type： 杂志文章
doi：10.1016/j.ympev.2015.10.001
更新日期：2016-02-01 00:00:00
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journal_title：Molecular phylogenetics and evolution
pub_type： 杂志文章
doi：10.1016/j.ympev.2012.06.014
更新日期：2012-10-01 00:00:00
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journal_title：Molecular phylogenetics and evolution
pub_type： 杂志文章
doi：10.1016/j.ympev.2008.03.018
更新日期：2008-07-01 00:00:00
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journal_title：Molecular phylogenetics and evolution
pub_type： 杂志文章
doi：10.1016/j.ympev.2009.07.025
更新日期：2009-12-01 00:00:00
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journal_title：Molecular phylogenetics and evolution
pub_type： 杂志文章
doi：10.1006/mpev.1998.0526
更新日期：1998-10-01 00:00:00
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journal_title：Molecular phylogenetics and evolution
pub_type： 杂志文章
doi：10.1016/j.ympev.2006.09.020
更新日期：2007-03-01 00:00:00
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journal_title：Molecular phylogenetics and evolution
pub_type： 杂志文章
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更新日期：2010-12-01 00:00:00
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journal_title：Molecular phylogenetics and evolution
pub_type： 杂志文章
doi：10.1006/mpev.1999.0677
更新日期：1999-12-01 00:00:00
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journal_title：Molecular phylogenetics and evolution
pub_type： 杂志文章
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更新日期：2016-12-01 00:00:00
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journal_title：Molecular phylogenetics and evolution
pub_type： 杂志文章
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更新日期：2021-03-01 00:00:00
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journal_title：Molecular phylogenetics and evolution
pub_type： 杂志文章
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更新日期：2016-01-01 00:00:00
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journal_title：Molecular phylogenetics and evolution
pub_type： 杂志文章
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更新日期：2014-07-01 00:00:00
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journal_title：Molecular phylogenetics and evolution
pub_type： 杂志文章
doi：10.1016/j.ympev.2017.10.018
更新日期：2018-02-01 00:00:00
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journal_title：Molecular phylogenetics and evolution
pub_type： 杂志文章
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更新日期：2014-12-01 00:00:00
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journal_title：Molecular phylogenetics and evolution
pub_type： 杂志文章
doi：10.1006/mpev.2001.0934
更新日期：2001-05-01 00:00:00
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journal_title：Molecular phylogenetics and evolution
pub_type： 杂志文章
doi：10.1006/mpev.2000.0864
更新日期：2001-01-01 00:00:00
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journal_title：Molecular phylogenetics and evolution
pub_type： 杂志文章
doi：10.1016/j.ympev.2013.03.014
更新日期：2013-07-01 00:00:00
