Abstract:
:Sulfated glycoprotein 2 (SGP-2) mRNA progressively increased in the ventral prostate of the aging rat, reaching, at 24 months, 4-fold higher than at 3 months. Ornithine decarboxylase (ODC) mRNA peaked at 6 months (4-fold increase), and at 12 and 24 months was maintained at higher levels than at 3 months. ODC enzymatic activity was enhanced at 6 months to a much smaller extent than its own mRNA, the values at 12 and 24 months dropping to below those at 3 months. Putrescine (Put), spermidine (Spd) and spermine (Sp) concentrations also peaked at 6 months (100% increase for Put, 50% for Sp and Spd). At 24 months, Put and Spd were diminished, and Sp was unchanged with respect to the 3-month values. Under the same conditions, glyceraldehyde-3-phosphate dehydrogenase mRNA did not undergo significant alterations.
journal_name
FEBS Lettjournal_title
FEBS lettersauthors
Bettuzzi S,Strocchi P,Marinelli M,Astancolle S,Davalli P,Corti Adoi
10.1016/0014-5793(94)00609-1subject
Has Abstractpub_date
1994-07-18 00:00:00pages
255-8issue
3eissn
0014-5793issn
1873-3468pii
0014-5793(94)00609-1journal_volume
348pub_type
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